Nuclear Imaging of the Vulnerable Plaque

2004 ◽  
pp. 129-144
Author(s):  
John Davies ◽  
Tim Fryer ◽  
Peter Weissberg ◽  
James Rudd ◽  
Jonathan Gillard
Keyword(s):  
Vulnerable Plaque ◽  
Nuclear Imaging

Nuclear imaging of the vulnerable plaque

2007 ◽  
pp. 303-312
Author(s):  
Sotirios Tsimikas ◽  
Jagat Narula
Keyword(s):  
Vulnerable Plaque ◽  
Nuclear Imaging

Targeting the vulnerable plaque: The evolving role of nuclear imaging

2005 ◽  
Vol 12 (2) ◽  
pp. 234-246 ◽  
Author(s):  
J DAVIES ◽  
J RUDD ◽  
T FRYER ◽  
P WEISSBERG
Keyword(s):  
Vulnerable Plaque ◽  
Nuclear Imaging

174 Myocardial perfusion by intravenous echo contrast and by nuclear imaging

1999 ◽  
Vol 1 ◽  
pp. S31-S31
Author(s):  
M MORALES ◽  
D ROVAI ◽  
A GIMELLI ◽  
C MARINI ◽  
U STARTARI ◽  
...  
Keyword(s):  
Myocardial Perfusion ◽  
Nuclear Imaging

Statins and Vulnerable Plaque

2018 ◽  
Vol 23 (46) ◽  
pp. 7069-7085 ◽  
Author(s):  
Maria Drakopoulou ◽  
Konstantinos Toutouzas ◽  
Archontoula Michelongona ◽  
Dimitrios Tousoulis
Keyword(s):  
Statin Therapy ◽  
Vulnerable Plaque ◽  
Vascular Wall ◽  
Statin Treatment ◽  
Duration Of Treatment ◽  
Fibrous Cap ◽  
Plaque Development ◽  
Plaque Stabilization ◽  
Inflammatory Activation ◽  
The One

Background: Atherosclerosis is a systemic, progressive lipid-driven inflammatory disease of the arterial vascular wall leading progressively to plaque development. The vulnerable plaque, the one considered to be the leading cause of cardiovascular events seems to exhibit a large and soft lipid-rich necrotic core covered by a thin and inflamed fibrous cap. Statin treatment is considered as one of the most effective methods for vulnerable plaque stabilization, currently being the principal drug in primary and secondary prevention of cardiovascular disease. </P><P> Objective: We sought to evaluate the beneficial effect of statins on biological processes involved in the evolution of vulnerable plaques </P><P> Method: We performed a systematic review of the literature searching MEDLINE via Pubmed for all experimental and human studies implementing statins in vulnerable plaque. </P><P> Results: Statins seem to have a beneficial role in plaque stabilization and patient outcome. It seems that this effect is mediated by improving endothelial function, decreasing oxidative stress and inflammation, reducing inflammatory activation and inhibiting thrombogenic response. Although these data are quite promising, it remains to be determined the extent of a potent benefit of the pleiotropic effects of statin therapy in clinical setting. </P><P> Conclusion: Prospective randomized trials should be conducted in order to further elucidate differences among type and dose of statin therapy, duration of treatment and association with LDL levels and clinical outcome.

In the Search of the Vulnerable Plaque: Current Diagnostic Techniques and Future Directions

2008 ◽  
Vol 4 (1) ◽  
pp. 21-29
Author(s):  
Manolis Vavuranakis ◽  
Theodore G. Papaioannou ◽  
Christodoulos Stefanadis
Keyword(s):  
Vulnerable Plaque ◽  
Diagnostic Techniques ◽  
Future Directions

Nuclear Imaging

2020 ◽  
pp. 37-45
Author(s):  
William Brawner
Keyword(s):  
Nuclear Imaging
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