scholarly journals Trends in Melanoma Mortality in Brazil: A Registry-Based Study

2020 ◽  
pp. 1766-1771
Author(s):  
Guilherme Nader Marta ◽  
Rodrigo Ramella Munhoz ◽  
Monica La Porte Teixeira ◽  
Bernadette Cunha Waldvogel ◽  
Veridiana Pires de Camargo ◽  
...  
Keyword(s):  
Mortality Rates ◽  
Demographic Variables ◽  
Southeastern Brazil ◽  
Mortality Data ◽  
Demographic Information ◽  
Mortality Trend ◽  
Mortality Trends ◽  
Cross Sectional ◽  
The Past ◽  
Melanoma Mortality

PURPOSE A substantial increase in melanoma incidence has been consistently observed worldwide over the past decades. However, melanoma mortality rates have remained stable or declined over the past years in most regions. Given the paucity of melanoma mortality data for different Brazilian regions, we sought to describe melanoma mortality trends in southeastern Brazil and their relationship with demographic variables. MATERIALS AND METHODS A cross-sectional registry-based analysis was conducted to describe melanoma mortality trends in the state of São Paulo, Brazil, from 1996 to 2016. Demographic information from melanoma-related death records, including sex and age, was collected from the Fundação Sistema Estadual de Análise de Dados database. The annual percentage change (APC) was calculated to identify mortality trends over the period. RESULTS An increasing melanoma mortality trend was detected among males, regardless of age (APC, 1.72%; P < .001), and was more pronounced for men ≥ 60 years old (APC, 2.63%; P < .001). Melanoma mortality rates have also increased for patients ≥ 60 years old, regardless of sex (APC, 1.11%; P < .001). A non–statistically significant increase in the overall melanoma mortality rate was observed over the 20-year period analyzed (APC, 0.36%; P = .4). CONCLUSION Our data suggest a stable melanoma mortality over the past two decades for the overall population studied; however, a significant increase in melanoma mortality rates has been demonstrated among males and in the population ≥ 60 years old, emphasizing the need to implement prevention strategies and expand access to effective therapies for this population.

scholarly journals Cancer Mortality Trend in Central Italy: Focus on A “Low Rate of Land Use” Area from 1982 to 2011

2019 ◽  
Vol 16 (4) ◽  
pp. 628 ◽  
Author(s):  
Francesca Santilli ◽  
Stefano Martellucci ◽  
Jennifer Di Pasquale ◽  
Cecilia Mei ◽  
Fabrizio Liberati ◽  
...  
Keyword(s):  
Land Use ◽  
Cancer Mortality ◽  
Central Italy ◽  
Mortality Rates ◽  
Mortality Data ◽  
Mortality Trends ◽  
High Prevalence ◽  
Oncological Diseases ◽  
Total Cancer ◽  
Low Rate

The aim of the present study was to estimate total cancer mortality trends from 1982 to 2011 in a “low rate of land use” province of the Latium region (Rieti, central Italy) characterized by a low degree of urbanization, a high prevalence of elderly, and a low number of births. Mortality data of the studied period, provided by the Italian National Institute of Statistics, were used for calculating standardized cancer mortality rates. Trends in mortality were analyzed using Joinpoint regression analysis. Results showed that total standardized cancer mortality rates decreased in the monitored area over the study period. A comparison with other provinces of the same region evidenced that the studied province presented the lowest cancer mortality. The three systems/apparatuses affected by cancer that mainly influenced cancer mortality in the monitored province were the trachea-bronchus-lung, colorectal-anus, and stomach. These findings could be attributed to the implement of preventive initiatives performed in the early 2000s, to healthier environmental scenario, and to lower levels of carcinogenic pollutants in air, water, and soil matrices. Thus, our results indicate that the studied area could be considered a “healthy” benchmark for studies in oncological diseases.

scholarly journals Nutritional status of 11–12-year-old Jamaican children: coexistence of under- and overnutrition in early adolescence

