Complex forms and form-finding

2010 ◽  
pp. 179-179
Keyword(s):  
Form Finding ◽  
Complex Forms

scholarly journals BLOOM: materialising computational workflows

2019 ◽  
Author(s):  
Michail Georgiou ◽  
Odysseas Georgiou
Keyword(s):  
Design Process ◽  
Form Finding ◽  
Ongoing Research ◽  
Complex Forms

The paper presents ongoing research, aiming towards affordability of complex forms in architecture. The research supports that the above objective can be approached by re-examining and integrating materiality and form-finding techniques in computational feedback models. Within the above framework, a computationally enhanced design process is proposed and presented through a realised case study.

Organization of the Pellicle and the Muciferous Glands in Euglena Gracilis

1970 ◽  
Vol 28 ◽  
pp. 104-105
Author(s):  
Hilton H. Mollenhauer ◽  
W. Evans
Keyword(s):  
Plasma Membrane ◽  
Euglena Gracilis ◽  
Complex Forms ◽  
Secondary Periodicity

The pellicular structure of Euglena gracilis consists of a series of relatively rigid strips (Fig. 1) composed of ridges and grooves which are helically oriented along the cell and which fuse together into a common junction at either end of the cell. The strips are predominantly protein and consist in part of a series of fibers about 50 Å in diameter spaced about 85 Å apart and with a secondary periodicity of about 450 Å. Microtubules are also present below each strip (Fig. 1) and are often considered as part of the pellicular complex. In addition, there may be another fibrous component near the base of the pellicle which has not yet been very well defined.The pellicular complex lies underneath the plasma membrane and entirely within the cell (Fig. 1). Each strip of the complex forms an overlapping junction with the adjacent strip along one side of each groove (Fig. 1), in such a way that a certain amount of sideways movement is possible between one strip and the next.

Making gender visible in family business: past and present

2012 ◽  
Vol 13 (1) ◽  
Author(s):  
Paloma Fernández Pérez ◽  
Eleanor Hamilton
Keyword(s):  
Family Business ◽  
Family Firms ◽  
Business Leadership ◽  
Legal Rules ◽  
Developed Economies ◽  
The Family ◽  
Interdisciplinary Synthesis ◽  
Complex Forms ◽  
Rules Of The Game

This  study  contributes  to  developing  our understanding of gender and family business. It draws on studies from the business history and management literatures and provides an interdisciplinary synthesis. It illuminates the role of women and their participation in the entrepreneurial practices of the family and the business. Leadership is introduced as a concept to examine the roles of women and men in family firms, arguing that concepts used  by  historians or economists like ownership and management have served to make women ‘invisible’, at least in western developed economies in which owners and managers have been historically due to legal rules  of  the  game  men,  and  minoritarily women. Finally, it explores gender relations and  the  notion  that  leadership  in  family business  may  take  complex  forms  crafte within constantly changing relationships.

How to grow a self: development of the self in a Bayesian brain

2019 ◽  
Author(s):  
Mateusz Wozniak
Keyword(s):  
Conceptual Development ◽  
Human Life ◽  
Predictive Coding ◽  
Body Representation ◽  
Developmental Trajectory ◽  
The Self ◽  
Learning Mechanisms ◽  
Bayesian Brain ◽  
Third Person ◽  
Complex Forms

The last two decades have brought several attempts to explain the self as a part of the Bayesian brain, typically within the framework of predictive coding. However, none of these attempts have looked comprehensively at the developmental aspect of self-representation. The goal of this paper is to argue that looking at the developmental trajectory is crucial for understanding the structure of an adult self-representation. The paper argues that the emergence of the self should be understood as an instance of conceptual development, which in the context of a Bayesian brain can be understood as a process of acquisition of new internal models of hidden causes of sensory input. The paper proposes how such models might emerge and develop over the course of human life by looking at different stages of development of bodily and extra-bodily self-representations. It argues that the self arises gradually in a series of discrete steps: from first-person multisensory representations of one’s body to third-person multisensory body representation, and from basic forms of the extended and social selves to progressively more complex forms of abstract self-representation. It discusses how each of them might emerge based on domain-general learning mechanisms, while also taking into account the potential role of innate representations. Finally it suggests how the conceptual structure of self-representation might inform the debate about the structure of self-consciousness.

