scholarly journals Predicting Emergency Visits and Hospital Admissions During Radiation and Chemoradiation: An Internally Validated Pretreatment Machine Learning Algorithm

2018 ◽  
pp. 1-11 ◽  
Author(s):  
Julian C. Hong ◽  
Donna Niedzwiecki ◽  
Manisha Palta ◽  
Jessica D. Tenenbaum

Purpose Patients undergoing radiotherapy (RT) or chemoradiotherapy (CRT) may require emergency department evaluation or hospitalization. Early identification may direct preventative supportive care, improving outcomes and reducing health care costs. We developed and evaluated a machine learning (ML) approach to predict these events. Methods A total of 8,134 outpatient courses of RT and CRT from a single institution from 2013 to 2016 were identified. Extensive pretreatment data were programmatically extracted and processed from the electronic health record (EHR). Training and internal validation cohorts were randomly generated (3:1 ratio). Gradient tree boosting (GTB), random forest, support vector machine, and least absolute shrinkage and selection operator logistic regression approaches were trained and internally validated based on area under receiver operating characteristic (AUROC) curve. The most predictive ML approach was also evaluated using only disease- and treatment-related factors to assess predictive gain of extensive EHR data. Results All methods had high predictive accuracy, particularly GTB (validation AUROC, 0.798). Extensive EHR data beyond disease and treatment information improved accuracy (delta AUROC, 0.056). A Youden-based cutoff corresponded to validation sensitivity of 81.0% (175 of 216 courses with events) and specificity of 67.3% (1,218 of 1811 courses without events). Interpretability is an important advantage of GTB. Variable importance identified top predictive factors, including treatment (planned RT and systemic therapy), pretreatment encounters (emergency department visits and admissions in the year before treatment), vital signs (weight loss and pain score in the year before treatment), and laboratory values (albumin level at weeks before treatment). Conclusion ML predicts emergency visits and hospitalization during cancer therapy. Incorporating predictions into clinical care algorithms may help direct personalized supportive care, improve quality of care, and reduce costs. A prospective trial investigating ML-assisted direction of increased clinical assessments during RT is planned.

2016 ◽  
Vol 33 (S1) ◽  
pp. S84-S84
Author(s):  
E. Albuquerque ◽  
S. Fernandes ◽  
J. Cerejeira

IntroductionInnovative approaches are needed to respond to the increasing number of elderly subjects with complex psychiatric conditions who require flexible and rapid responses, avoiding unnecessary hospital admissions. A new organizational model was implemented in our psychogeriatric service in September 2011 consisting of:– a comprehensive multidisciplinary geriatric assessment;– a helpline for caregivers for management of acute behavioral problems;– programmed visits to nursing homes.AimsTo evaluate whether the implementation of this program was associated with a reduction in hospital admissions and emergency department visits.MethodsThis is a pre-post test design study, involving 1197 patients who attended the Old Age Psychiatric (OAP) Unit three years before and three years after the implementation of the organizational intervention (1.09.2008 to 1.10.2014). An index of patient × year was calculated considering the period during which the patient was followed in OAP Unit. Data was obtained from the medical files of all eligible patients regarding demographic variables, number and type of hospital admissions and emergency department visits.ResultsDuring the 3 years before the intervention 671.2 patients × years were included (mean age of 75.8 years) while after the intervention this reached 2010.1 patients × years (mean age of 77.8 years). The intervention was associated with a decrease of 44% in psychiatry emergency visits, 48% in general emergency visits, 44% in psychiatric ward admissions and 51% in geriatric ward admissions.ConclusionsThe implementation of this new model was associated with significant reduction of hospital-based service utilization. Future research should determine if this was coupled with increased health outcomes.Disclosure of interestThe authors have not supplied their declaration of competing interest.


Author(s):  
Abdullah Aldamigh ◽  
Afaf Alnefisah ◽  
Abdulrahman Almutairi ◽  
Fatima Alturki ◽  
Suhailah Alhtlany ◽  
...  

2019 ◽  
Vol 23 (1) ◽  
pp. 12-21 ◽  
Author(s):  
Shikha N. Khera ◽  
Divya

Information technology (IT) industry in India has been facing a systemic issue of high attrition in the past few years, resulting in monetary and knowledge-based loses to the companies. The aim of this research is to develop a model to predict employee attrition and provide the organizations opportunities to address any issue and improve retention. Predictive model was developed based on supervised machine learning algorithm, support vector machine (SVM). Archival employee data (consisting of 22 input features) were collected from Human Resource databases of three IT companies in India, including their employment status (response variable) at the time of collection. Accuracy results from the confusion matrix for the SVM model showed that the model has an accuracy of 85 per cent. Also, results show that the model performs better in predicting who will leave the firm as compared to predicting who will not leave the company.


2021 ◽  
Vol 10 (5) ◽  
pp. 992
Author(s):  
Martina Barchitta ◽  
Andrea Maugeri ◽  
Giuliana Favara ◽  
Paolo Marco Riela ◽  
Giovanni Gallo ◽  
...  

Patients in intensive care units (ICUs) were at higher risk of worsen prognosis and mortality. Here, we aimed to evaluate the ability of the Simplified Acute Physiology Score (SAPS II) to predict the risk of 7-day mortality, and to test a machine learning algorithm which combines the SAPS II with additional patients’ characteristics at ICU admission. We used data from the “Italian Nosocomial Infections Surveillance in Intensive Care Units” network. Support Vector Machines (SVM) algorithm was used to classify 3782 patients according to sex, patient’s origin, type of ICU admission, non-surgical treatment for acute coronary disease, surgical intervention, SAPS II, presence of invasive devices, trauma, impaired immunity, antibiotic therapy and onset of HAI. The accuracy of SAPS II for predicting patients who died from those who did not was 69.3%, with an Area Under the Curve (AUC) of 0.678. Using the SVM algorithm, instead, we achieved an accuracy of 83.5% and AUC of 0.896. Notably, SAPS II was the variable that weighted more on the model and its removal resulted in an AUC of 0.653 and an accuracy of 68.4%. Overall, these findings suggest the present SVM model as a useful tool to early predict patients at higher risk of death at ICU admission.