2002 ◽  
Vol 5 (2) ◽  
pp. 281-288 ◽  
Author(s):  
Maria Jackson ◽  
Maureen Samms-Vaughan ◽  
Deanna Ashley
Keyword(s):  
Nutritional Status ◽  
Early Adolescence ◽  
Demographic Variables ◽  
Demographic Information ◽  
Cross Sectional ◽  
Factors Associated ◽  
Public Health Significance ◽  
Rehabilitative Intervention ◽  
The Usa ◽  
Health Significance

AbstractObjective:To determine the nutritional status of a cohort of 11–12 year olds and ascertain social and demographic factors associated with under- and overweight in early adolescence.Design:Cross-sectional.Subjects:Subgroup (n=1698) of the birth cohort (September–October 1986) of the Jamaican Perinatal Survey enrolled in schools in the Kingston Metropolitan area. One thousand and sixty-three parents or caregivers provided social and demographic information.Results:Undernutrition and overnutrition are of public health significance among adolescent Jamaican children. Ten per cent of 11–12 year olds had body mass index (BMI) values below the 5th percentile (boys, 10.6%; girls, 7.1%) but this prevalence is relatively low compared with other developing countries. The prevalence of stunting was low (3%). The prevalence of overweight (BMI≥85th percentile) (19.3%) was approaching prevalence rates found in the USA. Similar social and demographic variables were associated with thinness and fatness in males. Birth weight predicted overweight in girls.Conclusions:Under- and overnutrition in early adolescence are important problems in Jamaica. There is a need to address both under- and overnutrition in adolescence in preventive and rehabilitative intervention programmes.

scholarly journals Patterns of breast, prostate and cervical cancer incidence and mortality in Colombia: An administrative registry data analysis

2020 ◽  
Author(s):  
Juliana Alexandra Hernández Vargas ◽  
Paula Ximena Ramírez Barbosa ◽  
Ana Milena Gil Quijano ◽  
Ana María Valbuena García ◽  
Lizbeth Acuña Merchán ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Incidence ◽  
Public Health Problem ◽  
Mortality Rates ◽  
Eastern Region ◽  
Global Public Health ◽  
Cervical Cancer Incidence ◽  
Mortality Trends ◽  
Cross Sectional ◽  
Incidence And Mortality

Abstract Background Cancer is widely recognized as a global public health problem. Breast, prostate and cervical cancer are among the most frequent types in developing countries. Assessing their incidence and mortality by regions and municipalities is important to guide evidence-based health policy. Our aim was to describe the incidence and mortality trends for breast, cervical and prostate cancer across regions and municipalities in Colombia during 2018. Methods We performed a cross-sectional analysis with data from people with breast, prostate or cervical cancer, reported to the National Administrative Cancer Registry during 2018. A descriptive analysis was performed. Age-standardized incidence and mortality rates were estimated at national, regional and municipal levels. Finally, we identify the regions and municipalities with significantly higher or lower incidence and mortality rates compared to national estimations. Results Breast cancer was the most frequent type among all new cases and deaths in Colombia. Breast, prostate and cervical cancer incidence and mortality rates were: 18,69 (CI 95%: 18,15–19,25) and 10,48 (CI 95%: 10,07–10,91); 11,34 (CI 95%: 10,90 − 11,78) and 7,58 (CI 95%: 7,22 − 7,96); 5,93 (CI 95%: 5,62 − 6,25) and 4,31 (CI 95%: 4,05 − 4,58), respectively. Eastern region had both, incidence and mortality rates, significantly lower than national for all types of cancer. By municipalities, there were a heterogeneous pattern. Nonetheless, Agua de Dios (Cundinamarca), had one of the highest incidence rates for all types. Conclusions We observed clear differences in cancer incidence and mortality across regions and municipalities, depending on each type of cancer. Our findings are important to improve screening coverage, early detection and treatment in the country.

