When Clinical Best Practice Is Not Actual Practice

2012 ◽  
pp. 3-18
Keyword(s):  
Best Practice ◽  
Actual Practice ◽  
Clinical Best Practice

scholarly journals Clinical Best Practice Advice for Hepatology and Liver Transplant Providers During the COVID‐19 Pandemic: AASLD Expert Panel Consensus Statement

Hepatology ◽  
2020 ◽  
Vol 72 (1) ◽  
pp. 287-304 ◽  
Author(s):  
Oren K. Fix ◽  
Bilal Hameed ◽  
Robert J. Fontana ◽  
Ryan M. Kwok ◽  
Brendan M. McGuire ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Best Practice ◽  
Consensus Statement ◽  
Expert Panel ◽  
Clinical Best Practice

scholarly journals An Online Application for Retinoblastoma Surveillance

2020 ◽  
Vol 6 (5) ◽  
pp. 376-380
Author(s):  
Nakul Singh ◽  
Meghan J. DeBenedictis ◽  
Arun D. Singh
Keyword(s):  
Best Practice ◽  
Consensus Guidelines ◽  
Rb1 Gene ◽  
Online Application ◽  
Mutation Status ◽  
Clinical Scenarios ◽  
Specialized Care ◽  
Life Threatening ◽  
Tumor Phenotype ◽  
Clinical Best Practice

Background: Retinoblastoma (RB) is a potentially heritable childhood cancer that is vision- and life-threatening. Assessing the risk of inheriting RB is important for structuring ophthalmic and genetic screening of family members. Purpose: To create a free online application that integrates phenotypic, genetic, and familial relationships with clinical best practice surveillance guidelines for families with RB. Methods: The risk of germline RB1 gene mutation was assessed for first- and second-degree relatives of a proband under variable clinical scenarios, integrating age, phenotype, relationship data, and genotype (germline RB1 mutation status: detected, undetected, not tested). Based on the assessed risk of a germline RB1 mutation, recommendations regarding further genetic testing as well as ophthalmic surveillance were derived from consensus guidelines. Results: The recommendations depend on the RB1 germline mutation status (detected, undetected, not tested), which were further subcategorized by the results of tumor phenotype, relationship to proband, age of the relative, and family structure. The online application is available at https://nakul-singh.shinyapps.io/RB_Screening_rec/. Conclusions: The assessed risk of germline RB1 mutation determines ophthalmic surveillance recommendations. The tool may have most value in regions where access to specialized care is limited.

scholarly journals The Need for Education and Clinical Best Practice Guidelines in the Era of Direct-to-Consumer Genomic Testing

10.2196/21787 ◽  
2020 ◽  
Vol 6 (2) ◽  
pp. e21787
Author(s):  
Madeleine Myers ◽  
Cinnamon Bloss
Keyword(s):  
Primary Care ◽  
Primary Care Physicians ◽  
Best Practice ◽  
Care Setting ◽  
Genomic Testing ◽  
Personal Genomic ◽  
Direct To Consumer ◽  
Best Practice Guidelines ◽  
New Guidelines ◽  
Clinical Best Practice

Many people share the results of their direct-to-consumer personal genomic testing (DTC-PGT) within the primary care setting, seeking interpretation of and counsel about the results. However, most primary care physicians (PCPs) are not trained to interpret and communicate about DTC-PGT results. New guidelines must be developed to help PCPs maximize the potential of emerging DTC-PGT technologies.

Exercise prescription and tailored physical activity intervention in onco‐hematology inpatients, a personalized bedside approach to improve clinical best practice

2019 ◽  
Vol 37 (3) ◽  
pp. 277-284
Author(s):  
Federica Duregon ◽  
Stefano Gobbo ◽  
Valentina Bullo ◽  
Enrico Roma ◽  
Barbara Vendramin ◽  
...  
Keyword(s):  
Physical Activity ◽  
Best Practice ◽  
Physical Activity Intervention ◽  
Exercise Prescription ◽  
Clinical Best Practice
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