scholarly journals Estimating Incidence Trends in Regular Heroin Use in 26 Regions of Switzerland Using Methadone Treatment Data

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Marcelo Ribeiro ◽  
Rosana Frajzinger ◽  
Luciane Ogata Perrenoud ◽  
Benedikt Fischer

Purpose Brazil’s street-based drug use is mostly characterized by non-injection psychostimulant (e.g. crack-cocaine) drug use in Brazil, with limited interventions and service availability. Recently, an influx of multi-ethnic migrants within an urban drug scene in Sao Paulo was associated with heroin use, a drug normatively absent from Brazil. The purpose of this paper is to characterize and compare heroin use-related characteristics and outcomes for an attending sub-sample of clients from a large community-based treatment centre (“CRATOD”) serving Sao Paulo’s local urban drug scene. Design/methodology/approach All non-Brazilian patients (n = 109) receiving services at CRATOD for 2013–2016 were identified from patient files, divided into heroin users (n = 40) and non-heroin users (n = 69). Based on chart reviews, select socio-demographic, drug use and health status (including blood-borne-virus and other infections per rapid test methods) were examined and bi-variately compared. Multi-variate analyses examined factors independently associated with heroin use. Findings Most participants were male and middle-aged, poly-drug users and socio-economically marginalized. While heroin users primarily originated from Africa, they reported significantly more criminal histories, drug (e.g. injection) and sex-risk behaviors and elevated rates of BBV (e.g. Hepatitis C Virus and HIV). A minority of heroin users attending the clinic was provided methadone treatment, mostly for detoxification. Originality/value This study documented information on a distinct sample of mostly migration-based heroin users in Sao Paulo, Brazil. Based on the local experience, global migration dynamics can bring changes to established drug use cultures and services, including new challenges for drug use-related related behaviors and therapeutic interventions that require effective understanding and addressing.


2009 ◽  
Vol 28 (6) ◽  
pp. 608-615 ◽  
Author(s):  
RICHARD SENBANJO ◽  
KIM WOLFF ◽  
E. JANE MARSHALL ◽  
JOHN STRANG

Author(s):  
Bruce R. Lawford ◽  
Ross McD. Young ◽  
Ernest P. Noble ◽  
Joanne Sargent ◽  
John Rowell ◽  
...  

Medicina ◽  
2009 ◽  
Vol 45 (5) ◽  
pp. 419
Author(s):  
Dagmara Reingardienė ◽  
Liucija Jodžiūnienė ◽  
Robertas Lažauskas

Methadone is a long-acting synthetic opioid with high affinity for various opioid receptors, especially for μ-opioid receptors. Methadone has been used as a successful pharmacologic intervention for the treatment of heroin dependence and acute and chronic pain. This treatment is effective for opiate addiction, reducing morbidity and mortality associated with heroin use. However, overdosing with methadone has become a growing phenomenon because of the increased availability of this drug. Patients enrolled in a methadone maintenance treatment program may become physically dependent and may experience methadone withdrawal symptoms. In this review article, there are discussed about pharmacokinetic and pharmacodynamic properties of methadone, clinical symptoms of its overdose, dosage problems, detection of methadone in biological samples, treatment, and causes of methadone overdose-related deaths.


Addiction ◽  
2009 ◽  
Vol 104 (2) ◽  
pp. 248-255 ◽  
Author(s):  
Albert Sánchez-Niubò ◽  
Josep Fortiana ◽  
Gregorio Barrio ◽  
Josep Maria Suelves ◽  
Juan Francisco Correa ◽  
...  
Keyword(s):  

1984 ◽  
Vol 14 (4) ◽  
pp. 687-702 ◽  
Author(s):  
Dana E. Hunt ◽  
Douglas S. Lipton ◽  
Barry Spunt

Much prior research has looked at the changes in criminal activity of narcotics addicts when they enter methadone maintenance treatment programs. Because of the special nature of methadone, a drug which produces a cross-tolerance to other opiates in the user making continued heroin use difficult, the methadone treatment population has also been examined for answers to basic questions about the relationship between drug use and crime. This paper draws on interviews and ethnographic data collection with 368 methadone maintenance clients and 142 narcotics users not currently in treatment to explore the relationship between drug use and criminal activity. Results indicate that methadone clients are not only less involved in criminal activity than users not in treatment, but also among those clients who do continue criminal activity, there is less involvement in more serious crimes such as robbery, burglary, or dealing heroin and cocaine. The differences between those in treatment and those not in treatment are not a function of a lower level or criminal activity prior to treatment, but relate to being in treatment. Methadone clients who continue to commit crime are either clients continuing to use heroin and/or cocaine or clients for whom crime is an income or an income supplement.


2015 ◽  
Vol 21 (4) ◽  
pp. 179-187 ◽  
Author(s):  
Isabelle Demaret ◽  
Etienne Quertemont ◽  
Géraldine Litran ◽  
Cécile Magoga ◽  
Clémence Deblire ◽  
...  

Background/Aims: Heroin-assisted treatment (HAT) can improve the condition of heroin addicts still using street heroin after a methadone treatment. In Belgium, a new trial compared the efficacy of a HAT to existing methadone maintenance treatment. Methods: In this randomised controlled trial, HAT was limited to 12 months. Participants were assessed every 3 months. They were responders if they showed improvement on the level of street heroin use, health or criminal involvement. Results: 74 participants were randomised in the trial. The experimental group (n = 36) counted 30% of responders more than the control group (n = 38) at each assessment point (p < 0.05), except at 12 months where the difference (11%) was no longer significant (p = 0.35). Still, after 12 months, participants in the experimental group reported significantly greater improvements (p < 0.05) than the control group on the level of street heroin use and on the level of physical and mental health. Both groups reported significantly less criminal acts after 12 months (p < 0.001), but with no significant difference between the groups. Conclusions: This trial confirms the short-term efficacy of HAT for severe heroin addicts, who already failed methadone treatment.


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