scholarly journals Patterns of breast, prostate and cervical cancer incidence and mortality in Colombia: An administrative registry data analysis

2020 ◽  
Author(s):  
Juliana Alexandra Hernández Vargas ◽  
Paula Ximena Ramírez Barbosa ◽  
Ana Milena Gil Quijano ◽  
Ana María Valbuena García ◽  
Lizbeth Acuña Merchán ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Incidence ◽  
Public Health Problem ◽  
Mortality Rates ◽  
Eastern Region ◽  
Global Public Health ◽  
Cervical Cancer Incidence ◽  
Mortality Trends ◽  
Cross Sectional ◽  
Incidence And Mortality

Abstract Background: Cancer is widely recognized as a global public health problem. Breast, prostate, and cervical cancer are among the most frequent types in developing countries. Assessing their incidence and mortality by regions and municipalities is important to guide evidence-based health policy. Our aim was to describe the incidence and mortality trends for breast, cervical, and prostate cancer across regions and municipalities in Colombia during 2018.Methods: We performed a cross-sectional analysis with data from people with breast, prostate, or cervical cancer, reported to the National Administrative Cancer Registry during 2018. A descriptive analysis was performed. Age-standardized incidence and mortality rates were estimated at national, regional, and municipal levels. Finally, we identify the regions and municipalities with significantly higher or lower incidence and mortality rates compared to national estimations. Results: Breast cancer was the most frequent type among all new cases and deaths in Colombia. Breast, prostate and cervical cancer incidence and mortality rates per 100,000 were: 18.69 (CI 95%: 18.15-19.25) and 10.48 (CI 95%: 10.07-10.91); 11.34 (CI 95%: 10.90-11.78) and 7.58 (CI 95%: 7.22-7.96); 5.93 (CI 95%: 5.62-6.25) and 4.31 (CI 95%: 4.05-4.58), respectively. Eastern region had both, incidence and mortality rates, significantly lower than national for all types of cancer. By municipalities, there was a heterogeneous pattern. Nonetheless, Agua de Dios (Cundinamarca), had one of the highest incidence rates for all types. Conclusions: We observed clear differences in cancer incidence and mortality across regions and municipalities, depending on each type of cancer. Our findings are important to improve screening coverage, early detection, and treatment in the country.

scholarly journals Recent adverse mortality trends in Scotland: comparison with other high-income countries

2019 ◽  
Author(s):  
Lynda Fenton ◽  
Jon Minton ◽  
Julie Ramsay ◽  
Maria Kaye-Bardgett ◽  
Colin Fischbacher ◽  
...  
Keyword(s):  
Northern Ireland ◽  
Life Expectancy ◽  
Mortality Rates ◽  
Recent Change ◽  
High Income ◽  
Mortality Data ◽  
List Type ◽  
Segmented Regression ◽  
Mortality Trends ◽  
The Usa

