Cancer Cell Photothermolysis and Gold Nanorod Surface Plasmons

2011 ◽  
pp. 54-70
Biomaterials ◽  
2010 ◽  
Vol 31 (14) ◽  
pp. 4104-4112 ◽  
Author(s):  
Cheng-Lung Chen ◽  
Ling-Ru Kuo ◽  
Ching-Lin Chang ◽  
Yeu-Kuang Hwu ◽  
Cheng-Kuang Huang ◽  
...  

2015 ◽  
Vol 3 (26) ◽  
pp. 5189-5196 ◽  
Author(s):  
Hui Hou ◽  
Limei Chen ◽  
Haili He ◽  
Lizhen Chen ◽  
Zhenlu Zhao ◽  
...  

Fine-tuning the LSPR response of Au nanorod–polyaniline core–shell nanoparticles can achieve high photothermal efficiency and stability for cancer cell ablation.


2019 ◽  
Author(s):  
Linyang Fan ◽  
Minzhi Zhao

AbstractGastric Cancer (GC) is one of the most serious cancers with high incidence and mortality all over the world. Chemotherapy hadn’t led to desirable effect and targeted therapy brings about a new stage to cancer treatment. Ramucirumab is the first FDA-approved therapy for advanced gastric cancer. It is well known that gold nanorod, a nontoxic biocompatible nanomaterial, is an especially promising candidate for cancer theranostic. In this study, Ramucirumab (Ab) were first modified by gold nanoparticles to enhance uptake efficiency. The simple Nano-delivery system had taken perfect aggregation effect in vivo even better than 5-fold Ab treatment. Gold nanomaterials, especially gold nanorod (AuNR), could induce direct cytotoxic effect to cancer cell in the presence of Ab, while Ab or gold nanoparticle themselves couldn’t lead to such direct killing effect even at an extremely high concentration. Proteomic and transcriptomic analyses revealed this direct cytotoxicity derived predominantly from Ab-mediated phagocytose, and the high affinity receptor for Fc gamma CD64 showed differential up-regulation only in gastric cancer cell treated by these nanodrugs compared with Ab, especially for AuNR group. This was the first time to discover that nanoparticle could induce regulation of immune related pathways and Fcγ receptor in the target cancer cell. Simplified and powerful designs of smart nanoparticles are highly desired for clinical. The dramatic enhancement of Ab accumulation with simple composition, combined with direct cytotoxic effect specific to cancer cells brought perfect therapeutic effects in vivo than Ab, which would promote further clinical application of gold nanorod in the diagnosis and therapeutics of gastric cancer.Abstract Figure


2010 ◽  
Vol 13 (7) ◽  
pp. 2749-2758 ◽  
Author(s):  
Chung-Hao Wang ◽  
Chia-Wei Chang ◽  
Ching-An Peng

2021 ◽  
Author(s):  
Thanh Lam Bui ◽  
Ngoc Thanh Ho ◽  
Xuan Vuong Thi Thanh Ho ◽  
Dinh Nghi Ngo ◽  
Soon Hyuk Lim ◽  
...  

Optical properties of anisotropic gold nanorod arrays inside anodic aluminium oxide substrates enhance the longitudinal absorption intensities and the hyperthermia cancer cell killing at 42.1 °C under photothermal laser exposures...


ACS Nano ◽  
2018 ◽  
Vol 12 (9) ◽  
pp. 9279-9290 ◽  
Author(s):  
Yue Wu ◽  
Moustafa R. K. Ali ◽  
Bin Dong ◽  
Tiegang Han ◽  
Kuangcai Chen ◽  
...  

2015 ◽  
Vol 57 ◽  
pp. 189-201 ◽  
Author(s):  
Jay Shankar ◽  
Cecile Boscher ◽  
Ivan R. Nabi

Spatial organization of the plasma membrane is an essential feature of the cellular response to external stimuli. Receptor organization at the cell surface mediates transmission of extracellular stimuli to intracellular signalling molecules and effectors that impact various cellular processes including cell differentiation, metabolism, growth, migration and apoptosis. Membrane domains include morphologically distinct plasma membrane invaginations such as clathrin-coated pits and caveolae, but also less well-defined domains such as lipid rafts and the galectin lattice. In the present chapter, we will discuss interaction between caveolae, lipid rafts and the galectin lattice in the control of cancer cell signalling.


2010 ◽  
Vol 34 (8) ◽  
pp. S50-S50
Author(s):  
Xiaoyan Pan ◽  
Xinmei Zhou ◽  
Guangtao Xu ◽  
Lingfen Miao ◽  
Shuoru Zhu

Sign in / Sign up

Export Citation Format

Share Document