When mountains weep: psychological care for those affected by the earthquake in northern Pakistan

Murad M. Khan

doi:10.1192/pb.30.12.454

When mountains weep: psychological care for those affected by the earthquake in northern Pakistan

Psychiatric Bulletin ◽

10.1192/pb.30.12.454 ◽

2006 ◽

Vol 30 (12) ◽

pp. 454-456 ◽

Cited By ~ 2

Author(s):

Murad M. Khan

Keyword(s):

Group Dynamics ◽

Substance Misuse ◽

Interpersonal Relationship ◽

Day Hospital ◽

Northern Pakistan ◽

Psychological Care ◽

Reality Testing ◽

Rotation Scheme ◽

To Come ◽

The Uk

Fate, it seems, conjures up all sorts of ways for us to be in a certain place at a certain time. In 1982 as a trainee psychiatrist in the UK, I found myself co-facilitating a group at the Castlewood Day Hospital, then part of the Bexley psychiatric rotation scheme, in the south-east of London. Group psychotherapy was part of our training. Held thrice a week the groups were open-ended and patients ranged from those with interpersonal relationship and personality problems to those with anxiety and substance misuse problems. At the time the experience was somewhat baffling. Not only was I from a different country and culture, my exposure to psychiatry was limited to about 12 months. More often than not I felt lost as I tried to come to terms with ‘group dynamics', ‘reality testing’, ‘transference’, ‘multiple transference’, ‘group cohesion’, ‘group pressure’, etc.

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Diarylureas: Repositioning from Antitumor to Antimicrobials or Multi-Target Agents against New Pandemics

Antibiotics ◽

10.3390/antibiotics10010092 ◽

2021 ◽

Vol 10 (1) ◽

pp. 92 ◽

Cited By ~ 2

Author(s):

Alessia Catalano ◽

Domenico Iacopetta ◽

Michele Pellegrino ◽

Stefano Aquaro ◽

Carlo Franchini ◽

...

Keyword(s):

Anticancer Agents ◽

Kinase Inhibitors ◽

Viral Infections ◽

Drug Repositioning ◽

Biological Activities ◽

Antiviral Treatment ◽

Far East ◽

Mild Disease ◽

To Come ◽

The Uk

Antimicrobials have allowed medical advancements over several decades. However, the continuous emergence of antimicrobial resistance restricts efficacy in treating infectious diseases. In this context, the drug repositioning of already known biological active compounds to antimicrobials could represent a useful strategy. In 2002 and 2003, the SARS-CoV pandemic immobilized the Far East regions. However, the drug discovery attempts to study the virus have stopped after the crisis declined. Today’s COVID-19 pandemic could probably have been avoided if those efforts against SARS-CoV had continued. Recently, a new coronavirus variant was identified in the UK. Because of this, the search for safe and potent antimicrobials and antivirals is urgent. Apart from antiviral treatment for severe cases of COVID-19, many patients with mild disease without pneumonia or moderate disease with pneumonia have received different classes of antibiotics. Diarylureas are tyrosine kinase inhibitors well known in the art as anticancer agents, which might be useful tools for a reposition as antimicrobials. The first to come onto the market as anticancer was sorafenib, followed by some other active molecules. For this interesting class of organic compounds antimicrobial, antiviral, antithrombotic, antimalarial, and anti-inflammatory properties have been reported in the literature. These numerous properties make these compounds interesting for a new possible pandemic considering that, as well as for other viral infections also for CoVID-19, a multitarget therapeutic strategy could be favorable. This review is meant to be an overview on diarylureas, focusing on their biological activities, not dwelling on the already known antitumor activity. Quite a lot of papers present in the literature underline and highlight the importance of these molecules as versatile scaffolds for the development of new and promising antimicrobials and multitarget agents against new pandemic events.