AbstractObjectiveGains in life expectancy have faltered in several high-income countries in recent years. We aim to compare life expectancy trends in Scotland to those seen internationally, and to assess the timing of any recent changes in mortality trends for Scotland.SettingAustria, Croatia, Czech Republic, Denmark, England & Wales, Estonia, France, Germany, Hungary, Iceland, Israel, Japan, Korea, Latvia, Lithuania, Netherlands, Northern Ireland, Poland, Scotland, Slovakia, Spain, Sweden, Switzerland, USA.MethodsWe used life expectancy data from the Human Mortality Database (HMD) to calculate the mean annual life expectancy change for 24 high-income countries over five-year periods from 1992 to 2016, and the change for Scotland for five-year periods from 1857 to 2016. One- and two-break segmented regression models were applied to mortality data from National Records of Scotland (NRS) to identify turning points in age-standardised mortality trends between 1990 and 2018.ResultsIn 2012-2016 life expectancies in Scotland increased by 2.5 weeks/year for females and 4.5 weeks/year for males, the smallest gains of any period since the early 1970s. The improvements in life expectancy in 2012-2016 were smallest among females (<2.0 weeks/year) in Northern Ireland, Iceland, England & Wales and the USA and among males (<5.0 weeks/year) in Iceland, USA, England & Wales and Scotland. Japan, Korea, and countries of Eastern Europe have seen substantial gains in the same period. The best estimate of when mortality rates changed to a slower rate of improvement in Scotland was the year to 2012 Q4 for males and the year to 2014 Q2 for females.ConclusionLife expectancy improvement has stalled across many, but not all, high income countries. The recent change in the mortality trend in Scotland occurred within the period 2012-2014. Further research is required to understand these trends, but governments must also take timely action on plausible contributors.Strengths and limitations of this studyThe use of five-year time periods for comparison of life expectancy changes reduces the influence of year-to-year variation on observations.Examining long-term trends addresses concerns that recent life expectancy stalling may be over-emphasised due to notably large gains in the immediately preceding period.The international comparison was limited to the 24 high-income countries for which data were readily available for the relevant period.Analysis of trend data will always be sensitive to the period selected, however segmented regression of the full period of mortality rates available offers an objective method of identifying the timing of a change in trend.

scholarly journals Leukemia mortality in children from Latin America: Trends and predictions to 2030

2020 ◽  
Author(s):  
J. Smith Torres-Roman ◽  
Bryan Valcarcel ◽  
Pedro Guerra-Canchari ◽  
Camila Alves Dos Santos ◽  
Isabelle Ribeiro Barbosa ◽  
...  
Keyword(s):  
Latin American ◽  
Mortality Rates ◽  
World Health ◽  
Mortality Data ◽  
Mortality Trends ◽  
Annual Percent Change ◽  
Universal Healthcare ◽  
The World ◽  
Health Organization ◽  
Universal Healthcare Coverage

Abstract Background: Reports suggest that Latin American and Caribbean (LAC) countries have not reduced in leukemia mortality compared to high-income countries. However, updated trends remain largely unknown in the region. Given that leukemia is the leading cause of cancer-related death in LAC children, we evaluated mortality trends in children (0-14y) from 15 LAC countries for the period 2000-2017 and predicted mortality to 2030.Methods: We retrieved cancer mortality data using the World Health Organization Mortality Database. Mortality rates (standardized to the world standard SEGI population) were analyzed for 15 LAC countries. We evaluated the average mortality rates for the last 5 years (2013-2017). Joinpoint regression analysis was used to evaluate leukemia mortality trends and provide an estimated annual percent change (EAPC). Nordpred was utilized for the calculation of predictions until 2030.Results: Between 2013 and 2017, the highest mortality rates were reported in Venezuela, Ecuador, Nicaragua, Mexico, and Peru. Upward mortality trends were reported in Nicaragua (EAPC by 2.9% in boys, and EAPC by 2.0% in girls), and Peru (EAPC by 1.4% in both sexes). Puerto Rico experienced large declines in mortality among both boys (EAPC by −9.7%), and girls (EAPC by −6.0%). Leukemia mortality will increase in Argentina, Ecuador, Guatemala, Panama, Peru, and Uruguay by 2030.Conclusion: Leukemia mortality is predicted to increase in some LAC countries by 2030. Interventions to prevent this outcome should be tailor to reduce the socioeconomic inequalities and ensure universal healthcare coverage.

The aetiology, epidemiology, clinical features, and investigation of kidney cancer

2017 ◽  
Author(s):  
Nilay Patel ◽  
David Cranston ◽  
Mark Sullivan
Keyword(s):  
Renal Cancer ◽  
Mortality Rates ◽  
Small Renal Masses ◽  
Renal Masses ◽  
Cross Sectional ◽  
The Past ◽  
Urological Malignancies ◽  
Number Of Patients ◽  
Cross Sectional Imaging ◽  
Sectional Imaging

Over 270,000 patients worldwide are diagnosed with renal cancer every year. It is the most lethal of all urological malignancies, with 33–44% of patients dying as a result of the disease. The past three decades has seen the incidence of renal cancer increasing by approximately 2% per year. This increased incidence has predominantly been within localized tumours, detected incidentally due to the increased use of cross-sectional imaging in medical practice. Despite an increase in the number of patients undergoing surgery for renal cancer, mortality rates have continued to rise. There is some evidence to suggest this may be a consequence of the overdiagnosis and overtreatment of small renal masses. At present, there is no justification for national screening programmes for renal cancer.

