Modern Pharmacological Classiˆcation of Ayurvedic Herbs

2012 ◽  
pp. 316-327 ◽  
Keyword(s):  
2004 ◽  
Vol 24 (5) ◽  
pp. 355-361 ◽  
Author(s):  
Ljiljana Mojovic ◽  
Karen P. Dierksen ◽  
Rosalyn H. Upson ◽  
Bruce A. Caldwell ◽  
Jeannine R. Lawrence ◽  
...  
Keyword(s):  

2021 ◽  
pp. 144-149
Author(s):  
K. Indumathi ◽  
E. Theranirajan ◽  
G. Bhavani

BACKGROUND: This is a retrospective study of 60 cases, to detect the expression of ER, PR, HER2neu, CK5/6 and Ki67 proliferation index in breast carcinomas by immunohistochemical method and to determine the newer molecular classication. Few patients have recurrence inspite of being diagnosed under the category of low risk and few do well in the high risk group which can be attributed to the molecular level differentiation. AIM: The aim of this study is to categorize the patients under molecular classication, and to compare the clinicopathological parameters with it and to denote the signicance of targeted therapy. MATERIALS AND METHODS: A retrospective study of detecting the expression of the above said markers in modied radical mastectomy specimens received at a tertiary care centre during the period from January 2015 to June 2018. A total of 60 cases which included 30 of IDC NST and 30 cases of special variants were selected for immunohistochemical analysis. RESULTS: Out of the 60 cases studied, the most common was found to be the luminal A type comprising 37% and the least common was the luminal B and hybrid types each comprising 8%. The most common grade for HER2 was Grade III (50%). The association of histological grade with the molecular classication was statistically signicant with the p value of 0.01. Basal type (56%) had the highest incidence of N3 stage. ER, PR, HER2 neu, CK5/6 expression and proliferation index with Ki67 had a statistically signicant association with the molecular classication. High proliferation index (>14%) with Ki67 was noted in Luminal B, Basal and Hybrid types. 78% of the total 60 cases were alive and healthy. One death was reported in HER2, Hybrid and Basal types. The negative kappa value obtained while studying the agreement between the histopathological and molecular classication, indicates that the agreement is worse than chance and hence the importance of molecular classication is substantiated for the targeted therapy.


2021 ◽  
pp. 31-32
Author(s):  
Sheeba Rana ◽  
Vicky Bakshi ◽  
Yavini Rawat ◽  
Zaid Bin Afroz

INTRODUCTION: Various chest X-ray scoring systems have been discovered and are employed to correlate with clinical severity, outcome and progression of diseases. With, the coronavirus outbreak, few chest radiograph classication were formulated, like the BSTI classication and the Brixia chest X-ray score. Brixia CXR scoring is used for assessing the clinical severity and outcome of COVID-19. This study aims to compare the Brixia CXR score with clinical severity of COVID-19 patients. MATERIAL& METHODS:This was a retrospective study in which medical records of patients aged 18 years or above, who tested for RTPCR or st st Rapid Antigen Test (RAT) for COVID positive from 1 February 2021 to 31 July 2021 (6 months) were taken. These subjects were stratied into mild, moderate and severe patients according to the ICMR guidelines. Chest X Rays were obtained and lesions were classied according to Brixia scoring system. RESULTS: Out of these 375 patients, 123 (32.8%) were female and 252 (67.2%) were male subjects. The average brixia score was 11.12. Average Brixia CXR score for mild, moderate and severe diseased subjects were 5.23, 11.20, and 14.43 respectively. DISCUSSION:The extent of chest x-ray involvement is proportional to the clinical severity of the patient. Although, a perplexing nding was that the average Brixia score of the female subjects were slightly higher than their male counterparts in the same clinical groups. CONCLUSION: Brixia CXR score correlates well with the clinical severity of the COVID-19.


