Structural and Functional Roles of C-Type Lectin Receptors on Natural Killer Cells

2008 ◽  
pp. 385-404
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Killer Cells ◽  
Lectin Receptors ◽  
Functional Roles

Synthesis of Linear and Branched Regioisomeric Chitooligosaccharides as Potential Mimetics of Natural Oligosaccharide Ligands of Natural Killer Cells NKR-P1 and CD69 Lectin Receptors

2004 ◽  
Vol 69 (9) ◽  
pp. 1781-1804 ◽  
Author(s):  
Anna Rohlenová ◽  
Miroslav Ledvina ◽  
David Šaman ◽  
Karel Bezouška
Keyword(s):  
Natural Killer Cells ◽  
Nk Cells ◽  
Natural Killer ◽  
Binding Activity ◽  
Structural Requirements ◽  
Killer Cells ◽  
Lectin Receptors ◽  
Lectin Receptor ◽  
Glycosidic Bonds ◽  
Natural Ligands

Regioisomer of chitobiose 13 with β(1→3) glycosidic bond and branched analog of chitotriose 25 having β(1→4) and β(1→3) glycosidic bonds, were prepared and tested as potential mimetics of natural oligosaccharide ligands for activating lectin receptors NKR-P1A and CD69 of natural killer (NK) cells. The structural requirements of NKR-P1 lectin receptor on effective mimetics of its natural ligands has been discussed. A significant binding activity of the branched trisaccharide 25 to the receptor CD69 was observed.

Histological studies of gene-ablated mice support important functional roles for natural killer cells in the uterus during pregnancy

1997 ◽  
Vol 35 (2) ◽  
pp. 111-133 ◽  
Author(s):  
B.Anne Croy ◽  
Ali A. Ashkar ◽  
Robert A. Foster ◽  
James P. DiSanto ◽  
Jeanne Magram ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Killer Cells ◽  
Histological Studies ◽  
Functional Roles

Natural Killer cells exhibit direct activity against medical important fungi

2009 ◽  
Vol 221 (03) ◽  
Author(s):  
S Schmidt ◽  
L Tramsen ◽  
M Hanisch ◽  
S Huenecke ◽  
U Koehl ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Natural Killer ◽  
Killer Cells
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