C-Glycoside Synthesis

2020 ◽  
Author(s):  
Maarten H.D. Postema
Keyword(s):  
Glycoside Synthesis

A 5‘-(Trifluoromethyl)anthracycline Glycoside:  Synthesis of Antitumor-Active 7-O-(2,6-Dideoxy-6,6,6-trifluoro-α-l-lyxo-hexopyranosyl)adriamycinone

1996 ◽  
Vol 39 (8) ◽  
pp. 1582-1588 ◽  
Author(s):  
Yasushi Takagi ◽  
Ken Nakai ◽  
Tsutomu Tsuchiya ◽  
Tomio Takeuchi
Keyword(s):  
Glycoside Synthesis

Engineering of cellobiose phosphorylase for glycoside synthesis

2011 ◽  
Vol 156 (4) ◽  
pp. 253-260 ◽  
Author(s):  
Manu R.M. de Groeve ◽  
Tom Desmet ◽  
Wim Soetaert
Keyword(s):  
Glycoside Synthesis ◽  
Cellobiose Phosphorylase

ChemInform Abstract: Selectivity in the SmI2-Induced Deoxygenation of Thiazolylketoses for Formyl C-Glycoside Synthesis and Revised Structure of C-Ribofuranosides.

ChemInform ◽  
2010 ◽  
Vol 33 (4) ◽  
pp. no-no
Author(s):  
Alessandro Dondoni ◽  
Paolo Formaglio ◽  
Alberto Marra ◽  
Alessandro Massi
Keyword(s):  
Glycoside Synthesis

ChemInform Abstract: BENZYLATED ORTHOESTERS IN GLYCOSIDE SYNTHESIS, THE SYNTHESIS OF ALPHA-D-GLUCOPYRANOSIDES AND BETA-D-MANNOPYRANOSIDES

1974 ◽  
Vol 5 (10) ◽  
pp. no-no
Author(s):  
HANS B. BOREN ◽  
GOERAN EKBORG ◽  
KARIN EKLIND ◽  
PER J. GAREGG ◽  
AKE PILOTTI ◽  
...  
Keyword(s):  
Glycoside Synthesis

Glycoside Synthesis from Anomeric Halides

2008 ◽  
pp. 29-93 ◽  
Author(s):  
Shin-Ichiro Shoda ◽  
Suvarn S. Kulkarni ◽  
Jacquelyn Gervay-Hague
Keyword(s):  
Glycoside Synthesis

scholarly journals A Novel Dimeric Exoglucanase (GH5_38): Biochemical and Structural Characterisation towards its Application in Alkyl Cellobioside Synthesis

Molecules ◽  
2020 ◽  
Vol 25 (3) ◽  
pp. 746 ◽  
Author(s):  
Mpho S. Mafa ◽  
Heinrich W. Dirr ◽  
Samkelo Malgas ◽  
Rui W. M. Krause ◽  
Konanani Rashamuse ◽  
...  
Keyword(s):  
Glycoside Hydrolase ◽  
Kinetic Studies ◽  
Glycoside Hydrolase Family ◽  
Primary Alcohols ◽  
Structural Characterisation ◽  
Alkyl Glycosides ◽  
Glycoside Synthesis ◽  
One Step ◽  
Ph Range ◽  
The One

An exoglucanase (Exg-D) from the glycoside hydrolase family 5 subfamily 38 (GH5_38) was heterologously expressed and structurally and biochemically characterised at a molecular level for its application in alkyl glycoside synthesis. The purified Exg-D existed in both dimeric and monomeric forms in solution, which showed highest activity on mixed-linked β-glucan (88.0 and 86.7 U/mg protein, respectively) and lichenin (24.5 and 23.7 U/mg protein, respectively). They displayed a broad optimum pH range from 5.5 to 7 and a temperature optimum from 40 to 60 °C. Kinetic studies demonstrated that Exg-D had a higher affinity towards β-glucan, with a Km of 7.9 mg/mL and a kcat of 117.2 s−1, compared to lichenin which had a Km of 21.5 mg/mL and a kcat of 70.0 s−1. The circular dichroism profile of Exg-D showed that its secondary structure consisted of 11% α-helices, 36% β-strands and 53% coils. Exg-D performed transglycosylation using p-nitrophenyl cellobioside as a glycosyl donor and several primary alcohols as acceptors to produce methyl-, ethyl- and propyl-cellobiosides. These products were identified and quantified via thin-layer chromatography (TLC) and liquid chromatography–mass spectrometry (LC-MS). We concluded that Exg-D is a novel and promising oligomeric glycoside hydrolase for the one-step synthesis of alkyl glycosides with more than one monosaccharide unit.

Sc(OTf)3 as Efficient Catalyst for Aryl C-Glycoside Synthesis.

ChemInform ◽  
2004 ◽  
Vol 35 (23) ◽  
Author(s):  
Akimi Ben ◽  
Takahito Yamauchi ◽  
Takashi Matsumoto ◽  
Keisuke Suzuki
Keyword(s):  
Efficient Catalyst ◽  
Glycoside Synthesis
Sign in / Sign up

Export Citation Format

Share Document