Complex forms of the ethnic identity

2020 ◽  
Vol 4 (2) ◽  
pp. 75-89
Author(s):  
J.S. Zamaraeva ◽  
Keyword(s):  
Ethnic Identity ◽  
Complex Forms

Das Werk als Entgrenzung. : Werkkomplex und Dynamik des Gesamtwerks

2021 ◽  
Vol 31 (1) ◽  
pp. 139-154
Author(s):  
Svetlana Efimova
Keyword(s):  
Dynamic Structure ◽  
Intermediate Stage ◽  
Literary Work ◽  
Theoretical Research ◽  
Semantic Composition ◽  
Complex Forms ◽  
Special Relevance ◽  
Reception Side

Abstract Im Kontext des neu aufgekommenen theoretischen Interesses für die Werkkategorie wird überwiegend das ,Einzelwerk‘ fokussiert. Im vorliegenden Aufsatz wird das heuristische Potenzial des Konzepts ,Gesamtwerk‘ als ein anderer Teil der Werkkategorie herausgearbeitet. Neben dem üblichen Aspekt eines ,Lebenswerks‘ schließt das Gesamtwerk vielfältige Werkkomplexe und Werkgruppierungen ein, die auf Produktions- oder Rezeptionsseite entstehen. Analysiert werden feste und variable Anordnungen, Ab- und Entgrenzungen zwischen Einzelwerken eines Autors, die das Gesamtwerk zu einem dynamischen Gefüge machen. Ein Werkkomplex bildet eine Zwischenstufe und ein Bindeglied zwischen ,Einzelwerk‘ und ,Gesamtwerk‘. Daher besitzt er eine besondere Relevanz für die semantische Zusammensetzung der Werkkategorie als Trias, deren Teile sich aufeinander beziehen: Opus – Werkkomplex – Œuvre.The newly arisen theoretical research on the literary work category focuses mainly on the ,single work‘. This paper argues for the heuristic potential of the ,oeuvre‘ as another part of the work category. In addition to the usual aspect of a ,life’s work‘, the oeuvre includes diverse work complexes and work groupings that emerge on the production or reception side. The paper analyzes a dynamic structure of the oeuvre: fixed and variable arrangements, boundaries and dissolution of borders between single works by the same author. A work complex forms an intermediate stage and a link between ,single work‘ and ,oeuvre‘. It therefore has a special relevance for the semantic composition of the work category as a triad, the parts of which refer to each other: single work – work complex – oeuvre.

A comprehensive in silico study towards understanding the inhibitory mechanism of Lactoperoxidase by Dapsone and Propofol

2020 ◽  
Vol 16 ◽  
Author(s):  
Rameez Jabeer Khan ◽  
Rajat Kumar Jha ◽  
Gizachew Muluneh Amera ◽  
Jayaraman Muthukumaran ◽  
Rashmi Prabha Singh ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Md Simulation ◽  
Binding Free Energy ◽  
Protoporphyrin Ix ◽  
Md Simulations ◽  
Prosthetic Group ◽  
Drug Molecules ◽  
Group A ◽  
Complex Forms ◽  
Covalently Linked

Introduction: Lactoperoxidase (LPO) is a member of mammalian heme peroxidase family and is an enzyme of innate immune system. It possesses a covalently linked heme prosthetic group (a derivative of protoporphyrin IX) in its active site. LPO catalyzes the oxidation of halides and pseudohalides in the presence of hydrogen peroxide (H2O2) and shows a broad range of antimicrobial activity. Methods: In this study, we have used two pharmaceutically important drug molecules, namely dapsone and propofol, which are earlier reported as potent inhibitors of LPO. Whereas the stereochemistry and mode of binding of dapsone and propofol to LPO is still not known because of the lack of the crystal structure of LPO with these two drugs. In order to fill this gap, we utilized molecular docking and molecular dynamics (MD) simulation studies of LPO in native and complex forms with dapsone and propofol. Results: From the docking results, the estimated binding free energy (ΔG) of -9.25 kcal/mol (Ki = 0.16 μM) and -7.05 kcal/mol (Ki = 6.79 μM) was observed for dapsone, and propofol, respectively. The standard error of Auto Dock program is 2.5 kcal/mol; therefore, molecular docking results alone were inconclusive. Conclusion: To further validate the docking results, we performed MD simulation on unbound, and two drugs bounded LPO structures. Interestingly, MD simulations results explained that the structural stability of LPO-Propofol complex was higher than LPO-Dapsone complex. The results obtained from this study establish the mode of binding and interaction pattern of the dapsone and propofol to LPO as inhibitors.

