Melatonin and DNA Protection

2011 ◽  
pp. 497-506
Keyword(s):  
Dna Protection

Mitochondriotropic action and DNA protection: Interactions between phenolic acids and enzymes

2019 ◽  
Vol 34 (1) ◽  
Author(s):  
Tatiane Silva Abreu ◽  
Mariana Aparecida Braga ◽  
Anderson Assaid Simão ◽  
Marcus Vinicius Cardoso Trento ◽  
Mateus Willian de Faria Eleutério ◽  
...  
Keyword(s):  
Phenolic Acids ◽  
Dna Protection

scholarly journals The Anti-Ageing and Whitening Potential of a Cosmetic Serum Containing 3-O-ethyl-l-ascorbic Acid

Life ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 406
Author(s):  
Nicola Zerbinati ◽  
Sabrina Sommatis ◽  
Cristina Maccario ◽  
Serena Di Francesco ◽  
Maria Chiara Capillo ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Dermal Fibroblasts ◽  
Melanin Content ◽  
Dna Protection ◽  
Melanin Pigmentation ◽  
Intrinsic Factors ◽  
Reconstructed Human Epidermis ◽  
Solar Ultraviolet ◽  
Damage Marker ◽  
Extrinsic And Intrinsic Factors

Skin ageing has many manifestations such as wrinkles, dryness, hyperpigmentation, and uneven skin tone. Extrinsic and intrinsic factors, especially solar ultraviolet light (UVB), contribute to skin ageing; its main features are brown spots, alterations in melanin pigmentation, and a decrease in collagen and hyaluronic acid linked to oxidative stress. Several studies showed that topical products containing ingredients with antioxidant activity can reduce oxidative damage; to provide a maximum anti-ageing effect to the skin, topical products can combine various ingredients. C-SHOT SERUM contains a combination of two molecules with a proven anti-ageing activity: a high percentage (30%) of a more stable vitamin C derivative, 3-O-ethyl-l-ascorbic acid, and lactic acid (1%). The product showed a high biocompatibility, assessed through an MTT assay on keratinocytes and on Reconstructed Human Epidermis (RHE, SkinEthic); the anti-ageing activity was demonstrated on human dermal fibroblasts and keratinocytes by a statistically significant increase in collagen production and a reduction of a UVB-induced DNA damage marker (γ-H2AX histone), indicating DNA protection. Moreover, a depigmenting activity, shown by a highly significant decrease in melanin content on treated Reconstructed Human Pigmented Epidermis (RHPE), was assessed. According to the data of our study, the tested product contrasts the effect of skin ageing and irregular pigmentation due to the physiological decline of the skin.

scholarly journals The nocturnal bottleneck and the evolution of activity patterns in mammals

2013 ◽  
Vol 280 (1765) ◽  
pp. 20130508 ◽  
Author(s):  
Menno P. Gerkema ◽  
Wayne I. L. Davies ◽  
Russell G. Foster ◽  
Michael Menaker ◽  
Roelof A. Hut
Keyword(s):  
Energy Balance ◽  
Activity Patterns ◽  
Protection System ◽  
Dna Protection ◽  
Light Detection ◽  
Dominant Taxon ◽  
Visual Systems ◽  
Daytime Activity ◽  
Mammalian Lineage ◽  
The Status

In 1942, Walls described the concept of a ‘nocturnal bottleneck’ in placental mammals, where these species could survive only by avoiding daytime activity during times in which dinosaurs were the dominant taxon. Walls based this concept of a longer episode of nocturnality in early eutherian mammals by comparing the visual systems of reptiles, birds and all three extant taxa of the mammalian lineage, namely the monotremes, marsupials (now included in the metatherians) and placentals (included in the eutherians). This review describes the status of what has become known as the nocturnal bottleneck hypothesis, giving an overview of the chronobiological patterns of activity. We review the ecological plausibility that the activity patterns of (early) eutherian mammals were restricted to the night, based on arguments relating to endothermia, energy balance, foraging and predation, taking into account recent palaeontological information. We also assess genes, relating to light detection (visual and non-visual systems) and the photolyase DNA protection system that were lost in the eutherian mammalian lineage. Our conclusion presently is that arguments in favour of the nocturnal bottleneck hypothesis in eutherians prevail.

scholarly journals Myricitrin and bioactive extract ofAlbizia amaraleaves: DNA protection and modulation of fertility and antioxidant-related genes expression

2016 ◽  
Vol 54 (11) ◽  
pp. 2404-2409 ◽  
Author(s):  
Mona El Said Kassem ◽  
Lamya Fawzy Ibrahim ◽  
Sameh Reda Hussein ◽  
Reham El-Sharawy ◽  
Mohamed Amin El-Ansari ◽  
...  
Keyword(s):  
Dna Protection ◽  
Genes Expression

DNA-protection and antioxidant properties of fermentates fromBacillus amyloliquefaciensB-1895 andBacillus subtilisKATMIRA1933

2015 ◽  
Vol 61 (6) ◽  
pp. 549-554 ◽  
Author(s):  
E.V. Prazdnova ◽  
V.A. Chistyakov ◽  
M.N. Churilov ◽  
M.S. Mazanko ◽  
A.B. Bren ◽  
...  
Keyword(s):  
Antioxidant Properties ◽  
Dna Protection

Analysis of DNA protection, interaction and antimicrobial activity of isatin derivatives

2019 ◽  
Vol 122 ◽  
pp. 1271-1278 ◽  
Author(s):  
Mohamed Abdulhamid Ganim ◽  
Mehmet Cengiz Baloglu ◽  
Aysenur Aygun ◽  
Yasemin Celik Altunoglu ◽  
Hakan Sezgin Sayiner ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Dna Protection ◽  
Isatin Derivatives
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