Cognitive Impairment in Transgenic Mouse Models of Amyloid Deposition

2006 ◽  
pp. 183-198 ◽  
Author(s):  
Dave Morgan
Keyword(s):  
Cognitive Impairment ◽  
Transgenic Mouse ◽  
Mouse Models ◽  
Amyloid Deposition ◽  
Transgenic Mouse Models

Transgenic mouse models of Alzheimer's disease: phenotype and mechanisms of pathogenesis

2001 ◽  
Vol 67 ◽  
pp. 195-202 ◽  
Author(s):  
Karen Duff
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Transgenic Mice ◽  
Amyloid Precursor Protein ◽  
Transgenic Mouse ◽  
Mouse Models ◽  
Precursor Protein ◽  
Transgenic Mouse Models ◽  
Disease Phenotype

A range of transgenic mice have been created to model Alzheimer's disease. These include mice expressing human forms of the amyloid precursor protein, the presenilins and, more recently, tau. Several of the models develop features of the disease including amyloid pathology, cholinergic deficits, neurodegeneration and cognitive impairment. Progress in the characterization and use of these model animals is discussed.

Transgenic mouse models of type I diabetes

Diabetes ◽  
1990 ◽  
Vol 39 (8) ◽  
pp. 879-884 ◽  
Author(s):  
M. A. Lipes ◽  
G. S. Eisenbarth
Keyword(s):  
Transgenic Mouse ◽  
Mouse Models ◽  
Type I Diabetes ◽  
Type I ◽  
Transgenic Mouse Models

scholarly journals Characterization of tumor‐associated macrophages in prostate cancer transgenic mouse models

The Prostate ◽  
2021 ◽  
Author(s):  
Amber E. Groot ◽  
Kayla V. Myers ◽  
Timothy E. G. Krueger ◽  
Ashley L. Kiemen ◽  
Natalia H. Nagy ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Transgenic Mouse ◽  
Mouse Models ◽  
Transgenic Mouse Models ◽  
Tumor Associated Macrophages
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