2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Linda A. Antonucci ◽  
Alessandra Raio ◽  
Giulio Pergola ◽  
Barbara Gelao ◽  
Marco Papalino ◽  
...  

Abstract Background Recent views posited that negative parenting and attachment insecurity can be considered as general environmental factors of vulnerability for psychosis, specifically for individuals diagnosed with psychosis (PSY). Furthermore, evidence highlighted a tight relationship between attachment style and social cognition abilities, a key PSY behavioral phenotype. The aim of this study is to generate a machine learning algorithm based on the perceived quality of parenting and attachment style-related features to discriminate between PSY and healthy controls (HC) and to investigate its ability to track PSY early stages and risk conditions, as well as its association with social cognition performance. Methods Perceived maternal and paternal parenting, as well as attachment anxiety and avoidance scores, were trained to separate 71 HC from 34 PSY (20 individuals diagnosed with schizophrenia + 14 diagnosed with bipolar disorder with psychotic manifestations) using support vector classification and repeated nested cross-validation. We then validated this model on independent datasets including individuals at the early stages of disease (ESD, i.e. first episode of psychosis or depression, or at-risk mental state for psychosis) and with familial high risk for PSY (FHR, i.e. having a first-degree relative suffering from psychosis). Then, we performed factorial analyses to test the group x classification rate interaction on emotion perception, social inference and managing of emotions abilities. Results The perceived parenting and attachment-based machine learning model discriminated PSY from HC with a Balanced Accuracy (BAC) of 72.2%. Slightly lower classification performance was measured in the ESD sample (HC-ESD BAC = 63.5%), while the model could not discriminate between FHR and HC (BAC = 44.2%). We observed a significant group x classification interaction in PSY and HC from the discovery sample on emotion perception and on the ability to manage emotions (both p = 0.02). The interaction on managing of emotion abilities was replicated in the ESD and HC validation sample (p = 0.03). Conclusion Our results suggest that parenting and attachment-related variables bear significant classification power when applied to both PSY and its early stages and are associated with variability in emotion processing. These variables could therefore be useful in psychosis early recognition programs aimed at softening the psychosis-associated disability.


2021 ◽  
pp. 1-17
Author(s):  
Ahmed Al-Tarawneh ◽  
Ja’afer Al-Saraireh

Twitter is one of the most popular platforms used to share and post ideas. Hackers and anonymous attackers use these platforms maliciously, and their behavior can be used to predict the risk of future attacks, by gathering and classifying hackers’ tweets using machine-learning techniques. Previous approaches for detecting infected tweets are based on human efforts or text analysis, thus they are limited to capturing the hidden text between tweet lines. The main aim of this research paper is to enhance the efficiency of hacker detection for the Twitter platform using the complex networks technique with adapted machine learning algorithms. This work presents a methodology that collects a list of users with their followers who are sharing their posts that have similar interests from a hackers’ community on Twitter. The list is built based on a set of suggested keywords that are the commonly used terms by hackers in their tweets. After that, a complex network is generated for all users to find relations among them in terms of network centrality, closeness, and betweenness. After extracting these values, a dataset of the most influential users in the hacker community is assembled. Subsequently, tweets belonging to users in the extracted dataset are gathered and classified into positive and negative classes. The output of this process is utilized with a machine learning process by applying different algorithms. This research build and investigate an accurate dataset containing real users who belong to a hackers’ community. Correctly, classified instances were measured for accuracy using the average values of K-nearest neighbor, Naive Bayes, Random Tree, and the support vector machine techniques, demonstrating about 90% and 88% accuracy for cross-validation and percentage split respectively. Consequently, the proposed network cyber Twitter model is able to detect hackers, and determine if tweets pose a risk to future institutions and individuals to provide early warning of possible attacks.


Sensors ◽  
2021 ◽  
Vol 21 (2) ◽  
pp. 617
Author(s):  
Umer Saeed ◽  
Young-Doo Lee ◽  
Sana Ullah Jan ◽  
Insoo Koo

Sensors’ existence as a key component of Cyber-Physical Systems makes it susceptible to failures due to complex environments, low-quality production, and aging. When defective, sensors either stop communicating or convey incorrect information. These unsteady situations threaten the safety, economy, and reliability of a system. The objective of this study is to construct a lightweight machine learning-based fault detection and diagnostic system within the limited energy resources, memory, and computation of a Wireless Sensor Network (WSN). In this paper, a Context-Aware Fault Diagnostic (CAFD) scheme is proposed based on an ensemble learning algorithm called Extra-Trees. To evaluate the performance of the proposed scheme, a realistic WSN scenario composed of humidity and temperature sensor observations is replicated with extreme low-intensity faults. Six commonly occurring types of sensor fault are considered: drift, hard-over/bias, spike, erratic/precision degradation, stuck, and data-loss. The proposed CAFD scheme reveals the ability to accurately detect and diagnose low-intensity sensor faults in a timely manner. Moreover, the efficiency of the Extra-Trees algorithm in terms of diagnostic accuracy, F1-score, ROC-AUC, and training time is demonstrated by comparison with cutting-edge machine learning algorithms: a Support Vector Machine and a Neural Network.


Sign in / Sign up

Export Citation Format

Share Document