Antisense Drug Technology

2020 ◽  
Keyword(s):  
Drug Technology

Nanoemulsions- A better Approach for Anti Diabeticdrugs Delivering

2020 ◽  
Vol 17 ◽  
Author(s):  
V. Manimaran ◽  
Ponnurengam Malliappan Sivakumar ◽  
J. Narayanan ◽  
Shanmugam Parthasarathi ◽  
Pranav Kumar Prabhakar
Keyword(s):  
Aqueous Phase ◽  
Therapeutic Agent ◽  
Antidiabetic Drugs ◽  
Optical Behaviour ◽  
Antimicrobial Drugs ◽  
Drug Degradation ◽  
Oil In Water ◽  
Drug Technology ◽  
Human Use ◽  
Poor Absorption

: Conventional delivery of antidiabetic drugs faces many problems like poor absorption, low bioavailability, and drug degradation. Nanoemulsion is a unique drug technology which is very suitable for the delivery of antidiabetic drugs. In recent years the flaws of delivering anti-hypoglycaemic drugs have been overcome by choosing nanoemulsion drug technology. They are thermodynamically stable and also deliver the therapeutic agent for a longer duration. Generally, Nanoemulsions are made up of either oil-in-water or water-in-oil and size of the droplets is from fifty to thousand nanometer. Surfactants are critical substances which are added in the manufacturing of nanoemulsions. Only the surfactants which are approved for human use can be utilized in the manufacturing of nanoemulsions. Generally, the preparation of emulsions includes mixing of the aqueous phase and organic phase and using surfactant with proper agitation. Nanoemulsions are used for antimicrobial drugs, and they are also used in the prophylaxis of cancer, diabetics. Reduction in the droplet size may cause variation in the elastic and optical behaviour of nanoemulsions.

Antisense Drug Technology

2003 ◽  
Vol 89 (2) ◽  
pp. 355-356
Author(s):  
Francis C. Szoka
Keyword(s):  
Drug Technology

scholarly journals Additive Manufacturing: A 3-Dimensional Approach in Periodontics

2020 ◽  
pp. 105-117
Author(s):  
Anurag Bhatnagar ◽  
Amit Bhardwaj ◽  
Shalu Verma
Keyword(s):  
Additive Manufacturing ◽  
Maxillofacial Surgery ◽  
Oral And Maxillofacial Surgery ◽  
Layer By Layer ◽  
Additive Technology ◽  
3 Dimensional ◽  
Ridge Augmentation ◽  
Drug Technology ◽  
Dimensional Printing

Additive manufacturing technology or 3-dimensional printing has been used since ages in various fields including medical. Their addition to dentistry is recent and has tried to revolutionize the field. It is being used in various fields of dentistry like endodontics, prosthodontics, orthodontics, oral and maxillofacial surgery and recently in periodontics and Implantology. With introduction of recent “layer-by-layer” additive technology, their use in periodontal field has changed its treatment planning. It is use in preparation of customized scaffold with or without stem cell therapy, ridge augmentation, sinus lift and guided implant surgery, implant fixtures, education models, drug technology and many more. This review has tried to explain the various applications of the additive manufacturing in the field of periodontics with recent evidences. This paper highlights the role of 3-dimensional printing which can change the future of periodontal management.   

scholarly journals Forensic and pharmaceutical research on the impact of drugs on the safety, life and health of road users within the organization of pharmaceutical business, drug technology, pharmaceutical and medical law in Ukraine

2021 ◽  
Vol 10 (4) ◽  
pp. 127-132
Author(s):  
V.V. Shapovalov (Jr.) ◽  
V.A. Shapovalova ◽  
V.V. Shapovalov
Keyword(s):  
Traffic Safety ◽  
Traffic Accidents ◽  
Road Traffic ◽  
Pharmaceutical Research ◽  
Psychoactive Drugs ◽  
Medical Law ◽  
Road Traffic Accidents ◽  
Road Users ◽  
Drug Technology ◽  
The Impact

Background. Around the world, drug-related road traffic accidents are one of the leading causes of injury and death among road users. Traffic safety is a system that includes the following components: a person – a person's health condition – the use of dangerous drugs of different classification and legal groups – adverse drug reactions – a vehicle – a road. The share of road traffic accidents under the influence of drugs is more than 75 %, they are also the most socially dangerous, because they have grave consequences, cause irreparable harm to the health and death of the victims. The purpose of the study was to analyze the achievements of forensic and pharmaceutical researches in Ukraine on the impact of drugs on the safety, life and health of road users within the framework of the organization of pharmaceutical business, drug technology, pharmaceutical and medical law in a retrospective aspect. Materials and methods. The materials of the imperative research were legislative, regulatory and legal documents; materials of the formation of the scientific school of forensic pharmacy; scientific publications on the topic of the article; Internet resources, sources of scientific literature. To achieve the set goals, the methods of forensic and pharmaceutical, regulatory, documentary, bibliographic, comparative, historical and graphic analysis were used. Results. The experience of the countries of the world in the prophylaxis and prevention of road traffic accidents under the influence of drugs was analyzed. The causes and conditions for the occurrence and consequences of road traffic accidents are multifactorial in nature and are associated with the victims (driver - pedestrian), vehicle, road conditions, and the use of psychoactive drugs. A system of organizational, regulatory and preventive measures has been developed to provide first medical aid to victims of a road traffic accident. Shown that there is a need for scientifically grounded organizational and legal, clinical and pharmacological, forensic pharmaceutical and socio-economic studies on causal relationships between adverse reactions due to the use of drugs of various classification and legal groups, traffic safety and road traffic accidents. For the first time in Ukraine, a mathematical model was proposed to establish the effect of psychoactive drugs on the driver's condition when driving a vehicle, depending on the calculation of the stopping path of the car in accordance with the selected speed and a decrease in the driver's response. The structure of road traffic accidents under the influence of psychoactive drugs has been investigated. Conclusions. A classification of first-aid kits for providing first medical aid to victims of road traffic accidents was proposed, which made it possible to substantiate the need to improve them both in qualitative and quantitative composition, depending on the type of vehicle and the likelihood of an accident with serious consequences. Recommendations were proposed for providing information on the possibility of obtaining medical care and the signal-calling system on the roads, marking the packages of psychoactive drugs with a special mark in the form of a red triangle. The need for further forensic pharmaceutical research has been proven.

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