Development of Generalized Fragility Functions for Seismically Induced Content Disruption

2016 ◽  
Vol 32 (3) ◽  
pp. 1303-1324 ◽  
Author(s):  
Jean C. Guzman Pujols ◽  
Keri L. Ryan

This paper reports on the evaluation of the response of unanchored building contents in two separate shaking experiments, with the goal of developing simplified seismic fragility functions to be used for content disruption. The content response was evaluated collectively, by defining qualitative categorical ratings of overall content disruption based on observation of specific behaviors, such as sliding, toppling, rolling, or falling. Next, these disruption ratings were correlated to demand parameters, such as peak floor acceleration and peak floor velocity. Fragility functions were developed by combining two alternative implementations of the bounding demand data method. Among the demand parameters evaluated, peak floor velocity is shown to be a consistent indicator of disruption when comparing results from the two independent data sets. Vertical acceleration is shown to also influence the demand intensities that trigger disruption.

2019 ◽  
Author(s):  
Jessie Martin ◽  
Jason S. Tsukahara ◽  
Christopher Draheim ◽  
Zach Shipstead ◽  
Cody Mashburn ◽  
...  

**The uploaded manuscript is still in preparation** In this study, we tested the relationship between visual arrays tasks and working memory capacity and attention control. Specifically, we tested whether task design (selection or non-selection demands) impacted the relationship between visual arrays measures and constructs of working memory capacity and attention control. Using analyses from 4 independent data sets we showed that the degree to which visual arrays measures rely on selection influences the degree to which they reflect domain-general attention control.


BMC Cancer ◽  
2007 ◽  
Vol 7 (1) ◽  
Author(s):  
James E Korkola ◽  
Ekaterina Blaveri ◽  
Sandy DeVries ◽  
Dan H Moore ◽  
E Shelley Hwang ◽  
...  

2000 ◽  
Vol 55 (5-6) ◽  
pp. 399-409 ◽  
Author(s):  
Olivier Raymond ◽  
Jean-Louis Fiasson ◽  
Maurice Jay

Fifteen Rosa cultivated races were described by means of phenotypic frequencies (11 tables). Two groups of correlated contingency tables were identified by ACT-STATIS (Analyse Conjointe de Tableaux - Structuration de Tableaux à Trois Indices de la Statistique) interstructure analysis. Three data sets appeared to be independent from the others. Typologies of races were obtained after ACT-STATIS compromise analyses for the two groups of correlated tables, and after Principal Component Analyses for the independent data sets. Each typology was original and variously influenced by genealogical structure, mutation or artificial selection pressures. A weighted synthesis was attempted in order to build a taxonomy of races taking into account these diversity factors. The good agreement between the resulting classification and the assumptions about the history of Rosa domestication advocated for a wider utilization of ACT-STATIS and RV coefficient when the relationships between individuals or populations have to be studied on the basis of their similarities.


2020 ◽  
Vol 16 ◽  
pp. 117693432092056
Author(s):  
Shuping Qu ◽  
Qiuyuan Shi ◽  
Jing Xu ◽  
Wanwan Yi ◽  
Hengwei Fan

This study was aimed at revealing the dynamic regulation of mRNAs, long noncoding RNAs (lncRNAs), and microRNAs (miRNAs) in hepatocellular carcinoma (HCC) and to identify HCC biomarkers capable of predicting prognosis. Differentially expressed mRNAs (DEmRNAs), lncRNAs, and miRNAs were acquired by comparing expression profiles of HCC with normal samples, using an expression data set from The Cancer Genome Atlas. Altered biological functions and pathways in HCC were analyzed by subjecting DEmRNAs to Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis. Gene modules significantly associated with disease status were identified by weighted gene coexpression network analysis. An lncRNA-mRNA and an miRNA-mRNA coexpression network were constructed for genes in disease-related modules, followed by the identification of prognostic biomarkers using Kaplan-Meier survival analysis. Differential expression and association with the prognosis of 4 miRNAs were verified in independent data sets. A total of 1220 differentially expressed genes were identified between HCC and normal samples. Differentially expressed mRNAs were significantly enriched in functions and pathways related to “plasma membrane structure,” “sensory perception,” “metabolism,” and “cell proliferation.” Two disease-associated gene modules were identified. Among genes in lncRNA-mRNA and miRNA-mRNA coexpression networks, 9 DEmRNAs and 7 DEmiRNAs were identified to be potential prognostic biomarkers. MIMAT0000102, MIMAT0003882, and MIMAT0004677 were successfully validated in independent data sets. Our results may advance our understanding of molecular mechanisms underlying HCC. The biomarkers may contribute to diagnosis in future clinical practice.


1997 ◽  
Vol 14 (2) ◽  
pp. 53-58 ◽  
Author(s):  
Gary W. Fowler

Abstract New total, pulpwood, sawtimber, and residual pulpwood cubic foot individual tree volume equations were developed for red pine in Michigan using nonlinear and multiple linear regression. Equations were also developed for Doyle, International 1/4 in., and Scribner bd ft volume, and a procedure for estimating pulpwood and residual pulpwood rough cord volumes from the appropriate cubic foot equations was described. Average ratios of residual pulpwood (i.e., topwood, cubic foot or cords) to mbf were developed for 7.6 and 9.6 in. sawtimber. Data used to develop these equations were collected during May-August 1983-1985 from 3,507 felled and/or standing trees from 27 stands in Michigan. Sixteen and 11 stands were located in the Upper and Lower Peninsulas, respectively. All equations were validated on an independent data set. Rough cord volume estimates based on the new pulpwood equation were compared with contemporary tables for 2 small cruise data sets. The new equations can be used to more accurately estimate total volume and volume per acre when cruising red pine stands. North. J. Appl. For. 14(2):53-58.


2019 ◽  
Vol 2019 ◽  
pp. 1-17 ◽  
Author(s):  
Zhiming He ◽  
Qingjun Chen

The measured vertical peak ground acceleration was larger than the horizontal peak ground acceleration. It is essential to consider the vertical seismic effect in seismic fragility evaluation of large-space underground structures. In this research, an approach is presented to construct fragility curves of large-space underground structures considering the vertical seismic effect. In seismic capacity, the soil-underground structure pushover analysis method which considers the vertical seismic loading is used to obtain the capacity curve of central columns. The thresholds of performance levels are quantified through a load-drift backbone curve model. In seismic demand, it is evaluated through incremental dynamic analysis (IDA) method under the excitation of horizontal and vertical acceleration, and the soil-structure-interaction and ground motion characteristics are also considered. The IDA results are compared in terms of peak ground acceleration and peak ground velocity. To construct the fragility curves, the evolutions of performance index versus the increasing earthquake intensity are performed, considering related uncertainties. The result indicates that if we ignore the vertical seismic effect to the fragility assessment of large-space underground structures, the exceedance probabilities of damage of large-space underground structures will be underestimated, which will result in an unfavorable assessment result.


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