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Male psychosexual therapy in the UK military

Journal of the Royal Army Medical Corps ◽

10.1136/jramc-2018-001046 ◽

2019 ◽

Vol 165 (2) ◽

pp. 94-97

Author(s):

Clair Clifford ◽

M McCauley

Keyword(s):

Service Life ◽

Military Personnel ◽

Surgical Complications ◽

Interpersonal Relationship ◽

Psychological Trauma ◽

Physical Injury ◽

Professional Help ◽

Life Context ◽

The Uk ◽

Therapy Service

Military personnel can experience psychosexual difficulties for a variety of reasons. Problems can arise because of psychological trauma, physical injury, consequences arising from pharmacological and surgical complications and social or emotional concerns relating to intrapersonal and interpersonal relationship dynamics. Such individuals might seek to minimise or avoid resolving their pertinent difficulties, while others can experience cultural, personal or organisational barriers to accessing professional help. This paper offers an overview of the development of a national specialist psychosexual therapy service (PST), commenting specifically on the service delivery for male military personnel. It will also consider factors which may support progress in treatment and reflect upon the importance of considering psychosexual functioning in relationships as part of the broader service-life context, which is especially relevant to military personnel.

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Achieving digital health sustainability: Breaking Free and CGL

International Journal of Health Governance ◽

10.1108/ijhg-07-2016-0037 ◽

2017 ◽

Vol 22 (2) ◽

pp. 72-82 ◽

Cited By ~ 2

Author(s):

Jonathan Ward ◽

Glyn Davies ◽

Stephanie Dugdale ◽

Sarah Elison ◽

Prun Bijral

Keyword(s):

Free Group ◽

Substance Misuse ◽

Digital Health ◽

Health Sector ◽

Third Sector ◽

Computer Assisted ◽

Behavioural Science ◽

Content Type ◽

Health And Social Care ◽

The Uk

Purpose Multiple challenges remain in achieving sustainability of digital health innovations, with many failing to realise their potential due to barriers to research, development and implementation. Finding an approach that overcomes these challenges is important if society is to derive benefit from these new approaches to healthcare. Having been commissioned by local authorities, NHS Trusts, prisons, charities, and third sector providers across the UK, Breaking Free Group, who in 2010 launched Breaking Free Online (BFO), a computer-assisted therapy programme for substance misuse, have overcome many of these challenges. This has been possible through close collaborative working with partner organisations, to overcome barriers to implementation and sustainability. The paper aims to discuss these issues. Design/methodology/approach This paper synthesises findings from a series of qualitative studies conducted by Breaking Free Group in collaboration with health and social care charity, Change, Grow, Live (CGL), which explore barriers and facilitators of implementation and sustainability of BFO at CGL. Data are analysed using thematic analyses with findings conceptualised using behavioural science theory. Findings This partnership has resulted in UK wide implementation of BFO at CGL, enhanced focus on digital technologies in substance misuse recovery, and a growing body of published collaborative research. Originality/value Valuable lessons have been learnt through the partnership between Breaking Free Group and CGL, which will be of interest to the wider digital health community. This paper outlines those lessons, in the hope that they will provide guidance to other digital health developers and their partners, to contribute to the continued evolution of a sustainable digital health sector.

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Overseas doctors' training scheme

Psychiatric Bulletin ◽

10.1192/pb.16.11.701 ◽

1992 ◽

Vol 16 (11) ◽

pp. 701-702

Author(s):

R. A. Adeniran

Keyword(s):

Training Programme ◽

Training Scheme ◽

Early Arrival ◽

Pertinent Information ◽

To Come ◽

The Uk

About a year after applying to come on the Overseas Doctors' Training Scheme (ODTS), I was offered a post. The letter arrived about two months before I was to start work in the UK; it contained pertinent information about my job, the training programme, and the community I would live in. The information and its early arrival enabled me to make adequate preparation for my trip.

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Pharmacogenomics in the UK National Health Service: opportunities and challenges

Pharmacogenomics ◽

10.2217/pgs-2020-0091 ◽

2020 ◽

Vol 21 (17) ◽

pp. 1237-1246

Author(s):

Richard M Turner ◽

William G Newman ◽

Elvira Bramon ◽

Christine J McNamee ◽

Wai Lup Wong ◽

...

