Environmental Toxicology Monitoring with Polyazetidine- based Enzymatic Electrochemical Biosensors

2012 ◽  
pp. 165-185
Keyword(s):  
Environmental Toxicology ◽  
Electrochemical Biosensors

Letters. Environmental toxicology

1983 ◽  
Vol 17 (4) ◽  
pp. 160-160
Author(s):  
Jerry Hook
Keyword(s):  
Environmental Toxicology

THE ITALIAN TEACHING EXPERIENCE IN ENVIRONMENTAL TOXICOLOGY

2005 ◽  
Vol 4 (2) ◽  
pp. 189-194
Author(s):  
Patrizia Restani ◽  
Roberto Majocchi ◽  
Maria Pia Corsini ◽  
Corrado Lodovico Galli
Keyword(s):  
Teaching Experience ◽  
Environmental Toxicology

Electrochemical Biosensors as a Screening Tool of In Vitro DNA-Drug Interaction

2005 ◽  
Vol 1 (3) ◽  
pp. 217-224 ◽  
Author(s):  
Graziana Bagni ◽  
Mauro Ravera ◽  
Domenico Osella ◽  
Marco Mascini
Keyword(s):  
Drug Interaction ◽  
Screening Tool ◽  
Electrochemical Biosensors

scholarly journals The Role of Peptides in the Design of Electrochemical Biosensors for Clinical Diagnostics

Biosensors ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 246
Author(s):  
Patrick Severin Sfragano ◽  
Giulia Moro ◽  
Federico Polo ◽  
Ilaria Palchetti
Keyword(s):  
Functional Groups ◽  
Synthetic Peptides ◽  
Clinical Diagnostics ◽  
Electrochemical Biosensors ◽  
Practical Application ◽  
Design And Development ◽  
Electrode Surfaces ◽  
Electrochemical Transducers ◽  
Target Analyte

Peptides represent a promising class of biorecognition elements that can be coupled to electrochemical transducers. The benefits lie mainly in their stability and selectivity toward a target analyte. Furthermore, they can be synthesized rather easily and modified with specific functional groups, thus making them suitable for the development of novel architectures for biosensing platforms, as well as alternative labelling tools. Peptides have also been proposed as antibiofouling agents. Indeed, biofouling caused by the accumulation of biomolecules on electrode surfaces is one of the major issues and challenges to be addressed in the practical application of electrochemical biosensors. In this review, we summarise trends from the last three years in the design and development of electrochemical biosensors using synthetic peptides. The different roles of peptides in the design of electrochemical biosensors are described. The main procedures of selection and synthesis are discussed. Selected applications in clinical diagnostics are also described.

Trans-disciplinary diagnosis for an in-depth reform of regulatory expertise in the field of environmental toxicology and security

2021 ◽  
Author(s):  
Joël Spiroux de Vendômois ◽  
Jean-Paul Bourdineaud ◽  
Arnaud Apoteker ◽  
Nicolas Defarge ◽  
Emilie Gaillard ◽  
...  
Keyword(s):  
Environmental Toxicology

scholarly journals Electrochemical Biosensors for Cytokine Profiling: Recent Advancements and Possibilities in the Near Future

Biosensors ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 94
Author(s):  
Nirmita Dutta ◽  
Peter B. Lillehoj ◽  
Pedro Estrela ◽  
Gorachand Dutta
Keyword(s):  
Immune System ◽  
Cost Effective ◽  
Anomalous Behavior ◽  
Quantitative Detection ◽  
Electrochemical Biosensors ◽  
Aberrant Expression ◽  
Detection Techniques ◽  
Short Period ◽  
User Friendly ◽  
Cytokine Profiling

Cytokines are soluble proteins secreted by immune cells that act as molecular messengers relaying instructions and mediating various functions performed by the cellular counterparts of the immune system, by means of a synchronized cascade of signaling pathways. Aberrant expression of cytokines can be indicative of anomalous behavior of the immunoregulatory system, as seen in various illnesses and conditions, such as cancer, autoimmunity, neurodegeneration and other physiological disorders. Cancer and autoimmune diseases are particularly adept at developing mechanisms to escape and modulate the immune system checkpoints, reflected by an altered cytokine profile. Cytokine profiling can provide valuable information for diagnosing such diseases and monitoring their progression, as well as assessing the efficacy of immunotherapeutic regiments. Toward this goal, there has been immense interest in the development of ultrasensitive quantitative detection techniques for cytokines, which involves technologies from various scientific disciplines, such as immunology, electrochemistry, photometry, nanotechnology and electronics. This review focusses on one aspect of this collective effort: electrochemical biosensors. Among the various types of biosensors available, electrochemical biosensors are one of the most reliable, user-friendly, easy to manufacture, cost-effective and versatile technologies that can yield results within a short period of time, making it extremely promising for routine clinical testing.

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