Unipolar Motor Circuits and Programs

2017 ◽  
pp. 403-466
Author(s):  
Julio Sanchez ◽  
Maria P. Canton
Keyword(s):  
Motor Circuits

scholarly journals A neuronal ensemble encoding adaptive choice during sensory conflict in Drosophila

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Preeti F. Sareen ◽  
Li Yan McCurdy ◽  
Michael N. Nitabach
Keyword(s):  
Food Choice ◽  
Internal State ◽  
Relevant Information ◽  
Food Choices ◽  
Small Population ◽  
Sensory Conflict ◽  
Shaped Body ◽  
Motor Circuits ◽  
Specific Subset ◽  
Adaptive Choice

AbstractFeeding decisions are fundamental to survival, and decision making is often disrupted in disease. Here, we show that neural activity in a small population of neurons projecting to the fan-shaped body higher-order central brain region of Drosophila represents food choice during sensory conflict. We found that food deprived flies made tradeoffs between appetitive and aversive values of food. We identified an upstream neuropeptidergic and dopaminergic network that relays internal state and other decision-relevant information to a specific subset of fan-shaped body neurons. These neurons were strongly inhibited by the taste of the rejected food choice, suggesting that they encode behavioral food choice. Our findings reveal that fan-shaped body taste responses to food choices are determined not only by taste quality, but also by previous experience (including choice outcome) and hunger state, which are integrated in the fan-shaped body to encode the decision before relay to downstream motor circuits for behavioral implementation.

Formation and plasticity of motor circuits in Drosophila

2009 ◽  
Vol 65 ◽  
pp. S7
Author(s):  
Akinao Nose ◽  
Hiroshi Kohsaka ◽  
Yukari Tachi ◽  
Satoko Okusawa
Keyword(s):  
Motor Circuits

A critical period that shapes neuronal motor circuits

Nature ◽  
2021 ◽  
Vol 592 (7854) ◽  
pp. 360-361
Author(s):  
Laura Sancho ◽  
Nicola J. Allen
Keyword(s):  
Critical Period ◽  
Motor Circuits

Hemispheric Coordination Is Necessary for Song Production in Adult Birds: Implications for a Dual Role for Forebrain Nuclei in Vocal Motor Control

2008 ◽  
Vol 99 (1) ◽  
pp. 373-385 ◽  
Author(s):  
Robin C. Ashmore ◽  
Mark Bourjaily ◽  
Marc F. Schmidt
Keyword(s):  
Anterior Commissure ◽  
Temporal Structure ◽  
Dual Role ◽  
Critical Feature ◽  
Motor Circuits ◽  
Output Structure ◽  
Complex Motor ◽  
Song Production ◽  
Song Control ◽  
Avian Song

Precise coordination across hemispheres is a critical feature of many complex motor circuits. In the avian song system the robust nucleus of the arcopallium (RA) plays a key role in such coordination. It is simultaneously the major output structure for the descending vocal motor pathway, and it also sends inputs to structures in the brain stem and thalamus that project bilaterally back to the forebrain. Because all birds lack a corpus callosum and the anterior commissure does not interconnect any of the song control nuclei directly, these bottom-up connections form the only pathway that can coordinate activity across hemispheres. In this study, we show that unilateral lesions of RA in adult male zebra finches ( Taeniopigia guttata) completely and permanently disrupt the bird's stereotyped song. In contrast, lesions of RA in juvenile birds do not prevent the acquisition of normal song as adults. These results highlight the importance of hemispheric interdependence once the circuit is established but show that one hemisphere is sufficient for complex vocal behavior if this interdependence is prevented during a critical period of development. The ability of birds to sing with a single RA provides the opportunity to test the effect of targeted microlesions in RA without confound of functional compensation from the contralateral RA. We show that microlesions cause significant changes in song temporal structure and implicate RA as playing a major part in the generation of song temporal patterns. These findings implicate a dual role for RA, first as part of the program generator for song and second as part of the circuit that mediates interhemispheric coordination.

scholarly journals Distinct roles for motor cortical and thalamic inputs to striatum during motor learning and execution