Accelerated melanoma mortality rates among middle-aged white males with tumors of all thicknesses.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e21029-e21029
Author(s):  
Juliana Berk-Krauss ◽  
David Polsky ◽  
Jennifer Stein ◽  
Alan Geller
Keyword(s):  
White Women ◽  
Age Groups ◽  
White Men ◽  
Mortality Rates ◽  
Age Group ◽  
Middle Aged ◽  
Mortality Trends ◽  
Men And Women ◽  
And Gender ◽  
Melanoma Mortality

e21029 Background: Effective early detection of melanoma remains one of the most crucial strategies in improving patient prognosis, due to the inverse relationship between primary tumor thickness and survival time. However, recent studies have demonstrated the mortality burden of thin melanomas is at least as severe as that of thicker melanomas. Recognizing specific mortality trends among men and women by age and thickness is essential for establishing targeted melanoma screening efforts. Methods: We evaluated Surveillance, Epidemiology and End Results (SEER) data from 2009-2013. Melanoma thickness was divided into four standard categories: 0.01-1.00mm, 1.01-2.00mm, 2.01-4.00mm and > 4.01 mm. Melanoma mortalities were calculated among white men and women by age and thickness. We used a Bayesian analysis to calculate the probability of an individual dying from a melanoma of a given gender, age, and thickness. We then compared these probabilities between men and women. Results: Among white men, the largest increases in mortality rates occurred in the jump from the 45-49 to 50-54 age group at an increase of 68% for 0.01-1.00mm tumors, and from the 50-54 to 55-59 age group at an increase of 91% for 1.01-2.00mm tumors, 71% 2.01-4.00mm tumors and 80% for > 4.01mm tumors. In white women, mortality rates regardless of thickness increased at a slow incremental pace, across all age groups at an average overall rate of 36%. Mortality rates for white men with < 1mm and 1.01-2mm melanomas were comparable within the age groups less than 64 years, as was the case for white women with tumors of these thicknesses. The probability of a man dying was greater than of a woman for any age or thickness category. Conclusions: Melanoma mortality rate trends are nuanced and can vary significantly by age, thickness, and gender. In white men, mortality rates begin to accelerate sharply around the mid-50s age group. Screening efforts should therefore target detecting melanoma in middle-aged males in the in situ or earliest stage.

Abstract 13360: The Association Between Food Insecurity and Cardiovascular Mortality in the United States From 2011 to 2017 - A Longitudinal Analysis

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Stephen Y Wang ◽  
Atheendar S Venkataramani ◽  
Christina A Roberto ◽  
Lauren A Eberly ◽  
Peter W Groeneveld ◽  
...  
Keyword(s):  
Food Insecurity ◽  
Fixed Effects ◽  
The United States ◽  
Mortality Rates ◽  
County Level ◽  
Elderly Adults ◽  
Mortality Trends ◽  
Annual Percent Change ◽  
Cross Sectional ◽  
Longitudinal Changes

