2020 ◽  
Vol 63 (10) ◽  
pp. 3311-3325
Author(s):  
Brittany L. Perrine ◽  
Ronald C. Scherer

Purpose The goal of this study was to determine if differences in stress system activation lead to changes in speaking fundamental frequency, average oral airflow, and estimated subglottal pressure before and after an acute, psychosocial stressor. Method Eighteen vocally healthy adult females experienced the Trier Social Stress Test (TSST) to activate the hypothalamic–pituitary–adrenal axis. The TSST includes public speaking and performing mental arithmetic in front of an audience. At seven time points, three before the stressor and four after the stressor, the participants produced /pa/ repetitions, read the Rainbow Passage, and provided a saliva sample. Measures included (a) salivary cortisol level, (b) oral airflow, (c) estimated subglottal pressure, and (d) speaking fundamental frequency from the second sentence of the Rainbow Passage. Results Ten of the 18 participants experienced a hypothalamic–pituitary–adrenal axis response to stress as indicated by a 2.5-nmol/L increase in salivary cortisol from before the TSST to after the TSST. Those who experienced a response to stress had a significantly higher speaking fundamental frequency before and immediately after the stressor than later after the stressor. No other variable varied significantly due to the stressor. Conclusions This study suggests that the idiosyncratic and inconsistent voice changes reported in the literature may be explained by differences in stress system activation. In addition, laryngeal aerodynamic measures appear resilient to changes due to acute stress. Further work is needed to examine the influence of other stress systems and if these findings hold for dysphonic individuals.


2020 ◽  
Vol 127 (12) ◽  
pp. 1651-1662
Author(s):  
Julia Brandt ◽  
Katharina Warnke ◽  
Silke Jörgens ◽  
Volker Arolt ◽  
Katja Beer ◽  
...  

AbstractDepression and coronary heart disease (CHD) are prevalent and often co-occurring disorders. Both have been associated with a dysregulated stress system. As a central element of the stress system, the FKBP5 gene has been shown to be associated with depression. In a prospective design, this study aims to investigate the association of FKBP5 with depressive symptoms in CHD patients. N = 268 hospitalized CHD patients were included. Depressive symptoms were measured using the Hospital Anxiety and Depression Scale (HADS-D) at four time points (baseline, and after 1 month, 6 months, and 12 months). The functional FKBP5 single-nucleotide polymorphism (SNP) rs1360780 was selected for genotyping. Linear regression models showed that a higher number of FKBP5 C alleles was associated with more depressive symptoms in CHD patients both at baseline (p = 0.015) and at 12-months follow-up (p = 0.025) after adjustment for confounders. Further analyses revealed that this effect was driven by an interaction of FKBP5 genotype with patients’ prior CHD course. Specifically, only in patients with a prior myocardial infarction or coronary revascularization, more depressive symptoms were associated with a higher number of C alleles (baseline: p = 0.046; 1-month: p = 0.026; 6-months: p = 0.028). Moreover, a higher number of C alleles was significantly related to a greater risk for dyslipidemia (p = .016). Our results point to a relevance of FKBP5 in the association of the two stress-related diseases depression and CHD.


2019 ◽  
Vol 136 ◽  
pp. 02030
Author(s):  
Chen Dong ◽  
Chen Ming ◽  
Cai Ouyang ◽  
Li Pengkun

The GRC formwork structural column adopts the factory-based vertical prefabrication production process, which can reduce the floor space, reduce the formwork loss, speed up the construction progress, promote the full decoration of the prefabricated building, and improve the efficiency of the assembly construction. major. In order to optimize the production process of prefabricated GRC formwork column, the overall stress system of GRC formwork structure is analyzed in the concrete pouring process, and the thickness of GRC formwork, the number of steel hoops and the GRC mode are considered. The influence of the shell cross-section size on the mechanical properties. The research results can provide reference for the optimization and design of prefabricated GRC formwork column production process.


2011 ◽  
Vol 383-390 ◽  
pp. 774-779
Author(s):  
Ye Min Guo ◽  
Lan Mei Wang ◽  
Rui Yong Xue

According to the requirements of measurement of plantar pressure and shear stress in the meantime, this thesis puts forward a plan to construct a new insole plantar pressure and shear stress system based on multifunction data acquisition modular and Lab VIEW. Then the hardware part and software part are designed and developed respectively. There are 3 sensors are arrayed at each measurement point, that means 3 sensors are assembled in 3 different directions of X,Y and Z . The piezoelectric ceramic type sensors are designed, manufactured and calibrated according to scientific methods. Meanwhile, the DAQ card is selected carefully. Of course, the software part is developed based on Lab VIEW. A series of tests are performed in order to validate the function of the measurement system. The results satisfy the anticipated design requirements. At last, the problems and application trend of the measurement system are predicted.


1959 ◽  
Vol 10 (4) ◽  
pp. 326-344 ◽  
Author(s):  
H. T. Jessop ◽  
C. Snell ◽  
I. M. Allison

The “frozen stress” techniques of photoelasticity can give a complete knowledge of the stress, system in a solid body, but the examination of the stresses requires more time and care than in corresponding flat plate tests. In tests on tubes with transverse circular holes, sponsored by The Royal Aeronautical Society, all practicable geometrical shapes are examined and the maximum stress is measured in tension, bending and torsion. The results are comprehensive and show the inadequacy of previous results. In all cases the maximum stress occurs inside the bore of the hole. The accuracy of all the graphs of stress concentration factors is better than five per cent.


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