Cisplatin and Related Anticancer Drugs: Recent Advances and Insights

2004 ◽  
pp. 143-177 ◽  
Author(s):  
Katie R. Barnes ◽  
Stephen J. Lippard
Keyword(s):  
Anticancer Drugs ◽  
Recent Advances

Recent advances of nanotechnology for the delivery of anticancer drugs for breast cancer treatment

2019 ◽  
Vol 50 (3) ◽  
pp. 261-270 ◽  
Author(s):  
Phuong Tran ◽  
Sang-Eun Lee ◽  
Dong-Hyun Kim ◽  
Yong-Chul Pyo ◽  
Jeong-Sook Park
Keyword(s):  
Breast Cancer ◽  
Cancer Treatment ◽  
Anticancer Drugs ◽  
Breast Cancer Treatment ◽  
Recent Advances

Anthracyclines and ellipticines as DNA-damaging anticancer drugs: Recent advances

2012 ◽  
Vol 133 (1) ◽  
pp. 26-39 ◽  
Author(s):  
Rene Kizek ◽  
Vojtech Adam ◽  
Jan Hrabeta ◽  
Tomas Eckschlager ◽  
Svatopluk Smutny ◽  
...  
Keyword(s):  
Anticancer Drugs ◽  
Recent Advances

Cyclin dependent kinase (CDK) inhibitors as anticancer drugs: Recent advances (2015–2019)

2019 ◽  
Vol 29 (20) ◽  
pp. 126637 ◽  
Author(s):  
Concepción Sánchez-Martínez ◽  
María José Lallena ◽  
Sonia Gutiérrez Sanfeliciano ◽  
Alfonso de Dios
Keyword(s):  
Anticancer Drugs ◽  
Cdk Inhibitors ◽  
Cyclin Dependent Kinase ◽  
Recent Advances

Ruthenium(ii) complexes with dppz: from molecular photoswitch to biological applications

2016 ◽  
Vol 45 (34) ◽  
pp. 13261-13276 ◽  
Author(s):  
Guanying Li ◽  
Lingli Sun ◽  
Liangnian Ji ◽  
Hui Chao
Keyword(s):  
Dna Binding ◽  
Protein Aggregation ◽  
Present Article ◽  
Anticancer Drugs ◽  
Cellular Imaging ◽  
Biological Applications ◽  
Recent Advances

The present article describes the recent advances in biological applications of the Ru-dppz systems in DNA binding, cellular imaging, anticancer drugs, phototherapy, protein aggregation detecting and chemosensors.

Recent advances in galactose-engineered nanocarriers for the site-specific delivery of siRNA and anticancer drugs

2018 ◽  
Vol 23 (5) ◽  
pp. 960-973 ◽  
Author(s):  
Ashay Jain ◽  
Atul Jain ◽  
Prahlad Parajuli ◽  
Vijay Mishra ◽  
Gargi Ghoshal ◽  
...  
Keyword(s):  
Anticancer Drugs ◽  
Site Specific ◽  
Recent Advances

scholarly journals Pyrrole as an Important Scaffold of Anticancer Drugs: Recent Advances

2022 ◽  
Vol 25 ◽  
pp. 24-40
Author(s):  
Emilio Mateev ◽  
Maya Georgieva ◽  
Alexander Zlatkov
Keyword(s):  
Anticancer Drugs ◽  
Anticancer Agents ◽  
Tyrosine Kinases ◽  
Lipid Lowering ◽  
Pyrrole Derivatives ◽  
Design And Synthesis ◽  
Anticancer Properties ◽  
Highly Active ◽  
Recent Advances ◽  
Cytochrome P450 Family

With the significant increase of patients suffering from different types of cancer, it is evident that prompt measures in the development of novel and effective agents need to be taken. Pyrrole moiety has been found in various active compounds with anti-inflammatory, antiseptic, antibacterial, lipid-lowering and anticancer properties. Recent advances in the exploration of highly active and selective cytotoxic structures containing pyrrole motifs have shown promising data for future investigations. Accordingly, this review presents an overview of recent developments in the pyrrole derivatives as anticancer agents, with a main focus towards the key moieties required for the anti-tumor activities. Pyrrole molecules comprising prominent targeting capacities against microtubule polymerization, tyrosine kinases, cytochrome p450 family 1, histone deacetylase and bcl-2 proteins were reported. In addition, several mechanisms of action, such as apoptosis, cell cycle arrest, inhibiting kinases, angiogenesis, disruption of cell migration, modulation of nuclear receptor responsiveness and others were analyzed. Furthermore, in most of the discussed cases we provided synthesis schemes of the mentioned molecules. Overall, the utilization of pyrrole scaffold for the design and synthesis of novel anticancer drugs could be a promising approach for future investigations.  

Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs

2016 ◽  
Vol 108 ◽  
pp. 495-504 ◽  
Author(s):  
Jin Zhang ◽  
Xiangdong Jiang ◽  
Yingnan Jiang ◽  
Mingrui Guo ◽  
Shouyue Zhang ◽  
...  
Keyword(s):  
Anticancer Drugs ◽  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Recent Advances
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