Relation of Histamine Headache to Post-Contusional and Psychogenic Headache

1945 ◽  
Vol 91 (383) ◽  
pp. 213-216 ◽  
Author(s):  
M. N. Pai
Keyword(s):  
Intravenous Injection ◽  
Migraine Headache ◽  
Recurrent Headache ◽  
The Third ◽  
Psychogenic Headaches

Von Storch has induced headache by the sudden intravenous injection of minute amounts of histamine phosphate in three groups of persons—the first group consisting of those subject to migraine, the second group composed of those suffering from chronic recurrent non-migraine headache, and the third group consisting of those not subject to headache. He has found that in persons subject to migraine the headache produced by histamine is frequently similar in character to their habitual headache (though bilateral), while in those subject to chronic recurrent non-migraine headache the experimental headache is only occasionally similar to their usual headache. From the evidence presented by him, linking migraine and histamine, the latter would appear to be a useful drug for distinguishing migraine from other forms of recurrent headache. Using a technique similar to his, experiments were performed at this centre to determine the relation of histamine headache to post-contusional and psychogenic headaches, and the results are worth recording.

Structural and Neurochemical Markers of Brain Injury in the Migraine Diathesis of Systemic Lupus Erythematosus

Cephalalgia ◽  
1998 ◽  
Vol 18 (4) ◽  
pp. 209-215 ◽  
Author(s):  
CL Rozell ◽  
WL Sibbitt ◽  
WM Brooks
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Brain Injury ◽  
Disease Activity ◽  
Lupus Erythematosus ◽  
Migraine Headache ◽  
Organ Involvement ◽  
Systemic Lupus ◽  
Recurrent Headache ◽  
Patients At Risk ◽  
Magnetic Resonance Imaging Mri

Objective: To determine whether migraine in systemic lupus erythematosus (SLE) is associated with accentuated brain injury and disease activity. Methods: Forty SLE patients (11 without headache, 11 with non-migraine headache, and 18 with migraine) underwent clinical evaluation, magnetic resonance imaging (MRI), and spectroscopy (MRS). Results: Recurrent headache occurred in 75% of SLE patients. MRI abnormalities and reduced N-acetylaspartate were common. However, migraine in SLE was not associated with increased disease activity or severity, neuropsychiatrie manifestations, or end-organ involvement compared to patients without migraine ( p>0.05). There were no differences in the prevalence or severity of MRI or MRS abnormalities between SLE patients with migraine, with non-migraine headache, or without headache ( p>0.05). Conclusions: Headache does not identify SLE patients at risk for brain injury, increased disease activity, or increased end-organ involvement. Aggressive immunosuppressive therapy for headache alone is not indicated in SLE.

scholarly journals Recurrent headache and migraine within the family

Genetika ◽  
2011 ◽  
Vol 43 (1) ◽  
pp. 101-112
Author(s):  
Marija Knezevic-Pogancev
Keyword(s):  
Ethnic Groups ◽  
Clinical Picture ◽  
Migraine Headache ◽  
Nuclear Family ◽  
Family Data ◽  
Northern Province ◽  
Place Of Birth ◽  
Recurrent Headache ◽  
Migraine Headaches ◽  
The Family

The aim of this research was to determine risk for family appearance of the recurrent headache (non-migraine and migraine). The recurrent headache can be understood as being a heterogeneous state, consisting of some more, still not found, hereditary disposition factors which altogether, interacting with surrounding factors give the recognizable clinical picture. The current heredity concept suggests multifactor heredity. The research was conducted in Vojvodina, the Northern Province of Serbia. The population of Vojvodina is around 2 million people belonging to more than 20 different ethnic groups. During the 20 years period (1988-2008), 30363 children aged 3 to 17 years were tested, independent of the place of birth. The presence of headaches similar to those tested was compared among all the members of the family within three generations. Positive family data of the recurrent headaches was detected among 98,6% children with migraine headaches, 64,7% children with non- migraine headaches, and 32,4% children without recurrent headaches. The relation among the members of the nuclear family (contingency quotient of 0,429) is significantly stronger than the relation to the members of wider family (contingency quotient of 0,338). The probability of a child having the migraine headache, and not the non-migraine one, is 0,664 for a mother, 0,644 for a father, 0,411 for a father`s mother, - 0,175 for a mother`s mother, 0,165 for a mother`s father, and - 0,102 for a father`s father having similar recurrent headaches.

ALTERATIONS IN THE GLUCOSE TRANSPORT MECHANISM IN PATIENTS WITH COMPLICATIONS OF BACTERIAL MENINGITIS

PEDIATRICS ◽  
1964 ◽  
Vol 34 (4) ◽  
pp. 491-502
Author(s):  
R. D. Brooke Williams
Keyword(s):  
Cerebrospinal Fluid ◽  
Bacterial Meningitis ◽  
Glucose Transport ◽  
Intravenous Injection ◽  
Transport Mechanism ◽  
Spinal Fluid ◽  
Normal Pattern ◽  
The Third ◽  
Glucose Diffusion

Glucose diffusion tests were made on 8 children with bacterial meningitis, in 7 [SEE TABLE IV AND FIG 8. IN SOURCE PDF] of whom the organism had been identified. The results of the tests were correlated with the outcome of the illness. Of 3 patients who recovered without sequelae the glucose diffusion patterns were normal in 2 cases, while the third case had somewhat low curves. In 4 cases of proven bacterial meningitis with complication all the tests were abnormal. Three of these were cases of proven hydrocephalus and there was a reversal of the normal pattern of diffusion for the entry of glucose into the cisternal and lumbar regions. An actual lowering of the cisternal glucose following the intravenous injection of glucose was observed in two cases with initial very low spinal fluid sugars. The hypothesis is proposed that alterations in the blood cerebrospinal fluid barrier perhaps due to increased metabolism of arachnoid lining cells or edema in [SEE FIG 9 IN SOURCE PDF] addition to the action of bacteria and leukocytes contribute to the persistent hypoglycorrhachia seen in complicated cases of bacterial meningitis.

