scholarly journals QIS: A Framework for Biomedical Database Federation

2004 ◽  
Vol 11 (6) ◽  
pp. 523-534 ◽  
Author(s):  
Luis Marenco ◽  
Tzuu-Yi Wang ◽  
Gordon Shepherd ◽  
Perry L. Miller ◽  
Prakash Nadkarni
Keyword(s):  
Author(s):  
Ralf Böttger ◽  
Yaron Engel ◽  
Gerd Kachel ◽  
Silvia Kolmschlag ◽  
Dietmar Nolte ◽  
...  
Keyword(s):  

2009 ◽  
pp. 1442-1465
Author(s):  
Yu Jiao ◽  
Ali Hurson ◽  
Thomas E. R. Potok ◽  
Barbara G. Beckerman

In this chapter, we discuss issues related to ehealth and focus on two major challenges in distributed healthcare database management: database heterogeneity and user mobility. We designed and prototyped a mobile-agent-based mobile data-access system framework that can address these challenges. It applies a thesaurus- based hierarchical database federation to cope with database heterogeneity and utilizes the mobile-agent technology to respond to the complications introduced by user mobility and wireless networks. The functions provided by this system are described in detail and a performance evaluation is also provided.


2009 ◽  
pp. 484-504
Author(s):  
Yu Jiao ◽  
Ali R. Hurson ◽  
Thomas E. Potok ◽  
Barbara G. Beckerman

In this chapter, we discuss issues related to ehealth and focus on two major challenges in distributed healthcare database management: database heterogeneity and user mobility. We designed and prototyped a mobile-agent-based mobile data-access system framework that can address these challenges. It applies a thesaurus- based hierarchical database federation to cope with database heterogeneity and utilizes the mobile-agent technology to respond to the complications introduced by user mobility and wireless networks. The functions provided by this system are described in detail and a performance evaluation is also provided.


2005 ◽  
Vol 44 (02) ◽  
pp. 257-261
Author(s):  
Y. Tohsato ◽  
S. Date ◽  
H. Matsuda ◽  
S. Shimojo ◽  
T. Kosaka

Summary Objectives: The rapid progress of life-scientific research has the potential to dramatically change the paradigm of drug discovery. Efficient utilization of life-scientific resources, i.e., databases and analytic software tools, poses a challenging issue with regard to the reduction of time and cost in the drug discovery process. In this paper, a variety of heterogeneous Web-based life-scientific resources are integrated toward the improvement of drug discovery performance. Methods: For the integration of heterogeneous life-scientific resources, a database federation technique based on three-layer architecture has been utilized. With the federation technique, life-scientific resources are integrated step by step through database layers, database integration layers and analysis layers to encapsulate complexity and heterogeneity. In this study, we have taken advantage of the latest Grid technology based on OGSA (Open Grid Services Architecture) for the implementation of our approach. Results: The actual case of life-scientific resources for drug discovery demonstrates that our prototype system developed with the proposed technique works well for the identification process of candidate compounds to a target protein. In other words, the prototype system allows a researcher to retrieve candidate compounds with less effort than before. Conclusions: The usefulness of the prototypic system represents the ability of our approach to integrate heterogeneous life-scientific resources, which have the potential to dramatically improve efficiency in drug discovery, resulting in the shortening of drug development. On the other hand, the system requires further consideration from the aspect of practical use. Dynamic aggregation of the resources is one example of such a consideration.


Author(s):  
Yu Jiao ◽  
Ali R. Hurson ◽  
Thomas E. Potok ◽  
Barbara G. Beckerman

In this chapter, we discuss issues related to e-health and focus on two major challenges in distributed healthcare database management: database heterogeneity and user mobility. We designed and prototyped a mobile-agent-based mobile data-access system framework that can address these challenges. It applies a thesaurus-based hierarchical database federation to cope with database heterogeneity and utilizes the mobile-agent technology to respond to the complications introduced by user mobility and wireless networks. The functions provided by this system are described in detail and a performance evaluation is also provided.


2002 ◽  
Vol 41 (4) ◽  
pp. 578-596 ◽  
Author(s):  
L. M. Haas ◽  
E. T. Lin ◽  
M. A. Roth

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