scholarly journals Assessment and Management of Cognitive Symptoms in Patients With Brain Tumors

2021 ◽  
pp. e90-e99
Author(s):  
Michael W. Parsons ◽  
Jörg Dietrich
Keyword(s):  
Quality Of Life ◽  
Brain Tumors ◽  
Neurocognitive Function ◽  
Life Assessment ◽  
Screening Tools ◽  
Cognitive Symptoms ◽  
Disease Course ◽  
Prophylactic Measures ◽  
Subjective Cognitive Function

Cognitive symptoms occur in almost all patients with brain tumors at varying points in the disease course. Deficits in neurocognitive function may be caused by the tumor itself, treatment (surgery, radiation, or chemotherapy), or other complicating factors (e.g., seizures, fatigue, mood disturbance) and can have a profound effect on functional independence and quality of life. Assessment of neurocognitive function is an important part of comprehensive care of patients with brain tumors. In the neuro-oncology clinic, assessment may include cognitive screening tools and inquiry into subjective cognitive function. Neuropsychological assessment is an important adjunct to identify cognitive symptoms and can be used as an opportunity to intervene through transformative feedback and treatment planning. Preventative measures can be taken to reduce cognitive side effects of treatment, such as awake craniotomies with intraoperative mapping during neurosurgery or prophylactic measures during radiation therapy (e.g., hippocampal avoidance, neuroprotectant treatment with memantine). Rehabilitative therapies, including cognitive rehabilitation and computerized cognitive exercise, are options for managing cognitive problems in an individualized manner. Pharmacotherapy, including use of stimulant medications and acetylcholinesterase inhibitors, has shown benefits for patients with brain tumors when tailored to an individual’s cognitive profile. Identification and management of co-occurring issues, such as sleep disturbance, fatigue, and depression, can also improve neurocognitive function. There are promising therapies under development that may provide new options for treatment in the future. Integrating careful assessment and treatment of cognition throughout the disease course for patients with brain tumors can improve functional outcomes and quality of life.

scholarly journals OS05.3 Digital Phenotyping: A Novel Method for Quality of Life Assessment in Patients with Brain Tumors

2017 ◽  
Vol 19 (suppl_3) ◽  
pp. iii9-iii9 ◽  
Author(s):  
D. J. Cote ◽  
I. Barnett ◽  
J. T. Senders ◽  
H. Y. Dawood ◽  
P. Staples ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Brain Tumors ◽  
Life Assessment ◽  
Quality Of Life Assessment ◽  
Digital Phenotyping ◽  
Novel Method

scholarly journals QLIF-18. DIGITAL PHENOTYPING: A NOVEL METHOD FOR QUALITY OF LIFE ASSESSMENT IN PATIENTS WITH BRAIN TUMORS

2017 ◽  
Vol 19 (suppl_6) ◽  
pp. vi205-vi205
Author(s):  
David Cote ◽  
Ian Barnett ◽  
Joeky Senders ◽  
Hassan Dawood ◽  
Patrick Staples ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Brain Tumors ◽  
Life Assessment ◽  
Quality Of Life Assessment ◽  
Digital Phenotyping ◽  
Novel Method

scholarly journals Cognition and quality of life relationship among the elderly community: a cross-sectional study

2020 ◽  
Vol 73 (suppl 3) ◽  
Author(s):  
Barbara Maria Lopes da Silva Brandão ◽  
Alice Maria Barbosa da Silva ◽  
Rafaella Queiroga Souto ◽  
Fabia Alexandra Pottes Alves ◽  
Gleicy Karine Nascimento de Araújo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Family Health ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Life Assessment ◽  
Screening Tools ◽  
Sectional Study ◽  
Cross Sectional ◽  
Quantitative Descriptive

ABSTRACT Objective: to assess cognitive functions and their association with quality of life among elderly people enrolled in a Family Health Unit (FHU) of Primary Health Care in Recife-PE. Methods: a quantitative, descriptive, cross-sectional study in which elderly aged 60 years and over were studied. Results: 76.7% of the elderly were women and the age group was less than or equal to 70 years. 68.6% had cognitive impairment, and in the quality of life assessment it was found that the social participation facet had the highest mean score among the elderly (14.25), while the lowest was observed in the sensory functioning facet (9.10). There was an association between cognitive decline and quality of life. Conclusion: most of the elderly had good quality of life rates, but low cognitive level. Using screening tools allows early detection of health problems, guiding the nursing staff in the construction of preventive measures.

scholarly journals Untreated depressive symptoms significantly worsen quality of life in old age and may lead to the misdiagnosis of dementia: a cross-sectional study

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Viktor Voros ◽  
Sandor Fekete ◽  
Tamas Tenyi ◽  
Zoltan Rihmer ◽  
Ilona Szili ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cognitive Impairment ◽  
Depressive Symptoms ◽  
Older People ◽  
Old Age ◽  
Older Persons ◽  
Screening Tools ◽  
Cognitive Symptoms