Keyword(s):

National Health Service ◽

Health Service ◽

National Health ◽

Genomic Medicine ◽

Improve Patient Care ◽

Healthcare Sector ◽

Patient Representatives ◽

To Come ◽

Uk National Health Service ◽

The Uk

Despite increasing interest in pharmacogenomics, and the potential benefits to improve patient care, implementation into clinical practice has not been widespread. Recently, there has been a drive to implement genomic medicine into the UK National Health Service (NHS), largely spurred on by the success of the 100,000 Genomes Project. The UK Pharmacogenetics and Stratified Medicine Network, NHS England and Genomics England invited experts from academia, the healthcare sector, industry and patient representatives to come together to discuss the opportunities and challenges of implementing pharmacogenomics into the NHS. This report highlights the discussions of the workshop to provide an overview of the issues that need to be considered to enable pharmacogenomic medicine to become mainstream within the NHS.

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The rate and impact of substance misuse in psychiatric intensive care units (PICUs) in the UK

Advances in Dual Diagnosis ◽

10.1108/add-06-2021-0008 ◽

2021 ◽

Vol ahead-of-print (ahead-of-print) ◽

Author(s):

Hattie Catherine Ann Moyes ◽

Lana MacNaboe ◽

Kate Townsend

Keyword(s):

Intensive Care ◽

Intensive Care Units ◽

Substance Misuse ◽

Well Being ◽

Training Programme ◽

Content Type ◽

National Quality ◽

Improvement Programme ◽

The Uk ◽

The Impact

Purpose This paper aims to understand the current scale of substance misuse in psychiatric intensive care units (PICUs), identify how substance misuse affects members of staff, patients and the running of wards and explore with staff what resources would be most useful to more effectively manage substance misuse and dual diagnosis on PICUs. Design/methodology/approach The paper used a mixed-methods approach, using a quantitative survey to determine the extent of substance use in PICUs and a co-design workshop to understand the impact of substance misuse on PICU wards, staff and patients. Findings The estimated rate of substance misuse in PICUs over a 12-month period is 67%, with cannabis the most frequently used substance. Despite the range of problems experienced on PICUs because of substance misuse, the availability of training and resources for staff was mixed. Research limitations/implications The findings may not be fully generalisable as research participants were members of a national quality improvement programme, and therefore, may not be representative of all PICUs. Data was collected from clinicians only; if patients were included, they might have provided another perspective on substance misuse on PICUs. Practical implications This paper emphasises the importance of substance misuse training for PICU staff to adequately respond to patients who misuse substances, improve the ward environment, staff well-being and patient outcomes. Originality/value This paper provides an updated estimation of rates of substance misuse in PICUs over a 12-month period and make suggestions for a training programme that can better support staff to address substance misuse on PICUs.

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A Science So-Called

10.1093/oso/9780192898975.003.0002 ◽

2021 ◽

pp. 21-55

Author(s):

Megan Faragher

Keyword(s):

Social Psychology ◽

Group Dynamics ◽

Film Adaptation ◽

Inherent Difficulty ◽

Group Psychology ◽

The World ◽

To Come ◽

The University ◽

The Universe

H.G. Wells’s life extends the radical evolution of psychographics outlined in the Introduction, but his oeuvre also proves the inherent difficulty in aestheticizing the emergent age of social psychology—a point evinced when producer Alexander Korda demanded Wells revise the script version of his 1933 novel The Shape of Things to Come three times to make it “filmable.” While Wells’s novel imagines a peaceable future wherein social psychology becomes the “whole literature, philosophy, and general thought of the world,” the film adaptation instead symbolizes this philosophical transformation by starring a sole philosopher-king who, against the people’s will, seeks to control and colonize the universe. This chapter argues that the conflict between these two Wellsian visions is prefigured by his intimate and conflicted relationship to sociology and group psychology. As early as 1906, Wells sought out the position as the first British chair of sociology at the University of London. But Wells was immediately to become a gadfly in academia: he engaged in scathing critiques of sociology for denying its utopian impulses and refuted theories of group dynamics put forward by Gustave Le Bon and Wilfred Trotter. Incorporating readings across Wells’s literary career—including Anticipations, An Englishman Looks at the World, and In the Days of the Comet—this chapter contends that Wells’s writing captures a life-long effort to reprise the scope of sociology from outside academia, and captures the writer’s foundering efforts to aestheticize the institutional promise of social psychology—efforts that inevitably succumb to Wells’s fetishization of pseudo-authoritarian technocracy.

