Adhesion Molecules in Atrial Fibrillation

2010 ◽  
pp. 409-427
Author(s):  
Matthias Hammw√∂hner ◽  
Alicja Bukowska ◽  
R√ºdiger Braun-Dullaeus ◽  
Andreas Goette
Keyword(s):  
Atrial Fibrillation ◽  
Adhesion Molecules

scholarly journals Hemodynamic and endothelium-protective effects of β-adrenoblockers in patients with coronary heart disease complicated by chronic heart failure and atrial fibrillation

2010 ◽  
Vol 1 (1) ◽  
pp. 65-69
Author(s):  
A. N Zakirova ◽  
E. R Abdyukova ◽  
N. E Zakirova
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Heart Disease ◽  
Chronic Heart Failure ◽  
Adhesion Molecules ◽  
Cellular Adhesion ◽  
Clinical State ◽  
Term Therapy ◽  
Protective Effects ◽  
Metoprolol Tartrate

Aim. To elucidate effect of b-adrenoblockers on remodeling of myocardium and adhesive function of endothelium in with ischemic heart disease with chronic heart failure (CHF) and addition of atrial fibrillation (AF). Material and methods. We included into the study 77 patients with functional class II–III CHF and AF of ischemic genesis randomized in 2 groups, In group 1 were included 40 patients who during 24 weeks used carvedilol at the background of basic therapy, in group 2–37 patients receiving metoprolol tartrate. In the work we used clinico-instrumental (echocardiography, test with 60 minute walk), immunoenzymatic (soluble intercellular adhesion molecules (sVCAM, SE – selectin) methods of investigation. Results. Application of both BAB improved clinical state and physical working capacity of patients with CHF and AF. Carvedilol more significantly than metoprolol tartrate prevented remodeling of myocardium, inhibited expression of cellular adhesion molecules. Levels of sE-selectin and VCAM-1 decreased under action of carvedilol. Conclusion. Carvedilol in long term therapy of CHF with AF exerts substantial influence on adhesive function of endothelium and improves hemodynamics.

Increased levels of adhesion molecules and monocyte chemoattractant protein-1 during persistent atrial fibrillation

Heart Rhythm ◽  
2005 ◽  
Vol 2 (5) ◽  
pp. S21
Author(s):  
Matthias Hammwoehner ◽  
Jutta Dierkes ◽  
Annelore Ittenson ◽  
Alicja Bukowska ◽  
Uwe Lendeckel ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Adhesion Molecules ◽  
Persistent Atrial Fibrillation ◽  
Monocyte Chemoattractant Protein 1 ◽  
Monocyte Chemoattractant ◽  
Monocyte Chemoattractant Protein

Segregation of cell adhesion molecules into membrane microdomains facilitates leukocyte-endothelial interactions

1995 ◽  
Vol 53 ◽  
pp. 780-781
Author(s):  
S.L. Erlandsen
Keyword(s):  
Cell Surface ◽  
Adhesion Molecules ◽  
Colloidal Gold ◽  
High Spatial Resolution ◽  
Low Voltage ◽  
Cellular Adhesion ◽  
Membrane Microdomains ◽  
Immunogold Label ◽  
Cellular Adhesion Molecules ◽  
Electron Detection

Cells interact with their extracellular environments by means of a variety of cellular adhesion molecules (CAM) and surface ligands. In many instances, CAMs interact in a sequential temporal fashion which suggests that these adhesion molecules may occupy or be polarized to various membrane microdomains on the cell surface. Detection of CAMs can be accomplished by a variety of methods including immunofluorescent microscopy and flow cytometry, and by the use of immunocytochemical markers (i.e. colloidal gold) in electron microscopy. The development of high resolution field emission SEM in the mid 1980's and the Autrata modification of the YAG detector for backscatter electron detection at low voltage has greatly facilitated the recognition of colloidal gold probes for detection of surface CAMs. Low voltage FESEM with Bse imaging provides increased resolution of cell surface topography (~3nm at 3-4 keV) which can be observed in 3-dimensions, and simultaneously permits detection/high spatial resolution of immunogold label by atomic number contrast.

Astrocytic adhesion molecules are increased in HIV-1-associated cognitive/motor complex

1997 ◽  
Vol 23 (3) ◽  
pp. 83-92 ◽  
Author(s):  
D. Seilhean ◽  
A. Dzia-Lepfoundzou ◽  
V. Sazdovitch ◽  
B. Cannella ◽  
C. S. Raine ◽  
...  
Keyword(s):  
Adhesion Molecules ◽  
Motor Complex ◽  
Hiv 1
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