Introduction: Prior analyses suggest a link between food insecurity and cardiovascular (CV) health but are limited by cross-sectional designs. We investigated whether longitudinal changes in food insecurity are independently associated with CV mortality. Methods: Using National Center for Health Statistics data, we determined annual U.S. county-level age-adjusted CV mortality rates for non-elderly (20-64 years old) and elderly (65 years and older) adults. County-level food insecurity rates were obtained from the Map the Meal Gap project. We examined CV mortality trends by quartiles of average annual percent change (APC) in food insecurity. Using a Poisson fixed effects estimator, we assessed the association between longitudinal changes in food insecurity and CV mortality rates after accounting for time-varying demographic (proportion of residents who were male, black, Hispanic), economic (median household income, unemployment, poverty, education attainment, and housing vacancy rates), and healthcare access (insurance coverage, density of healthcare providers and hospital beds) variables. Results: Between 2011 and 2017, mean food insecurity rates decreased from 14.7% to 13.3%. In counties in the highest quartile of APC for absolute value change in food insecurity, non-elderly CV mortality increased from 82.2(SD=33.9) to 87.4(SD=37.3) per 100,000 individuals (p<0.001), while in counties in the lowest quartile of APC, mortality was stable [60.8(SD=22.2) to 60.0(SD=23.0) per 100,000 individuals, p=0.64]. Elderly CV mortality significantly declined in all quartiles [1643.3(SD=315.7) to 1542.7(SD=299.4) per 100,000 (p<0.001) in the highest quartile and 1408.3(SD=225.9) to 1338.6(SD=213.8) per 100,000 (p<0.001) in the lowest quartile). A 1 percentage point increase in food insecurity was independently associated with a 0.83% (95% CI 0.42 - 1.25, P<0.001) increase in CV mortality for non-elderly adults. This was not significant for elderly adults (-0.06%, 95% CI -0.39 - 0.28, P=0.74). Conclusion: From 2011 to 2017, an increase in food insecurity was independently associated with an increase in CV mortality rates for non-elderly adults in the U.S. Interventions targeting food insecurity may play a role in improving community CV health.

scholarly journals Trends in cerebrovascular diseases mortality in Serbia, 1997–2016: a nationwide descriptive study

BMJ Open ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. e024417 ◽  
Author(s):  
Irena Ilic ◽  
Milena Ilic ◽  
Sandra Sipetic Grujicic
Keyword(s):  
Treatment Guidelines ◽  
Cohort Analysis ◽  
Descriptive Study ◽  
Mortality Rates ◽  
Cerebrovascular Diseases ◽  
Joinpoint Regression ◽  
Mortality Trend ◽  
Mortality Trends ◽  
Joinpoint Regression Analysis ◽  
Period Effects

ObjectivesOver the last decades, mortality from cerebrovascular diseases (CVDs) has decreased in many countries. The aim of this study was to assess the trends of CVDs mortality in Serbia.MethodsDescriptive epidemiological study. Age-standardised rates (ASRs) for CVDs mortality were assessed by joinpoint regression analysis to identify significant changes in trends and estimate annual per cent changes with 95% CI. The age-period-cohort analysis has been used to describe variations in mortality.ResultsOver this 20-year period, there were 312 847 deaths from CVDs, with the overall average annual ASR of 148.4 per 100 000. The trend of ASRs from CVDs mortality in males in Serbia showed a significant joinpoint: rates insignificantly decreased from 1997 to 2005 by −0.8% per year (95% CI −1.7% to 0.2%) and thereafter rapidly decreased by −5.0% per year (95% CI −5.6% to −4.5%). A joinpoint for females was found in 2006: the mortality trend was first significantly decreasing by −1.0% per year (95% CI −1.9% to −0.0%) and then sharply falling down by −6.0% per year (95% CI −6.8% to −5.3%). Results of age-period-cohort analysis indicated that the relative risk for CVDs mortality showed statistically significant (p<0.05) cohort and period effects, as well as the net drift and local drifts in Serbian population. The trends in mortality for all subtypes of CVDs were similar in both sexes: trends significantly decreased for most subtypes, with the exception of a significant increase for cerebral infarction.ConclusionsAfter a decade of increase, CVDs mortality rates are declining in last decade in Serbia. However, mortality rates from CVDs remain exceedingly high in Serbia. Differences in mortality trends of the stroke subtypes should be taken into account in the creation of both prevention and treatment guidelines.

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