Abstract Background Several studies demonstrated the role of depressive mood and cognitive impairment in the background of elevated mortality and decreased Quality of Life (QoL) in old age. Our aim was to assess depressive and cognitive symptoms among older people in order to determine if those are recognized and treated or not, to elucidate the association between them and to investigate their impact on QoL. Methods In the framework of the ICT4Life project self-administered questionnaires and clinical screening tools were used to assess QoL, depressive symptoms and cognitive functions of 60 older persons over the age of 65. Results Males found to be depressed (53.8 vs. 40.4%) and cognitively declined (53.8 vs. 48.9%) more frequently; and had higher scores on the depression (6.85 vs. 5.32) and lower on the QoL (47.38 vs. 50.19) scales. Depressed older persons had lower cognitive levels (24.39 vs. 21.52) and their QoL was significantly poorer (53.97 vs. 43.85) than that of the non-depressed subjects. Depressive symptoms were detected in almost half of the older adults (43.9%), and the majority (80.77%) did not receive antidepressant medication. Conclusions Depressive and cognitive symptoms found to be common among older people, but were not recognized and treated in most cases. Close correlation between depression and cognitive impairment was also confirmed, as well as the key role of depression in the background of pseudo-dementia and QoL decline. Early recognition of depressive symptoms is important not only to treat the underlying mood disorder, but also to improve QoL of older persons.

Methods for quality of life assessment in children with orphanic diseases

2020 ◽  
Vol 28 (Special Issue) ◽  
Author(s):  
Makarova E. V. ◽  
◽  
Krysanov I. S. ◽  
Vasilyeva T. P. ◽  
Alexandrova O. Yu. ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Life Assessment ◽  
Quality Of Life Assessment

Assessment of quality of life of patients with Cushing's syndrome depending on the disease course

2017 ◽  
Author(s):  
Gulchekhra Narimova ◽  
Zamira Yusupovna ◽  
Ravshan Fayzullaev ◽  
Iskandar Arifjanov
Keyword(s):  
Quality Of Life ◽  
Cushing’S Syndrome ◽  
Cushing's Syndrome ◽  
Disease Course

Histamine metabolism disorder in pathogenesis of chronic pelvic pain in patients with external genital endometriosis

2017 ◽  
pp. 56-60
Author(s):  
М.Р. Оразов ◽  
В.Е. Радзинский ◽  
М.Б. Хамошина ◽  
Е.Н. Носенко ◽  
Э.С. Токаева ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Pelvic Pain ◽  
Peripheral Blood ◽  
Chronic Pelvic Pain ◽  
Pain Syndrome ◽  
Histamine Level ◽  
Life Assessment ◽  
Assay Method ◽  
Histamine Metabolism

Цель исследования - изучение особенностей обмена гистамина при хронической тазовой боли у пациенток с наружным генитальным эндометриозом. Методика. В сыворотке крови 100 пациенток методом высокоточного (в нг/мл) иммуноферментного твердофазного анализа определяли концентрацию гистамина. Использованы реактивы «Histamine ЕLISA», аппарат BAE-1000 Гистамин (Labor Diagnostika Nord - LDN, Германия). Оценка выраженности болевого синдрома осуществлялась по шкале ВАШ, оценка качества жизни - на основании опросника для оценки качества жизни при эндометриозе (EHR-30), оценка тревожности - опросника Спилбергера-Ханина. Результаты. Показано статистически значимое повышение уровня гистамина у пациенток с высокой интенсивностью болевого синдрома. Женщины с наружным генитальным эндометриозом, сопровождающимся интенсивным болевым синдромом в 100% случаев обнаруживали высокие уровни ситуативной и личностной тревожности, тогда как, лишь у 40% женщин (n = 16) контрольной группы выявлен умеренный уровень тревожности. Депрессивные расстройства выявлены у 58,3% женщин с хронической тазовой болью (n = 35), из них основную часть (n = 20) составили женщины с выраженной степенью болевого синдрома по ВАШ. Заключение. Психоэмоциональное состояние женщин с тазовой болью, ассоциированной с наружным генитальным эндометриозом, характеризуется высокими уровнями депрессивных и тревожных расстройств, значительным снижением уровня качества жизни. Выявлена прямая связь между интенсивностью болевого синдрома и уровнем гистамина в периферической крови пациенток с наружным генитальным эндометриозом. Objective. To study features of histamine metabolism in patients with chronic pelvic pain associated with external genital endometriosis. Methods. For quantitative assessment of histamine level in peripheral blood was taken from 100 patients which than was centrifuged. In blood serum histamine concentration was determined by enzyme-linked immunosorbent assay method with reagents «Histamine ЕLISA» on the machine BAE-1000 Histamine (Labor Diagnostika Nord - LDN, Hermany). A pain syndrome was assessed by Visual Analog Scale (VAS), quality of life assessment - by Endometriosis Health Profile Questionnaire (EHR-30), level of anxiety was determined by Spielberger-Khanin questionnaire. The results. Showed statistically higher histamine level in patients with severe pain according to VAS. After assessment of results obtained from Spielberger-Khanin questionnaire 100% experimental group’s women with external genital endometriosis (n = 60) were noted to be have high level of state and trait anxiety, then 40% women of control group (n = 16) have moderate level of anxiety. The incidence of depression in women with chronic pelvic pain was 58.3% (n = 35) and the main part (n = 20) were women with severe stage of pelvic pain according to VAS. Conclusions. Psycho emotional condition of women with external genital endometriosis associated pelvic pain characterized by higher depression and anxiety levels, with significant decrease quality of life. Direct relationship also was found between pain syndrome intensity and histamine level in peripheral blood in patients with external genital endometriosis.

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