Imported Case of Marburg Hemorrhagic Fever, in the Netherlands

2011 ◽  
pp. 213-218
2009 ◽  
Vol 15 (8) ◽  
pp. 1171-1175 ◽  
Author(s):  
Aura Timen ◽  
Marion P.G. Koopmans ◽  
Ann C.T.M. Vossen ◽  
Gerard J.J. van Doornum ◽  
Stephan Günther ◽  
...  

2021 ◽  
Author(s):  
Mathilde Uiterwijk ◽  
Adolfo Ibáñez-Justicia ◽  
Bart van de Vossenberg ◽  
Frans Jacobs ◽  
Paul Overgaauw ◽  
...  

Abstract Background: Ticks of the genus Hyalomma, which are vectors for several tick-borne diseases, are occasionally found in areas outside their endemic range including northern parts of Europe. The objective of this study was to analyse adult Hyalomma ticks that were recently found in The Netherlands. Methods: Hyalomma ticks were morphologically identified. Cluster analysis based upon sequence data (cox1 barcoding) for molecular identification and pathogen detection was performed. Additionally, a cross-sectional survey among horses was conducted to actively search for Hyalomma ticks in summer 2019. Analysis of temperature was done to assess the possibility of i) introduced engorged nymphs moulting to adults and ii) establishment of populations in The Netherlands. Results: Seventeen adult Hyalomma ticks (one in 2018, eleven in 2019, five in 2020) were found by citizens and reported. Fifteen ticks were detected on horses and two on humans. Twelve were identified as H. marginatum, one as H. rufipes and four, of which only photographic images were available, as Hyalomma sp. No Crimean-Congo Hemorrhagic Fever virus or Babesia/Theileria parasites were detected. One adult tick tested positive for Rickettsia aeschlimannii. In the cross-sectional horse survey, no Hyalomma ticks were found. Analysis of temperatures showed that engorged nymphs arriving on migratory birds in spring were able to moult to adults in 2019 and 2020, and that cumulative daily temperatures in The Netherlands were lower than in areas with established H. marginatum populations. Conclusions: Our results show that Hyalomma ticks are regularly introduced in The Netherlands as nymphs and these are able to develop to the adult stage under the Dutch weather conditions. Vigilant citizens can notify Hyalomma adult ticks, especially when attached to horses. Only one human pathogen, Rickettsia aeschlimannii, was found in one of the ticks. The risk of introduction of tick-borne diseases via Hyalomma ticks on migratory birds is considered to be low.


2009 ◽  
Vol 44 ◽  
pp. S27
Author(s):  
M.P.G. Koopmans ◽  
A.C.T.M. Vossen ◽  
S. Günther ◽  
J. van Dissel ◽  
K. Verduyn-Lunel ◽  
...  

2020 ◽  
Vol 7 (2) ◽  
Author(s):  
My V T Phan ◽  
Mariana Mendonca Melo ◽  
Els van Nood ◽  
Georgina Aron ◽  
Jolanda J C Kreeft-Voermans ◽  
...  

Abstract We report yellow fever infection in a Dutch traveler returning from Brazil. Yellow fever virus (YFV) was identified in serum and urine samples over a period of 1 month. Yellow fever virus genome sequences from the patient clustered with recent Brazilian YFV and showed with limited nucleotide changes during the resolving infection.


2017 ◽  
Vol 33 (S1) ◽  
pp. 68-69
Author(s):  
Anita Suijkerbuijk ◽  
Corien Swaan ◽  
Marie-Josee J. Mangen ◽  
Johan Polder ◽  
Aura Timen ◽  
...  

INTRODUCTION:Between December 2013 and April 2016, an unprecedented epidemic of Ebola Virus Disease (EVD) took place. This epidemic urged countries all over the world to be prepared for the possibility of having an EVD patient (1). Besides morbidity and mortality of the disease, containment efforts also have economic consequences for society. In this study, costs of preparedness for and response to EVD made by the Dutch health system were estimated.METHODS:We used an activity-based costing method in which cost of personnel time targeted at preparedness, and response activities was based on a time recording system and interviews with key professionals of the organizations involved. In addition, patient days of hospitalizations, laboratory tests, personal protective equipment (PPE), as well as costs for additional cleaning and disinfection were acquired via the organizations. All costs are expressed at the 2015-euro price level.RESULTS:The estimated total costs of EVD preparedness and response in the Netherlands were averaged at EUR14.1 million, ranging from EUR7.6 to EUR24.9 million. There were thirteen possible cases clinically evaluated and one confirmed case, admitted through an international evacuation request, corresponding to approximately EUR1 million per case (2). Preparedness activities of personnel, especially of all ambulance care services and hospitals that could possibly receive a case, and expenditures on PPE, were the main cost drivers.CONCLUSIONS:The estimated total cost of EVD preparedness and response in the Netherlands was substantial. Costs made by healthcare organizations were higher than among public health organizations (3). Designating one ambulance care service and fewer hospitals for the assessment of possible patients with viral hemorrhagic fever or other highly infectious disease of high consequence might improve efficiency and reduce future costs. The experiences and collaboration of healthcare organizations that managed patients with possible EVD can serve as a valuable resource for future outbreaks of other highly infectious diseases.


Viruses ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 443
Author(s):  
Tryntsje Cuperus ◽  
Ankje de Vries ◽  
Tabitha E. Hoornweg ◽  
Manoj Fonville ◽  
Ryanne I. Jaarsma ◽  
...  

Seoul virus (SEOV) is a zoonotic orthohantavirus carried by rats. In humans, SEOV can cause hemorrhagic fever with renal syndrome. Recent human SEOV cases described in the USA, United Kingdom, France and the Netherlands were associated with contact with pet or feeder rats. The prevalence of SEOV in these types of rats is unknown. We collected 175 pet and feeder rats (Rattus norvegicus) from private owners, ratteries and commercial breeders/traders in the Netherlands. Lung tissue of the rats was tested using a SEOV real-time RT-qPCR and heart fluid was tested for the presence of antibodies against SEOV. In all three investigated groups, RT-qPCR-positive rats were found: in 1/29 rats from private owners (3.6%), 2/56 rats from ratteries (3.4%) and 11/90 rats from commercial breeders (12.2%). The seroprevalence was largely similar to the prevalence calculated from RT-qPCR-positive rats. The SEOV sequences found were highly similar to sequences previously found in domesticated rats in Europe. In conclusion, SEOV is spread throughout different populations of domesticated rats.


2015 ◽  
Vol 2 (2) ◽  
pp. 11
Author(s):  
Darija Knežević ◽  
Duška Jović

Ebola, previously known as Ebola hemorrhagic fever, is a rare and deadly disease caused by infection with one of the Ebola virus strains. Starting from February 2014, the Ebola virus outbreak had spread across West African countries within a few months and caused great concerns of the World Health Organization. Currently there are no effective vaccines and drugs that are available for the prevention and treatment of infection with Ebola virus. Medical personnel caring for patients with suspect or confirmed Ebola viral disease is particularly exposed to the risk of suffering from this dangerous disease. It is important for frontline medical providers to understand key aspects of Ebola virus disease to quickly recognize an imported case, provide appropriate medical care, and prevent transmission. This paper gives a brief overview of the epidemics and pandemics, the biological characteristics of Ebola virus, the potential antiviral drugs and vaccines, as well as preventive measures.* 31 . July 2015, is said to have discovered an effective vaccine against Ebola virus http://www.thelancet.com/pb/assets/raw/Lancet/pdfs/S0140673615611175.pdf (note editor).


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