Genetic Polymorphism of N-Acetyltransferase Genes as Risk Modifiers of Colorectal Cancer from Consumption of Well-Done Meat

2006 ◽  
pp. 189-212
Author(s):  
La Creis Renee Kidd ◽  
Robert C.G. Martin ◽  
Jason H. Moore ◽  
David W. Hein
Keyword(s):  
Colorectal Cancer ◽  
Genetic Polymorphism ◽  
Risk Modifiers

Genetic Polymorphism of XRCC1 Correlated with Response to Oxaliplatin-Based Chemotherapy in Advanced Colorectal Cancer

2012 ◽  
Vol 18 (4) ◽  
pp. 1009-1014 ◽  
Author(s):  
Hongying Lv ◽  
Qicai Li ◽  
Wengsheng Qiu ◽  
Jinyu Xiang ◽  
Hongjun Wei ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Genetic Polymorphism ◽  
Advanced Colorectal Cancer

scholarly journals Relationship between growth hormone 1 genetic polymorphism and susceptibility to colorectal cancer

2010 ◽  
Vol 55 (3) ◽  
pp. 163-166 ◽  
Author(s):  
Chang-Ming Gao ◽  
Jian-Ping Gong ◽  
Jian-Zhong Wu ◽  
Hai-Xia Cao ◽  
Jian-Hua Ding ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Growth Hormone ◽  
Genetic Polymorphism

Correlation of genetic polymorphism of TNFα and TGFβ genes with protein level in patients with pancreatic and colorectal cancer in Polish population

2016 ◽  
Vol 61 ◽  
pp. S152
Author(s):  
M. Zagozda ◽  
A. Sarnecka ◽  
Z. Staszczak ◽  
M. Nowak-Niezgoda ◽  
W.L. Olszewski ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Genetic Polymorphism ◽  
Protein Level ◽  
Polish Population

RETRACTED: Genetic Polymorphism of XRCC1 Correlated with Response to Oxaliplatin-based Chemotherapy in Advanced Colorectal Cancer

2013 ◽  
Vol 31 (1) ◽  
pp. 24-28 ◽  
Author(s):  
Hongying Lv ◽  
Qicai Li ◽  
Wengsheng Qiu ◽  
Jinyu Xiang ◽  
Hongjun Wei ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Genetic Polymorphism ◽  
Advanced Colorectal Cancer

scholarly journals COMT val158met Polymorphism and Spinal Analgesia Efficacy of Laparoscopic Surgery for Colorectal Cancer (a Pilot Study)

2019 ◽  
Vol 15 (6) ◽  
pp. 4-10 ◽  
Author(s):  
Alexander L. Potapov ◽  
Daria V. Zemskova ◽  
Tatiana I. Ivanova ◽  
Vera A. Khorokhorina ◽  
Peter V. Shegay ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Laparoscopic Surgery ◽  
Genetic Polymorphism ◽  
Pilot Study ◽  
Healthy Donor ◽  
Spinal Analgesia ◽  
Donor Group ◽  
Comt Val158met ◽  
Val158met Polymorphism ◽  
Hardy Weinberg Equilibrium

The aim: To assess the effect of COMT G1947A genetic polymorphism (val158met) on the efficacy of spinal analgesia on day 1 after laparoscopic surgery for colorectal cancer.Material and methods. In a pilot study involving 100 patients with colorectal cancer, operated through laparoscopic access, using spinal analgesia (10.0–12.5 mg of bupivacaine + 200 mcg of morphine), the frequency of COMT gene G1947A (val158met) polymorphism, the intensity of pain on day 1 after surgery, the frequency and severity of nausea, vomiting, skin itching, the need for additional analgesia have been assessed.Results. The frequency distribution of alleles val/val (25%), val/met (45%) and met/met (30%) was consisted with Hardy-Weinberg equilibrium (χ2=0.96; P>0.05) and was not significantly different from the healthy donor group. In the groups of patients with various COMT alleles of val158met polymorphism, the studied parameters also did not differ significantly.Conclusion. Study did not find significant link between spinal analgesia efficacy on day 1 after laparoscopic surgery for colorectal cancer and COMT rs4680 G1947A (val158met) polymorphism. Further research to enhance the power of the study is warranted to reach the final conclusions.

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