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14. Key elements of the patent system

Information Technology Law ◽

10.1093/he/9780198830559.003.0014 ◽

2020 ◽

pp. 230-245

Author(s):

Ian J. Lloyd

Keyword(s):

Patent Protection ◽

World Trade Organisation ◽

Patent System ◽

The European Union ◽

The United Kingdom ◽

System P ◽

To Come ◽

The Uk ◽

Near Future

This chapter considers the nature and manner of operation of the patent system. Patents date back to around the 14th century. For the United Kingdom they began as a means to encourage the importation of foreign skills and technology, fell into disrepute as they were used by monarchs to confer monopolies in respect of the sale of well-known objects such as playing cards and eventually from the late seventeenth century settled into their present role of granting temporary monopolies to those who make inventions. The chapter examines the criteria that will be applied in determining whether an invention is eligible for patent protection and the procedures that will required to be followed in order to obtain this. Unlike copyright which applies effectively on a global basis, the patent system has operated on a national basis. A UK patent will be valid and enforceable in the UK but nowhere else. There are international agreements, however, designed to simplify the task of obtaining protection in a range of countries and the operation of these will be considered as well as the treatment of intellectual property within the General Agreement on Trade in Services and the World Trade Organisation. Within the European Union, the possible introduction of a unitary patent has been the subject of discussion for many years and appears likely to come to fruition in the near future although the involvement of the UK post Brexit is uncertain.

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Size and Persistence of Nitrous Oxide Hot-Spots in Grazed and Ungrazed Grassland

Environment and Natural Resources Research ◽

10.5539/enrr.v5n4p1 ◽

2015 ◽

Vol 5 (4) ◽

pp. 1 ◽

Cited By ~ 3

Author(s):

Paul R. Hargreaves ◽

Robert M. Rees ◽

Graham W. Horgan ◽

Bruce C. Ball

Keyword(s):

Nitrous Oxide ◽

Soil Temperature ◽

Hot Spots ◽

Hot Spot ◽

Nutrient Input ◽

Young Stock ◽

Spatial And Temporal Heterogeneity ◽

The Mean ◽

To Come ◽

The Uk

Nitrous oxide (N2O) emissions from agriculture contributed an estimated 60% of the global total in 2005. In the UK, grassland soils account for 30% of total emissions, 22% of which are estimated to come from urine and dung patches. These patches are possible sources of ‘hot-spots’ (area ca. 1 m2) of N2O fluxes. Spatial and temporal heterogeneity of N2O hot-spot fluxes were investigated in three grassland fields (grazed with dairy cows (DG), grazed with young stock (YG) or cut for silage (SC)) using gas sampling chambers surrounding historic hot-spots to establish their size. Fluxes from old dung and urine patches were measured, as well as freshly applied dung and urine to simulate the creation of hot-spots. Potential chemical and physical drivers were also measured. Large spatial variability of N2O fluxes was seen in all three grassland fields. Mean N2O fluxes for the historic hot-spots in the grazed fields (DG and YG) were significantly greater than (SC). The mean N2O fluxes in DG and YG (117.9 and 243.5 ng N m-2 s-1) were 15 to 30% greater than for SC. Soil temperature (15 - 20 °C) was the most significant driver of N2O production with a 1°C rise in soil temperature increasing emissions under DG and YG. N2O fluxes were enhanced by the fresh dung but not by urine. However, in the urine treatment, the nutrient input increased the microbial respiration response for the CO2 flux. Hot-spot N2O emissions from old urine and dung patches were persistent several months after application.

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