Risk Areas for Cryptococcus gattii, Vancouver Island, Canada

2011 ◽  
pp. 179-183
Keyword(s):  
Vancouver Island ◽  
Cryptococcus Gattii ◽  
Risk Areas

scholarly journals A rare genotype of Cryptococcus gattii caused the cryptococcosis outbreak on Vancouver Island (British Columbia, Canada)

2004 ◽  
Vol 101 (49) ◽  
pp. 17258-17263 ◽  
Author(s):  
S. E. Kidd ◽  
F. Hagen ◽  
R. L. Tscharke ◽  
M. Huynh ◽  
K. H. Bartlett ◽  
...  
Keyword(s):  
British Columbia ◽  
Vancouver Island ◽  
Cryptococcus Gattii

scholarly journals Tourism and Specific Risk Areas forCryptococcus gattii, Vancouver Island, Canada

2008 ◽  
Vol 14 (11) ◽  
pp. 1781-1783 ◽  
Author(s):  
Catharine Chambers ◽  
Laura MacDougall ◽  
Min Li ◽  
Eleni Galanis
Keyword(s):  
Vancouver Island ◽  
Specific Risk ◽  
Risk Areas

scholarly journals Surveillance for Cryptococcus gattii in horses of Vancouver Island, British Columbia, Canada

2011 ◽  
Vol 49 (7) ◽  
pp. 734-738 ◽  
Author(s):  
C. Duncan ◽  
K. H. Bartlett ◽  
S. Lester ◽  
B. Bobsien ◽  
J. Campbell ◽  
...  
Keyword(s):  
British Columbia ◽  
Vancouver Island ◽  
Cryptococcus Gattii

scholarly journals Cryptococcus gattii: An Emerging Cause of Pulmonary Nodules

2008 ◽  
Vol 15 (3) ◽  
pp. 153-157 ◽  
Author(s):  
Gary J Dewar ◽  
James K Kelly
Keyword(s):  
Central Nervous System ◽  
Health Care Professionals ◽  
Clinical Course ◽  
Pulmonary Nodules ◽  
Vancouver Island ◽  
Cryptococcus Gattii ◽  
Review Of The Literature ◽  
Endemic Focus ◽  
Serotype B

BACKGROUND: Since the fall of 1999, a new endemic focus ofCryptococcus gattiiserotype B infection has emerged on Vancouver Island (Victoria, British Columbia), with infections occurring in both animals and humans. In the human cases, symptoms have manifested as pulmonary nodules, meningitis or both. This organism has added a new nonmalignant cause of pulmonary nodules to the literature, resulting in a change in the management of these nodules by health care professionals.METHODS: A search of the number of cases recorded and treated in hospitals of the Vancouver Island Health Authority, along with a review of the literature regarding this emerging organism, was undertaken. The pathology, epidemiology and clinical course of this previously uncommon fungus was determined, and representative cases were chosen for illustration.RESULTS: More than 130 cases were recorded in the six-year period from late 1999 to mid-July 2006. The number of cases increased steadily over this period, but appears to be levelling off. Representative cases with medical imaging, along with photos of the pathology, are included. Recommendations for diagnosis, treatment and follow-up are outlined.CONCLUSIONS: The emergence of cryptococcal lung and central nervous system lesions on Vancouver Island have made it important to include travel to or residence of the island as part of the history in patients with pulmonary nodules. A registry of patients from Vancouver Island has been established, and it may be of value to include nonisland patients who are found to be infected with this organism.

scholarly journals Cryptococcus gattii in the Age of Whole-Genome Sequencing

mBio ◽  
2015 ◽  
Vol 6 (6) ◽  
Author(s):  
Wieland Meyer
Keyword(s):  
Whole Genome Sequencing ◽  
Pacific Northwest ◽  
Genome Sequencing ◽  
Chromosomal Rearrangements ◽  
The United States ◽  
Vancouver Island ◽  
Cryptococcus Gattii ◽  
Ancestral Population ◽  
Whole Genome ◽  
Content Type

ABSTRACT Cryptococcus gattii, the sister species of Cryptococcus neoformans, is an emerging pathogen which gained importance in connection with the ongoing cryptococcosis outbreak on Vancouver Island. Many molecular studies have divided this species into for major lineages: VGI, VGII, VGIII, and VGIV. This commentary summarizes the whole-genome sequencing (WGS) studies that have been carried out with this species, re-emphasizing the phylogenetic relationships, showing chromosomal rearrangements between those four groups, and identifying VGII as ancestral population within C. gattii. In addition, WGS specific to VGII, containing the Vancouver Island outbreak genotypes and those from the Pacific Northwest region of the United States, has placed the origin of this lineage within South America and identified specific genes responsible for either brain or lung infection. It also showed, that many genotypes are spread across a number of different continents, as has been previously shown by multilocus sequence typing (MLST). In addition, it showed that recombination occurs more frequently between mitochondrial than nuclear genomes.

scholarly journals Global VGIIa isolates are of comparable virulence to the major fatal Cryptococcus gattii Vancouver Island outbreak genotype

2011 ◽  
Vol 17 (2) ◽  
pp. 251-258 ◽  
Author(s):  
P. Ngamskulrungroj ◽  
C. Serena ◽  
F. Gilgado ◽  
R. Malik ◽  
W. Meyer
Keyword(s):  
Vancouver Island ◽  
Cryptococcus Gattii

scholarly journals Searching for clues for eighteen years: Deciphering the ecological determinants of Cryptococcus gattii on Vancouver Island, British Columbia

2017 ◽  
Vol 56 (2) ◽  
pp. 129-144 ◽  
Author(s):  
Emily Sohanna Acheson ◽  
Eleni Galanis ◽  
Karen Bartlett ◽  
Sunny Mak ◽  
Brian Klinkenberg
Keyword(s):  
British Columbia ◽  
Vancouver Island ◽  
Cryptococcus Gattii

scholarly journals Cryptococcus gattii Virulence Composite: Candidate Genes Revealed by Microarray Analysis of High and Less Virulent Vancouver Island Outbreak Strains

PLoS ONE ◽  
2011 ◽  
Vol 6 (1) ◽  
pp. e16076 ◽  
Author(s):  
Popchai Ngamskulrungroj ◽  
Jennifer Price ◽  
Tania Sorrell ◽  
John R. Perfect ◽  
Wieland Meyer
Keyword(s):  
Candidate Genes ◽  
Microarray Analysis ◽  
Vancouver Island ◽  
Cryptococcus Gattii

The Emergence of Cryptococcus gattii Infections on Vancouver Island and Expansion in the Pacific Northwest

Cryptococcus ◽  
2014 ◽  
pp. 313-325 ◽  
Author(s):  
Karen Bartlett ◽  
Edmond Byrnes ◽  
Colleen Duncan ◽  
Murray Fyfe ◽  
Eleni Galanis ◽  
...  
Keyword(s):  
Pacific Northwest ◽  
Vancouver Island ◽  
Cryptococcus Gattii ◽  
The Pacific
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