2016 ◽  
Vol 6 (12) ◽  
pp. 998-1000
Author(s):  
SM Jha ◽  
AKS Dangol ◽  
S Shakya ◽  
B Jha

Background: Leprosy has a broad spectrum of clinical manifestations. Clinical information along with Bacterial evidence is necessary to achieve accurate diagnosis. The present study was carried out to nd out clinical and bacterial correlation in various presentations according to Ridley Jopling classi cation of Hansen’s Disease. Materials and Methods: It was a hospital based cross-sectional comparative study of 72 leprosy patients over a period of 1 year and it’s clinico-Bacterial correlation was done with the help of Slit Skin Smear and clinical classi cation. Results: This study included 72 leprosy patients at various stages according to Ridley Jopling classi cation. Maximum cases belonged to Borderline Tuberculoid leprosy 28(38.88%) followed by Tuberculoid leprosy 15(20.83%). Slit Skin Smear showed 12(42.85%) of Borderline Tuberculoid and 3(20%) of Tuberculoid cases had disparity and didn’t match corresponding clinical subtype. Conclusion: Clinical features along with Bacterial index is useful in making accurate diagnosis so that appropriate treatment could be started and hence deformity and disability could be prevented. 


Aksara ◽  
2021 ◽  
Vol 32 (2) ◽  
pp. 223-234
Author(s):  
Ni Nyoman Tanjung Turaeni ◽  
Puji Retno Hardiningtyas

Abstrak Kritik sosial sebagai sebuah ide atau berbagai bentuk gagasan yang bertolak belakang dengan kenyataan yang tidak sesuai dengan tujuan dan harapan dari tatanan dalam masyarakat. Penelitian ini bertujuan membahas aspek sosial yang meliputi struktur cerita, masalah sosial dan kritik sosial bermuatan lokal Bali yang tercermin dalam kumpulan cerita pendek berbahasa Bali Nguntul Tanah Nulengék Langit karya I Made Suarsa. Metode analisis yang digunakan dalam penelitian ini adalah deskriptif kualitatif dan teknik interpretatif. Dalam pengolahan data dilakukan tahapan klasifikasi, pendeskripsian, penerjemahan, dan penganalisisan data. Untuk mengetahui masalah sosial dan kritik sosial dalam cerpen tersebut, digunakan teori sosiologi sastra dan teori struktural untuk mengetahui struktur formal yang membangun cerita tersebut. Hasil dan pembahasan penelitian ini menunjukkan bahwa kritik sosial yang dapat terhimpun dalam cerita tersebut adalah kritik sosial terhadap kemiskinan, kritik sosial disorganisasi keluarga dan kritik terhadap adat dan tradisi serta serta kehidupan sosial masyarakat Bali. Dengan demikian, lahirnya cerpen karya I Made Suarsa ini memperlihatkan kemegahan pariwisata, masih terdapat ketimpangan sosial dalam masyarakat Bali. Kata kunci: cerpen, kritik sosial, masalah sosial, muatan lokal Bali Abstract Social criticism as an idea or various forms of ideas that are contrary to reality is not in accordance with the goals and expectations of the order in society. This study aims to discuss the social aspects which include story structure, social issues and social criticism with local Balinese content as re ected in a collection of short stories in Balinese language “Nguntul Tanah Nulengék Langit” by I Made Suarsa. The method used in this research is descriptive qualitative and note taking techniques. In data processing, the stages of classi cation, description, translation and data analysis are carried out. To nd out the social problems and social criticism in the short story, the sociology approach of Sapardi Djoko Damono’s view is used and is assisted by a structural approach to determine the formal structure that builds the story. The results of the study show that the social criticisms that can be collected in the story are social criticism of poverty, social criticism of family disorganization and criticism of customs and traditions as well as the social life of Balinese people who seem famous by tourism, but in fact there are still social inequalities in Balinese society. Keywords: social problems, social criticism, short stories 


2021 ◽  
pp. 8-10
Author(s):  
Vipul K. Srivastava ◽  
Rahul Khanna ◽  
Ramniwas Meena ◽  
Siddharth Khanna ◽  
Chandradeep Singh ◽  
...  

