Developmental Behavioral Toxicity of Methylmercury

Animal Models of Cognitive Impairment - Frontiers in Neuroscience ◽

10.1201/9781420004335.ch7 ◽

2006 ◽

pp. 101-146

Author(s):

Wendy Donlin ◽

M Christopher Newland ◽

Kelly Banna ◽

Elliott Paletz

Keyword(s):

Behavioral Toxicity

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Faculty Opinions recommendation of Sex-specific enhanced behavioral toxicity induced by maternal exposure to a mixture of low dose endocrine-disrupting chemicals.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725254111.793504008 ◽

2015 ◽

Author(s):

Martin van den Berg ◽

Milou Dingemans

Keyword(s):

Low Dose ◽

Endocrine Disrupting Chemicals ◽

Maternal Exposure ◽

Behavioral Toxicity ◽

Endocrine Disrupting

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Zebrafish Behavioral Toxicity of Metal-Herbicide Complexes May Explain Similar Effects of Exposure to Water Samples from Sri Lankan Agricultural Regions

SSRN Electronic Journal ◽

10.2139/ssrn.3965234 ◽

2021 ◽

Author(s):

Emily Craig ◽

Remy Babich ◽

Dilini V. Ekanayake ◽

Chuan Yan ◽

Mangala C.S. DeSilva ◽

...

Keyword(s):

Water Samples ◽

Sri Lankan ◽

Behavioral Toxicity ◽

Agricultural Regions

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Behavioral Toxicity Associated with Antiepileptic Drugs: Concepts and Methods of Assessment

Epilepsia ◽

10.1111/j.1528-1157.1986.tb03550.x ◽

1986 ◽

Vol 27 (4) ◽

pp. 331-340 ◽

Cited By ~ 21

Author(s):

R. A. Novelly ◽

M. M. Schwartz ◽

R. H. Mattson ◽

J. A. Cramer

Keyword(s):

Antiepileptic Drugs ◽

Behavioral Toxicity

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Behavioral neurotoxicity in adolescent and adult mice exposed to fenproporex during pregnancy

Human & Experimental Toxicology ◽

10.1191/0960327105ht546oa ◽

2005 ◽

Vol 24 (8) ◽

pp. 403-408 ◽

Cited By ~ 3

Author(s):

C Q Moreira ◽

M JSS Faria ◽

E G Moreira

Keyword(s):

Forced Swimming Test ◽

Tail Suspension Test ◽

Stereotyped Behavior ◽

Dopaminergic Transmission ◽

Adult Mice ◽

Gestational Exposure ◽

Behavioral Toxicity ◽

Anorectic Drugs ◽

Swimming Test ◽

First Time

We investigated the effects of gestational exposure to fenproporex, one of the most used anorectic drugs in Brazil, on the behavior of adolescent and adult pups (30 and 60 days of age, respectively). Pregnant Swiss mice were treated daily, by gavage, with 15 mg/kg of fenproporex chloride or water during the whole gestational period. Male pups were submitted to open-field, forced swimming test, tail suspension test and fenproporexinduced stereotyped behavior. The results demonstrated that gestational exposure to fenproporex induces antidepressant-like effect and decreases fenproporexinduced stereotyped behavior in both adolescent and adult pups. Moreover, fenproporex-exposed adolescent pups tended (P–0.06) to be more active than control pups. Our data show, for the first time, that gestational exposure to fenproporex leads to long-lasting behavioral toxicity in male mice characteristic of altered dopaminergic transmission.

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