History of Manufactured Gas and Coal-Tar Activities

2011 ◽  
pp. 3-53
Keyword(s):  
Coal Tar ◽  
History Of

A Brief History of Psoriasis Management in Canada

2020 ◽  
Vol 24 (3) ◽  
pp. 273-277
Author(s):  
Khalad Maliyar ◽  
Patrick Fleming ◽  
Boluwaji Ogunyemi ◽  
Charles Lynde
Keyword(s):  
20Th Century ◽  
Coal Tar ◽  
Historical Review ◽  
Chronic Inflammatory Disease ◽  
Biologic Therapies ◽  
First Line ◽  
Revolutionary Change ◽  
Clinical Presentations ◽  
History Of ◽  
The 19Th Century

Psoriasis is a chronic, inflammatory disease with a varying degree of clinical presentations. Managing psoriasis has always been arduous due to its chronicity and its propensity to relapse. Prior to the development of targeted biologic therapies, there were few effective treatments for psoriasis. Ancient psoriasis therapies included pinetar, plant extracts, psychotherapy, arsenic, and ammoniated mercury. In the 19th century, chrysarobin was developed. Then, in the early half of the 20th century, anthralin and coal tar were in widespread use. In the latter half of the 20th century, treatments were limited to topical first-line therapies, systemic drugs, and phototherapy. However, as the treatment of psoriasis has undergone a revolutionary change with the development of novel biologic therapies, patients with moderate to severe psoriasis have been able to avail therapies with high efficacy and durability along with an acceptable safety profile. This article is a brief historical review of the management of psoriasis prior to the inception of biologics and with the development of novel biologic therapies.

Dyes and Dyeing 1775–1860

1963 ◽  
Vol 1 (3) ◽  
pp. 265-279 ◽  
Author(s):  
C. M. Mellor ◽  
D. S. L. Cardwell
Keyword(s):  
Coal Tar ◽  
Medical Science ◽  
Textile Mills ◽  
Early Suggestion ◽  
Intimate Association ◽  
Long Time ◽  
History Of ◽  
Textile Industries ◽  
James Thomson ◽  
The Town

The history of the dyestuffs industry during the period 1775–1860 is interesting for three reasons. In the first place it was in connection with the manufacture of synthetic dyestuffs, begun in 1856, that the industrial research laboratory and the organization scientist first unmistakably appeared in the last decades of the nineteenth century. Secondly, there are the enigmas of W. H. Perkin, the man who discovered and manufactured the first coal-tar colours, but who retired somewhat abruptly from the industry in 1874: just after the synthesis of alizarine. Thirdly, the dyestuffs industry was in intimate association with the textile industries which had for a long time been subject to frequent radical scientific and technological innovation. Among the most important of these we may mention John Smeaton's classic paper of 1759 on the maximum work obtainable from a given fall of water: a problem important not only for the abstract science of mechanics, but also for the design of waterwheels—the main source of power for the early textile mills. (The waterwheel was not, during the eighteenth century, the epitome of the quaint and picturesque: it was in the van of scientific and technical progress.) Again, the textile industries were quick to employ the Watt rotative engine; previously a two cylinder Newcomen engine had been tried out. Bleaching powders, based on Scheele's discovery of chlorine and its properties, were rapidly adopted: in this context one cannot help contrasting the indifference of medical science to Davy's early suggestion of using nitrous oxide as an anaesthetic; or Faraday's comment in 1818 on the anaesthetic power of sulphuric ether. The textile industries saw, over this period, a rapid succession of new machines, the pace of invention being so hot that in 1832 Charles Babbage reported that machines became obsolete long before they wore out. A Salford cotton mill was the first industrial establishment to use gas lighting: James Thomson, calico printer, introduced gas lighting to the town of Clitheroe when he installed it in his works. And there were many other important technical and scientific innovations. It was to supply these industries, so well accustomed to change, that the synthetic coal-tar dyestuffs were introduced from 1856 onwards. It is interesting that, so far as we can see, the appearance of these synthetic dyestuffs was the last in the series of major innovations in the textiles and related industries: at least until recent times.