Introduction: Acute Pancreatitis (AP) is a potentially life threatening disease with varying severity of presentation from mild pain to persistent organ failure. D-dimer is an indirect measure of brin degradation products. It is a stable molecule with half-life of 4-8 hours. Material &Method: This is a prospective study done on 60 patients of acute pancreatitis treated at Department of General Surgery, Sir Sunderlal Hospital IMS BHU Varanasi, UPfrom the period of 2016 to 2018. Patients with diagnosis of APas per revised Atlanta classication were taken and D-dimer level was assessed at the time of presentation and patients were followed to assess the severity of disease and outcome. The D-dimer values were correlated with the Glasgow-Imrie score as well as the CTseverity index (CTSI) Result: Median value of D-dimer was found to be 3.68 mg/IFEU among the cases and 0.3 mg/IFEU among healthy volunteers. D-dimer levels increased as per CTSI severity score ranging from 2.97 to >5.70 mg/IFEU along with increased mortality in patients whom D-dimer levels were found to be high. D-dimer also showed positive correlation with Glasgow–Imrie score. Conclusion: Determining the serum concentration of D-dimer on day of admission is helpful in earlier prediction and assessment of severity of AP.


2021 ◽  
pp. 53-56
Author(s):  
G. Thenmozhi ◽  
Shobana Priya K

This study aimed to determine whether maternal age, maternal education , socio-economic status are factors for still births and identify the high risk age group which are likely to get affected , determine the signicant maternal medical conditions which are attributed to stillbirths and signicant obstetrics causes which are attributed to stillbirths. A cross-sectional hospital based study in government medical college hospital, chengalpattu was conducted. Data relating to socio- demographic information , passed obstetric history, associated medical conditions, index pregnancy characteristics where collected . economic classication was based on B.G.prasad's recommendation. medical and obstetric causes classied based on ReCoDe classication. Out of 11023 births from june 2016- may 2017 121 still births incidents were recorded at chengalpattu amounting to 11\1000 still birth incidents. The study showed mothers age between 19 and 21 is high risk group, literacy level has a positive impact in preventing stillbirths, economic status is a inuencing factor for stillbirth and placenta related complications remains a major causative factor of still birth followed by clinical conditions of the mother. The study could not establish any cross dependency on the variables and most of the factors have an independent inuence on the outcome.It is recommended that importance of antenatal care need to be communicated to the society especially to young mothers and practiced efciently


2021 ◽  
pp. 11-13
Author(s):  
C.Bhanu Sree ◽  
P. Annapurna ◽  
M. Rajani

Background: Meningiomas are neoplasms arising from the arachnoidal cap cells in the meningeal coverings of the spinal cord and brain. These are the most common benign intracranial tumours and account for about 13-26% of all primary brain neoplasms. These are generally benign neoplasms of adults most often seen in middle age, but about 10% are atypical or malignant. These neoplasms are graded by WHO as Grade I , II and III . Benign meningiomas can be cured by surgical resection where as higher grade meningiomas require radiotherapy after surgical resection as these higher grade meningiomas have greater recurrence and aggressive behavior. Aims and Objectives: To study the variants and histopathological spectrum of meningioma and prognosis of variants. Material & Methods: The present study is a prospective study conducted in the department of Pathology, Siddhartha medical college from June 2019-May 2020. During this study, 16 cases of meningiomas were diagnosed and reviewed. Result:In our study of 16 cases females were 62.5%. The most common age group is 41-60 yrs (68.75%). Most common variant was noted to be transitional meningioma followed by meningothelial meningioma. Out of the 16 cases, grade I were 81.25%. Conclusion: Meningiomas account for 28-30% of primary central nervous system tumors and unveil a heterogeneous histopathology. The histological appearance of meningioma determines the grading for the management of the various subtypes and also associated with patient's prognosis. Hence a continuous revision of histopathological classication systems is required to improve the diagnostic accuracy. Benign meningiomas are the most common type. From our study, we conclude that transitional meningioma is the most common benign variant.


Sign in / Sign up

Export Citation Format

Share Document