Access to Justice for Ethno-Racial Psychiatric Consumer/Survivors in Ontario

2011 ◽  
Vol 29 ◽  
pp. 127 ◽  
Author(s):  
Ruby Dhand
Keyword(s):  
Mental Health ◽  
Institutional Racism ◽  
Access To Justice ◽  
Complex Needs ◽  
Troubles Mentaux ◽  
Inappropriate Care ◽  
Race Ethnicity ◽  
Complex Forms ◽  
Face Complex ◽  
Legal Barriers

Ethno-racial psychiatric consumer/survivors face complex forms of discrimination as a result of the culture specific stigmatization of mental health disabilities, institutional racism and culturally inappropriate care. In an effort to achieve better access to justice for ethno-racial communities, we must strive to understand their complex needs, perspectives and conceptions of mental health. Thus, I identify and critique the legal barriers, which are perceived to differentially affect ethno-racial psychiatric consumer/survivors in Ontario, through an analysis of the Consent and Capacity Board [CCB]. I propose the hypothesis that factors such as race, ethnicity, culture, poverty and social exclusion are not fully addressed by the CCB. I use data collected from interviews with stakeholders to reveal the procedural, structural/systemic and discretionary barriers faced by ethno-racial psychiatric consumer/survivors within the CCB’s pre-hearing, hearing and post-hearing processes, along with recommendations to address these barriers.Les consommateurs/survivants de la psychiatrie ethnoraciale doivent surmonter des formes complexes de discrimination en raison de la stigmatisation culturelle des troubles mentaux, du racisme institutionnel et des soins culturellement inappropriés. Pour améliorer l’accès à la justice des collectivités ethnoraciales, nous devons nous efforcer de comprendre leurs besoins complexes, leurs perspectives et leurs conceptions de la santé mentale. Dans le présent travail, je relève et critique les obstacles juridiques, qui sont perçus comme touchant différemment les consommateurs/survivants de la psychiatrie ethnoraciale en Ontario, en effectuant une analyse des travaux de la Commission du consentement et de la capacité (la « CCC »). J’émets l’hypothèse que la CCC ne prend pas pleinement en compte des facteurs comme la race, l’ethnicité, la culture, la pauvreté et l’exclusion sociale. J’utilise des données provenant d’entrevues avec des parties prenantes pour illustrer les obstacles procéduraux, structurels/systémiques et discrétionnaires auxquels font face les consommateurs/survivants de la psychiatrie ethnoraciale lors des audiences préparatoires et des audiences de la CCC et dans le cadre des processus suivis par la CCC après les audiences, et je formule des recommandations visant à surmonter ces obstacles.

Self-organization

2018 ◽  
Author(s):  
Stuart P. Wilson
Keyword(s):  
Large Deviation ◽  
Natural World ◽  
Self Organization ◽  
Global Order ◽  
Deterministic Systems ◽  
Working Definition ◽  
Complex Forms ◽  
Robust To Noise ◽  
Organizing Principles ◽  
Self Organizing

Self-organization describes a dynamic in a system whereby local interactions between individuals collectively yield global order, i.e. spatial patterns unobservable in their entirety to the individuals. By this working definition, self-organization is intimately related to chaos, i.e. global order in the dynamics of deterministic systems that are locally unpredictable. A useful distinction is that a small perturbation to a chaotic system causes a large deviation in its trajectory, i.e. the butterfly effect, whereas self-organizing patterns are robust to noise and perturbation. For many, self-organization is as important to the understanding of biological processes as natural selection. For some, self-organization explains where the complex forms that compete for survival in the natural world originate from. This chapter outlines some fundamental ideas from the study of simulated self-organizing systems, before suggesting how self-organizing principles could be applied through biohybrid societies to establish new theories of living systems.

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