Rectal Biopsies

2013 ◽  
pp. 564-568
Keyword(s):  
Rectal Biopsies

scholarly journals Multicenter Intestinal Current Measurements in Rectal Biopsies from CF and Non-CF Subjects to Monitor CFTR Function

PLoS ONE ◽  
2013 ◽  
Vol 8 (9) ◽  
pp. e73905 ◽  
Author(s):  
John P. Clancy ◽  
Rhonda D. Szczesniak ◽  
Melissa A. Ashlock ◽  
Sarah E. Ernst ◽  
Lijuan Fan ◽  
...  
Keyword(s):  
Rectal Biopsies

scholarly journals Impact of a decade of successful antiretroviral therapy initiated at HIV-1 seroconversion on blood and rectal reservoirs

eLife ◽  
2015 ◽  
Vol 4 ◽  
Author(s):  
Eva Malatinkova ◽  
Ward De Spiegelaere ◽  
Pawel Bonczkowski ◽  
Maja Kiselinova ◽  
Karen Vervisch ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Treatment Initiation ◽  
Cross Sectional Study ◽  
Functional Cure ◽  
Cross Sectional ◽  
Polymerase Chain ◽  
Low Levels ◽  
Rectal Biopsies ◽  
Hiv 1

Persistent reservoirs remain the major obstacles to achieve an HIV-1 cure. Prolonged early antiretroviral therapy (ART) may reduce the extent of reservoirs and allow for virological control after ART discontinuation. We compared HIV-1 reservoirs in a cross-sectional study using polymerase chain reaction-based techniques in blood and tissue of early-treated seroconverters, late-treated patients, ART-naïve seroconverters, and long-term non-progressors (LTNPs) who have spontaneous virological control without treatment. A decade of early ART reduced the total and integrated HIV-1 DNA levels compared with later treatment initiation, but not reaching the low levels found in LTNPs. Total HIV-1 DNA in rectal biopsies did not differ between cohorts. Importantly, lower viral transcription (HIV-1 unspliced RNA) and enhanced immune preservation (CD4/CD8), reminiscent of LTNPs, were found in early compared to late-treated patients. This suggests that early treatment is associated with some immunovirological features of LTNPs that may improve the outcome of future interventions aimed at a functional cure.

Immunohistochemical Detection of Amyloid AA in Formaline-Fixed Paraffine-Embedded Rectal Biopsies with the Monoclonal Anti-Human Saa Antibody Reu.86.2

1991 ◽  
pp. 809-812 ◽  
Author(s):  
Bouke P. C. Hazenberg ◽  
Joris Grond ◽  
Dicky Van Den Top ◽  
Johan Bijzet ◽  
Pieter C. Limburg ◽  
...  
Keyword(s):  
Immunohistochemical Detection ◽  
Rectal Biopsies

Dr. Orvar Swenson and the Pull-Through

2019 ◽  
Vol 85 (12) ◽  
pp. 1311-1313
Author(s):  
John J. Newland ◽  
Katerina Dukleska ◽  
Scott Cowan ◽  
Charles J. Yeo ◽  
Renee Tholey
Keyword(s):  
Pediatric Surgery ◽  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Toxic Megacolon ◽  
Bowel Function ◽  
Standard Textbook ◽  
Surgery Research ◽  
Peter Bent Brigham Hospital ◽  
Pull Through ◽  
Rectal Biopsies

Dr. Orvar Swenson is best remembered for developing the Swenson pull-through, a technique he developed to treat Hirschsprung's disease. After graduating from Harvard Medical School and beginning his residency at Peter Bent Brigham Hospital, Dr. Swenson observed that patients with Hirschsprung's disease and toxic megacolon resumed normal bowel function after placement of transverse colostomies. His observation led to studying the patency of his patients’ colons using barium enema contrast studies. At the collapsed portion of the colon, he performed rectal biopsies leading to the discovery that the cause of Hirschsprung's disease is that the collapsed portion of the colon lacks the Auerbach plexus. The Swenson pull-through removes this aganglionic portion of the colon and cures the patient. His career grew from there as he traveled to academic institutions teaching his technique. He is remembered fondly for his contributions to pediatric surgery through the restructuring of pediatric surgery departments, pediatric surgery research, and writing and editing multiple volumes of Pediatric Surgery, the standard textbook for pediatric surgeons. He died peacefully in 2012 at the age of 103 years.

Epithelial Cell Renewal in Cultured Rectal Biopsies in Ulcerative Colitis

1973 ◽  
Vol 64 (3) ◽  
pp. 383-390 ◽  
Author(s):  
Gregory L. Eastwood ◽  
Jerry S. Trier
Keyword(s):  
Ulcerative Colitis ◽  
Epithelial Cell ◽  
Cell Renewal ◽  
Rectal Biopsies
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