Iron and Ethylcellulose Nanoplatforms for Cancer Targeting

2011 ◽  
pp. 131-149
Keyword(s):  
Cancer Targeting

HER2 overexpression and cancer targeting

2001 ◽  
Vol 28 (5N) ◽  
pp. 115-124 ◽  
Author(s):  
Shao-Chun Wang ◽  
Mien-Chie Hung
Keyword(s):  
Cancer Targeting ◽  
Her2 Overexpression

scholarly journals Recent Advances of Nanotechnology-Facilitated Bacteria-Based Drug and Gene Delivery Systems for Cancer Treatment

Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 940
Author(s):  
Chaojie Zhu ◽  
Zhiheng Ji ◽  
Junkai Ma ◽  
Zhijie Ding ◽  
Jie Shen ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Cancer Treatment ◽  
Delivery Systems ◽  
Cancer Targeting ◽  
Cancer Treatments ◽  
Recent Advances ◽  
Therapeutic Mechanisms ◽  
Bacterial Therapy ◽  
Targeting Ability ◽  
Drug And Gene Delivery

Cancer is one of the most devastating and ubiquitous human diseases. Conventional therapies like chemotherapy and radiotherapy are the most widely used cancer treatments. Despite the notable therapeutic improvements that these measures achieve, disappointing therapeutic outcome and cancer reoccurrence commonly following these therapies demonstrate the need for better alternatives. Among them, bacterial therapy has proven to be effective in its intrinsic cancer targeting ability and various therapeutic mechanisms that can be further bolstered by nanotechnology. In this review, we will discuss recent advances of nanotechnology-facilitated bacteria-based drug and gene delivery systems in cancer treatment. Therapeutic mechanisms of these hybrid nanoformulations are highlighted to provide an up-to-date understanding of this emerging field.

Evaluation of 99mTc-labeled glutathione as a colon cancer targeting probe

2021 ◽  
Vol 327 (2) ◽  
pp. 673-689
Author(s):  
Sumeera Sidiq ◽  
Ravi Ranjan Kumar ◽  
Neelima D. Passi ◽  
D. K. Dhawan ◽  
Jaya Shukla ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Targeting

scholarly journals Development of a bispecific immune engager using a recombinant malaria protein

2021 ◽  
Vol 12 (4) ◽  
Author(s):  
Mie A. Nordmaj ◽  
Morgan E. Roberts ◽  
Emilie S. Sachse ◽  
Robert Dagil ◽  
Anne Poder Andersen ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Immune Evasion ◽  
Blood Cells ◽  
Xenograft Model ◽  
Cancer Targeting ◽  
Single Chain Variable Fragment ◽  
Single Chain ◽  
Conjugation System ◽  
Immune Mediated

AbstractAs an immune evasion and survival strategy, the Plasmodium falciparum malaria parasite has evolved a protein named VAR2CSA. This protein mediates sequestration of infected red blood cells in the placenta through the interaction with a unique carbohydrate abundantly and exclusively present in the placenta. Cancer cells were found to share the same expression of this distinct carbohydrate, termed oncofetal chondroitin sulfate on their surface. In this study we have used a protein conjugation system to produce a bispecific immune engager, V-aCD3, based on recombinant VAR2CSA as the cancer targeting moiety and an anti-CD3 single-chain variable fragment linked to a single-chain Fc as the immune engager. Conjugation of these two proteins resulted in a single functional moiety that induced immune mediated killing of a broad range of cancer cells in vitro and facilitated tumor arrest in an orthotopic bladder cancer xenograft model.

Importance of local glycan heterogeneity for in vivo cancer targeting

2021 ◽  
pp. 153089
Author(s):  
Ivan Smirnov ◽  
Igor Nasibullin ◽  
Almira Kurbangalieva ◽  
Katsunori Tanaka
Keyword(s):  
Cancer Targeting ◽  
Glycan Heterogeneity

Mussel-Derived, Cancer-Targeting Peptide as pH-Sensitive Prodrug Nanocarrier

2019 ◽  
Vol 11 (27) ◽  
pp. 23948-23956 ◽  
Author(s):  
Yue Ma ◽  
Peiyan He ◽  
Xiaohua Tian ◽  
Guanglei Liu ◽  
Xiaowei Zeng ◽  
...  
Keyword(s):  
Ph Sensitive ◽  
Cancer Targeting ◽  
Targeting Peptide

Combined Multi-Target Molecular Ultrasonography and Photothermal Therapy Using Cancer Targeting Gold Nano Rod Probes

2008 ◽  
Author(s):  
Dar-Bin Shieh ◽  
An An Ding ◽  
Ya-Na Wu ◽  
Ying-Yi Chen ◽  
Churng-Ren Chris Wang ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Cancer Targeting

Surface-engineered dendrimers for dual drug delivery: A receptor up-regulation and enhanced cancer targeting strategy

2008 ◽  
Vol 16 (10) ◽  
pp. 758-772 ◽  
Author(s):  
Rakesh Kumar Tekade ◽  
Tathagata Dutta ◽  
Abhishek Tyagi ◽  
Alok Chandra Bharti ◽  
Bhudev Chandra Das ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Targeting ◽  
Targeting Strategy ◽  
Dual Drug
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