2019 ◽  
Author(s):  
Steffen B. E. Wolff ◽  
Raymond Ko ◽  
Bence P. Ölveczky
Keyword(s):  
Motor Cortex ◽  
Motor Learning ◽  
Learning Process ◽  
Brain Areas ◽  
Thalamic Neurons ◽  
Cortical Input ◽  
Motor Circuits ◽  
Motor Network ◽  
Motor Cortical ◽  
Cortical Inputs

AbstractThe acquisition and execution of learned motor sequences are mediated by a distributed motor network, spanning cortical and subcortical brain areas. The sensorimotor striatum is an important cog in this network, yet how its two main inputs, from motor cortex and thalamus respectively, contribute to its role in motor learning and execution remains largely unknown. To address this, we trained rats in a task that produces highly stereotyped and idiosyncratic motor sequences. We found that motor cortical input to the sensorimotor striatum is critical for the learning process, but after the behaviors were consolidated, this corticostriatal pathway became dispensable. Functional silencing of striatal-projecting thalamic neurons, however, disrupted the execution of the learned motor sequences, causing rats to revert to behaviors produced early in learning and preventing them from re-learning the task. These results show that the sensorimotor striatum is a conduit through which motor cortical inputs can drive experience-dependent changes in subcortical motor circuits, likely at thalamostriatal synapses.

scholarly journals Primate homologs of mouse cortico-striatal circuits

eLife ◽  
2020 ◽  
Vol 9 ◽  
Author(s):  
Joshua Henk Balsters ◽  
Valerio Zerbi ◽  
Jerome Sallet ◽  
Nicole Wenderoth ◽  
Rogier B Mars
Keyword(s):  
Prefrontal Cortex ◽  
Resting State ◽  
Resting State Fmri ◽  
Fmri Data ◽  
Fingerprint Matching ◽  
Motor Circuits ◽  
Connectivity Patterns ◽  
Species Comparisons ◽  
Similarities And Differences ◽  
Anterior Prefrontal Cortex

With the increasing necessity of animal models in biomedical research, there is a vital need to harmonise findings across species by establishing similarities and differences in rodent and primate neuroanatomy. Using connectivity fingerprint matching, we compared cortico-striatal circuits across humans, non-human primates, and mice using resting-state fMRI data in all species. Our results suggest that the connectivity patterns for the nucleus accumbens and cortico-striatal motor circuits (posterior/lateral putamen) were conserved across species, making them reliable targets for cross-species comparisons. However, a large number of human and macaque striatal voxels were not matched to any mouse cortico-striatal circuit (mouse->human: 85% unassigned; mouse->macaque 69% unassigned; macaque->human; 31% unassigned). These unassigned voxels were localised to the caudate nucleus and anterior putamen, overlapping with executive function and social/language regions of the striatum and connected to prefrontal-projecting cerebellar lobules and anterior prefrontal cortex, forming circuits that seem to be unique for non-human primates and humans.

Actions, Words, and Numbers

2008 ◽  
Vol 17 (5) ◽  
pp. 313-317 ◽  
Author(s):  
Michael Andres ◽  
Etienne Olivier ◽  
Arnaud Badets
Keyword(s):  
Motor System ◽  
Semantic Knowledge ◽  
Functional Brain Imaging ◽  
Adult Brain ◽  
Future Research ◽  
Number Representation ◽  
Motor Circuits ◽  
Magnitude Processing ◽  
Finger Counting ◽  
Report Data

Recent findings in neuroscience challenge the view that the motor system is exclusively dedicated to the control of actions, and it has been suggested that it may contribute critically to conceptual processes such as those involved in language and number representation. The aim of this review is to address this issue by illustrating some interactions between the motor system and the processing of words and numbers. First, we detail functional brain imaging studies suggesting that motor circuits may be recruited to represent the meaning of action-related words. Second, we summarize a series of experiments demonstrating some interference between the size of grip used to grasp objects and the magnitude processing of words or numbers. Third, we report data suggestive of a common representation of numbers and finger movements in the adult brain, a possible trace of the finger-counting strategies used in childhood. Altogether, these studies indicate that the motor system interacts with several aspects of word and number representations. Future research should determine whether these findings reflect a causal role of the motor system in the organization of semantic knowledge.

Sign in / Sign up

Export Citation Format

Share Document