Blistering skin disorders

Blistering Skin Disorders in the Neonate

Clinical Pediatrics ◽

10.1177/0009922811430347 ◽

2012 ◽

Vol 51 (7) ◽

pp. 685-688

Author(s):

Lauren Rimoin ◽

John M. Graham

Keyword(s):

Skin Disorders ◽

Blistering Skin Disorders

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Treatment of treatment-resistant autoimmune blistering skin disorders with rituximab

British Journal of Dermatology ◽

10.1111/j.1365-2133.2009.09132.x ◽

2009 ◽

Vol 160 (6) ◽

pp. 1359-1361 ◽

Cited By ~ 4

Author(s):

A.Ø. Jensen ◽

B.K. Møller ◽

A. Vangkilde ◽

B. Mark ◽

E.R. Obitz ◽

...

Keyword(s):

Skin Disorders ◽

Treatment Resistant ◽

Blistering Skin Disorders

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Evaluation of drug use heath related quality of life and pharmacoeconomics in autoimmune skin disorders: focus on blistering skin disorders-a prospective observational study

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20214506 ◽

2021 ◽

Vol 10 (12) ◽

pp. 1398

Author(s):

Deshna H. Lad ◽

Ashish Jagati ◽

Pooja Agarwal ◽

Supriya D. Malhotra

Keyword(s):

Quality Of Life ◽

Observational Study ◽

Prospective Observational Study ◽

Topical Steroid ◽

Systemic Steroid ◽

High Morbidity ◽

Skin Disorders ◽

Price Variation ◽

Blistering Skin Disorders

Background: Autoimmune skin disorders (ASDs) are complex diseases triggered by autoantibodies action against epidermal antigens or the dermo epidermal junction. Although rare, they present high morbidity, affecting the quality of life (QoL) of patients and financial status of patient.Methods: This prospective, observational study was carried out in department of dermatology for 2-3 months after ethical approval. Drug usage pattern, heath related QoL (HRQOL) by using DLQI (Dermatology life quality index) and cost were evaluated in patients with ASDs. Statistical analysis was done using Microsoft excel office 2019 and rechecked with SPSS (version 23.0). P<0.001 was considered as statistically significant.Results: Out of 73 patients enrolled, 32 were male and 41 were female with the mean age was 48.27±14.93 years; 55% patients had autoimmune blistering skin disorders (AIBDs) and 45% having other ASDs (OADs). Pemphigus vulgaris (PV) (35%) being the most common among all ASDs. Systemic steroid (60.27%), topical steroid (79.45%), levocetirizine (63%) were most commonly prescribed drugs. Mean DLQI score at baseline and after treatment was 11.64±2.49 and 6.8±2.75 respectively. It was highly significant statistically (p<0.0001). Total cost of illness per month was 813.64±481.21 INR. Maximum percentage variation in cost was seen with prednisolone (1706.28%).Conclusions: ASDs have a female bias and inflict severe impairment to the QoL of patients. Appropriate drug therapy with corticosteroids and other adjuvant drug lead to positive impact on QoL. There was very wide price variation of different brands of the same generic most commonly prednisolone and levocetirizine.

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