Rapid Lead Identification of Inhibitors of Adenine Nucleotide Translocase A Case Study of Applying Combinatorial Chemistry Techniques in Drug Discovery

2008 ◽  
pp. 165-176 ◽  
Author(s):  
Yazhong Pei ◽  
Soumitra Ghosh ◽  
Walter Moos
Keyword(s):  
Drug Discovery ◽  
Combinatorial Chemistry ◽  
Adenine Nucleotide ◽  
Adenine Nucleotide Translocase ◽  
Lead Identification

Pure Biologics – From a Bootstrapped Boutique CRO to an Integrated Drug Discovery Public Company

2020 ◽  
Vol 7 (1) ◽  
pp. 48-63
Author(s):  
Sameer Deshmukh ◽  
Przemysław Jurek ◽  
Filip Jelen ◽  
Sabina Tabaczar ◽  
Tomasz Bakowski ◽  
...  
Keyword(s):  
Drug Discovery ◽  
Present Article ◽  
Small And Medium Enterprises ◽  
Public Funding ◽  
Corporate Management ◽  
Publicly Traded ◽  
Biopharmaceutical Company ◽  
Public Company ◽  
Medium Enterprises

The present article is a case study of a Polish biopharmaceutical company, “Pure Biologics”. The company was founded in 2010 by a group of scientists and, over the last nine years, grew substantially from just a few individuals to nearly one hundred professionals. Initially, a privately-funded civil partnership, Pure Biologics, has been transformed into a publicly-traded company. Such a transformation has been possible not only because of the expertise and growing experience of corporate management, but also the specific economic environment and substantial public funding dedicated to innovative Small and Medium Enterprises (SMEs).

scholarly journals Recruitment of NF-κB into Mitochondria Is Involved in Adenine Nucleotide Translocase 1 (ANT1)-induced Apoptosis

2004 ◽  
Vol 279 (37) ◽  
pp. 38415-38423 ◽  
Author(s):  
Monica Zamora ◽  
Claudia Meroño ◽  
Octavi Viñas ◽  
Teresa Mampel
Keyword(s):  
Adenine Nucleotide ◽  
Adenine Nucleotide Translocase ◽  
Induced Apoptosis

scholarly journals An isoform shift in the cardiac adenine nucleotide translocase expression alters the kinetic properties of the carrier in dilated cardiomyopathy

2005 ◽  
Vol 8 (1) ◽  
pp. 81-89 ◽  
Author(s):  
Andrea Dörner ◽  
Stefanie Giessen ◽  
Regina Gaub ◽  
Helga Große Siestrup ◽  
Peter L. Schwimmbeck ◽  
...  
Keyword(s):  
Dilated Cardiomyopathy ◽  
Adenine Nucleotide ◽  
Adenine Nucleotide Translocase ◽  
Kinetic Properties
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