Indeterminate Cell Histiocytosis

2003 ◽  
Vol 127 (6) ◽  
pp. 748-751 ◽  
Author(s):  
Rodolfo Rodríguez-Jurado ◽  
Helena Vidaurri-de la Cruz ◽  
Carola Durán-Mckinster ◽  
Ramón Ruíz-Maldonado
Keyword(s):  
Skin Biopsy ◽  
Conservative Management ◽  
Adolescent Girl ◽  
Coal Tar ◽  
S100 Protein ◽  
Topical Steroid ◽  
Accurate Diagnosis ◽  
Diffuse Infiltration ◽  
Birbeck Granules ◽  
History Of

Abstract Indeterminate cell histiocytosis is a rare disorder involving altered homing mechanisms of the cutaneous histiocytic/dendritic system. It has been described predominantly in adults, with less than a dozen cases in children. A 13-year-old adolescent girl presented with a 4-year history of asymptomatic erythematous nodules and plaques, measuring from 1 to 5 cm in diameter, that were located mainly on the trunk and proximal portions of her limbs. A skin biopsy showed dermal diffuse infiltration of histiocytic cells. Most of the histiocytic cells were strongly positive for S100 protein. No Birbeck granules were found. Treatment with topical steroid was ineffective. After 6 months of pure coal tar and 5% 5-fluorouracil cream, an almost total clearing of lesions was observed. An accurate diagnosis of this condition is mandatory in order to avoid unnecessary treatments. Conservative management is also discussed.

scholarly journals VIII. Contributions towards the history of the colouring matters derived from coal-tar

1863 ◽  
Vol 12 ◽  
pp. 647-648 ◽  
Keyword(s):  
Boiling Point ◽  
Large Scale ◽  
Coal Tar ◽  
Fractional Distillation ◽  
Commercial Product ◽  
Previous Note ◽  
Starting Point ◽  
History Of

In a previous Note I have shown that the red colouring matter cannot be obtained from normal aniline by the action of the agents usually employed for the preparation of this colour on a large scale. This observation naturally induced me to seek for the constituent in the commercial aniline which gives rise to the formation of aniline-red. I have already remarked that the commercial product which is best suited for the manufacture of the red colour, boils at a temperature appreciably higher than the boiling-point of normal aniline. The idea presented itself of submitting this substance to a fractional distillation, or else of effecting a methodical separation of the hydrocarbons which constitute the starting-point for the manufacture of the bases; but, as is well known, these processes are difficult and tedious, and there is little chance of success unless the operation be performed on a very large scale.

scholarly journals Psoriasis - A Report of Disease Mimicry

2020 ◽  
Vol 18 (2) ◽  
Author(s):  
Mohd Shaiful Ehsan Shalihin ◽  
Mohd Aizuddin Abd Rahman
Keyword(s):  
Case Report ◽  
Joint Pain ◽  
Coal Tar ◽  
Skin Condition ◽  
Line Treatment ◽  
First Line ◽  
Recent Exposure ◽  
History Of ◽  
Acute Condition ◽  
First Line Treatment

Introduction: Psoriasis is a chronic, noncontagious, multifactorial inflammatory skin condition that has several subtypes. Therefore, prior to actual diagnosis, it may mimics other similar illnesses. In acute condition, it typically presents with erythroderma macules associated with pain and itchiness rather than  hypopigmented and numbness lesions that supposedly occurs in post-treatment or post-acute phase, rather than as initial presentation. Case report: We report a case of 18-year-old girl, who presented with nonspecific localized hypopigmented rash over her forehead and scalp associated with numbness for three weeks duration. She had no itchiness or rashes elsewhere. She had no history of atopy or recent exposure to new cosmetics. She had no joint pain or hair loss. She had no recent contact with anyone with similar lesion. No significant similar history among family members. Clinically, there is reduced in both soft touch and pin-prick sensation over affected areas. We refer this case to dermatologist with possibility of leprosy in view of her reduced sensation over the lesion. To our surprise, the skin biopsy revealed supportive points towards psoriasis. She responds well towards coal tar and topical corticosteroids-the first line treatment of psoriasis. Her numbness has also resolved. This case highlights that psoriasis do presents with localized numbness in which its diagnosis should be take into consideration before confining the disease towards leprosy only.

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