Manufacturing Systems and Their Design Principles

Author(s):  
A Galip Hulsoy ◽  
M Mehrabi ◽  
A Galip Ulsoy ◽  
Yoram Koren
Author(s):  
Oliver Moerth-Teo ◽  
◽  
Felix Weger ◽  
Christian Ramsauer

While companies in the entire automotive industry deal with increasing volatility and uncertainty, new trends and innovations pressure especially powertrain margins. The concept of agile manufacturing enables companies to remain competitive in such an environment. As some authors declare that the success of agile manufacturing is largely determined by the design of products, this paper investigates how these two phases in the powertrain lifecycle can be linked. A literature review was conducted to identify DFX guidelines that reflect the agile manufacturing characteristics: flexibility, profitability, speed, proactivity and quality. More than 200 design principles were collected and clustered into seven design objectives according to their main purposes. A first questionnaire was conducted at an engineering company having its main business field in powertrain development in order to define the importance of these principles to enhance agile powertrain manufacturing. The results are presented in a design catalogue. Through an additional literature review the required capabilities of manufacturing systems to fulfill the five agile characteristics were identified. The rating of these capabilities was subject of a second questionnaire at several manufacturing companies in the automotive industry. The employment of a domain mapping matrix supports the selection and application of appropriate product design principles aiming to enhance specific agile manufacturing capabilities. Finally, the developed procedure model was evaluated.


Author(s):  
M. G. Mehrabi ◽  
A. Galip Ulsoy ◽  
Yoram Koren

2020 ◽  
Vol 48 (2) ◽  
pp. 399-409
Author(s):  
Baizhen Gao ◽  
Rushant Sabnis ◽  
Tommaso Costantini ◽  
Robert Jinkerson ◽  
Qing Sun

Microbial communities drive diverse processes that impact nearly everything on this planet, from global biogeochemical cycles to human health. Harnessing the power of these microorganisms could provide solutions to many of the challenges that face society. However, naturally occurring microbial communities are not optimized for anthropogenic use. An emerging area of research is focusing on engineering synthetic microbial communities to carry out predefined functions. Microbial community engineers are applying design principles like top-down and bottom-up approaches to create synthetic microbial communities having a myriad of real-life applications in health care, disease prevention, and environmental remediation. Multiple genetic engineering tools and delivery approaches can be used to ‘knock-in' new gene functions into microbial communities. A systematic study of the microbial interactions, community assembling principles, and engineering tools are necessary for us to understand the microbial community and to better utilize them. Continued analysis and effort are required to further the current and potential applications of synthetic microbial communities.


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