Trauma severity indices

2004 ◽  
pp. 70-80
Author(s):  
Julian Cooper
Keyword(s):  
Trauma Severity ◽  
Trauma Severity Indices

An Evaluation of Multiple Trauma Severity Indices Created by Different Index Development Strategies

Medical Care ◽  
1983 ◽  
Vol 21 (7) ◽  
pp. 674-691 ◽  
Author(s):  
David H. Gustafson ◽  
Dennis G. Fryback ◽  
Jerry H. Rose ◽  
Constance T. Prokop ◽  
Don E. Detmer ◽  
...  
Keyword(s):  
Multiple Trauma ◽  
Development Strategies ◽  
Trauma Severity ◽  
Trauma Severity Indices ◽  
Index Development

scholarly journals Expression of HO1 and PER2 can predict the incidence of delirium in trauma patients with concomitant brain injury

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Matti Steimer ◽  
Sandra Kaiser ◽  
Felix Ulbrich ◽  
Johannes Kalbhenn ◽  
Hartmut Bürkle ◽  
...  
Keyword(s):  
Brain Injury ◽  
Injury Severity ◽  
Kidney Injury ◽  
Diagnostic Tools ◽  
Heme Oxygenase 1 ◽  
Trauma Patients ◽  
Independent Manner ◽  
Equal Distribution ◽  
Expression Levels ◽  
Trauma Severity

AbstractIntensive care unit (ICU)-acquired delirium is associated with adverse outcome in trauma patients with concomitant traumatic brain injury (TBI), but diagnosis remains challenging. Quantifying circadian disruption by analyzing expression of the circadian gene period circadian regulator 2 (PER2) and heme oxygenase 1 (HO1), which determines heme turnover, may prove to be potential diagnostic tools. Expression of PER2 and HO1 was quantified using qPCR from blood samples 1 day and 7 days after trauma. Association analysis was performed comparing mRNA expression levels with parameters of trauma (ISS—injury severity score), delirium, acute kidney injury (AKI) and length of ICU stay. 48 polytraumatized patients were included (equal distribution of TBI versus non-TBI) corrected for ISS, age and gender using a matched pairs approach. Expression levels of PER2 and HO1 were independent of age (PER2: P = 0.935; HO1: P = 0.988), while expression levels were significantly correlated with trauma severity (PER2: P = 0.009; HO1: P < 0.001) and longer ICU length of stay (PER2: P = 0.018; HO1: P < 0.001). High expression levels increased the odds of delirium occurrence (PER2: OR = 4.32 [1.14–13.87]; HO1: OR = 4.50 [1.23–14.42]). Patients with TBI showed a trend towards elevated PER2 (OR = 3.00 [0.84–9.33], P = 0.125), but not towards delirium occurrence (P = 0.556). TBI patients were less likely to develop AKI compared to non-TBI (P = 0.022). Expression levels of PER2 and HO1 correlate with the incidence of delirium in an age-independent manner and may potentially improve diagnostic algorithms when used as delirium biomarkers.Trial registration: German Clinical Trials Register (Trial-ID DRKS00008981; Universal Trial Number U1111-1172-6077; Jan. 18, 2018).

Survivor Report of Trauma Severity Interview

2011 ◽  
Author(s):  
Natalya C. Maisel ◽  
Amy J. Rauer ◽  
Grant N. Marshall ◽  
Benjamin R. Karney
Keyword(s):  
Trauma Severity

Trauma-related mortality of patients with severe psychiatric disorders: population-based study from the French national hospital database

2019 ◽  
Vol 217 (4) ◽  
pp. 568-574
Author(s):  
Guillaume Fond ◽  
Vanessa Pauly ◽  
Thierry Bege ◽  
Veronica Orleans ◽  
David Braunstein ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Psychiatric Disorders ◽  
Psychiatric Diagnosis ◽  
Hospital Admissions ◽  
Social Deprivation ◽  
Sociodemographic Characteristics ◽  
Survival Prognosis ◽  
Trauma Severity ◽  
Increased Risk ◽  
Related Mortality

BackgroundMost research on mortality in people with severe psychiatric disorders has focused on natural causes of death. Little is known about trauma-related mortality, although bipolar disorder and schizophrenia have been associated with increased risk of self-administered injury and road accidents.AimsTo determine if 30-day in-patient mortality from traumatic injury was increased in people with bipolar disorder and schizophrenia compared with those without psychiatric disorders.MethodA French national 2016 database of 144 058 hospital admissions for trauma was explored. Patients with bipolar disorder and schizophrenia were selected and matched with mentally healthy controls in a 1:3 ratio according to age, gender, social deprivation and region of residence. We collected the following data: sociodemographic characteristics, comorbidities, trauma severity characteristics and trauma circumstances. Study outcome was 30-day in-patient mortality.ResultsThe study included 1059 people with bipolar disorder, 1575 people with schizophrenia and their respective controls (n = 3177 and n = 4725). The 30-day mortality was 5.7% in bipolar disorder, 5.1% in schizophrenia and 3.3 and 3.8% in the controls, respectively. Only bipolar disorder was associated with increased mortality in univariate analyses. This association remained significant after adjustment for sociodemographic characteristics and comorbidities but not after adjustment for trauma severity. Self-administered injuries were associated with increased mortality independent of the presence of a psychiatric diagnosis.ConclusionsPatients with bipolar disorder are at higher risk of 30-day mortality, probably through increased trauma severity. A self-administered injury is predictive of a poor survival prognosis regardless of psychiatric diagnosis.

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