scholarly journals Role of nitric oxide in systemic vasopressin-induced hypothermia

1998 ◽  
Vol 275 (4) ◽  
pp. R937-R941 ◽  
Author(s):  
Alexandre A. Steiner ◽  
Evelin C. Carnio ◽  
José Antunes-Rodrigues ◽  
Luiz G. S. Branco
Keyword(s):  
Nitric Oxide ◽  
Intravenous Injection ◽  
Induced Hypothermia ◽  
Basal Body Temperature ◽  
Systemic Injection ◽  
The Third ◽  
Before And After ◽  
Injection Control ◽  
Synthase Inhibitor

It has been reported that arginine vasopressin (AVP) plays a thermoregulatory action, but very little is known about the mechanisms involved. In the present study, we tested the hypothesis that nitric oxide (NO) plays a role in systemic AVP-induced hypothermia. Rectal temperature was measured before and after AVP, AVP blocker, or N G-nitro-l-arginine methyl ester (l-NAME; NO synthase inhibitor) injection. Control animals received saline injections of the same volume. The basal body temperature (Tb) measured in control animals was 36.53 ± 0.08°C. We observed a significant ( P < 0.05) reduction in Tb to 35.44 ± 0.19°C after intravenous injection of AVP (2 μg/kg) and to 35.74 ± 0.10°C after intravenous injection ofl-NAME (30 mg/kg). The systemic injection of the AVP blocker [β-mercapto-β,β-cyclopentamethylenepropionyl1, O-Et-Tyr2,Val4,Arg8]vasopressin (10 μg/kg) caused a significant increase in Tb to 37.33 ± 0.23°C, indicating that AVP plays a tonic role by reducing Tb. When the treatments with AVP and l-NAME were combined, systemically injected l-NAME blunted AVP-induced hypothermia. To assess the role of central thermoregulatory mechanisms, a smaller dose ofl-NAME (1 mg/kg) was injected into the third cerebral ventricle. Intracerebroventricular injection ofl-NAME caused an increase in Tb, but when intracerebroventricular l-NAME was combined with systemic AVP injection (2 μg/kg), no change in Tb was observed. The data indicate that central NO plays a major role mediating systemic AVP-induced hypothermia.

IDENTIFICATION AND SIGNIFICANCE OF PAROTID FLUID CORTICOSTEROIDS

1964 ◽  
Vol 46 (3) ◽  
pp. 393-404 ◽  
Author(s):  
Fred H. Katz ◽  
Ira L. Shannon
Keyword(s):  
Intravenous Injection ◽  
Cushing’S Syndrome ◽  
Cushing's Syndrome ◽  
Third Trimester ◽  
Acth Stimulation ◽  
The Third ◽  
Appreciable Quantity ◽  
Normal Men

ABSTRACT Parotid fluid, which can be collected in continuous fashion, was previously shown to possess free 17-hydroxycorticosteroid (17-OH-CS) levels which paralleled those in serum and reached a maximum two hours after corticotrophin or cortisol administration to normal men. The present study demonstrates that intravenously administered cortisol rapidly appears in parotid fluid, and that, thus, parotid fluid 17-OH-CS levels would serve as reliable indicators of plasma corticosteroid levels. This was borne out by ACTH stimulation studies in patients with Cushing's Syndrome as well as adrenal hyporesponsiveness. In the third trimester of pregnancy, despite the large rise in plasma 17-OH-CS, there was only a small, though significant, increase in parotid fluid 17-OH-CS. Conjugated 17-OH-CS were not found in appreciable quantity in parotid fluid. Chemical and radioisotopic techniques indicated cortisol and cortisone to be the major human parotid fluid 17-OH-CS. Parotid tissue from the dog converted cortisol to cortisone. Radioactive aldosterone, oestrogen and androgen also appeared in parotid fluid after intravenous injection.

Prevalence of Migraine in a Rural Area in South Tanzania: A door-to-door Survey

Cephalalgia ◽  
2004 ◽  
Vol 24 (11) ◽  
pp. 960-966 ◽  
Author(s):  
W Dent ◽  
HK Spiss ◽  
R Helbok ◽  
WBP Matuja ◽  
S Scheunemann ◽  
...  
Keyword(s):  
Rural Area ◽  
Prevalence Rate ◽  
Migraine Headache ◽  
Migraine Without Aura ◽  
International Headache Society ◽  
Face To Face ◽  
The Third ◽  
The Past ◽  
Representative Family ◽  
Affected Subject

We set out to assess the prevalence during the previous year of migraine in a rural area surrounding the Mnero Diocesan Hospital in Southern-Tanzania. A door-to-door survey from August until December 1999 using a questionnaire based on the criteria of the International Headache Society (IHS), including 1047 households with 3351 persons, was done, consisting of a screening dialogue with a representative family member followed by a face-to-face interview with the affected subject. Of the 3351 participants (female 1876; male 1475; age > 10 years), 23.1% had suffered from headache during the past year; overall prevalence of migraine was 5.0% (female 7.0%; male 2.6%); 1.4% reported migraine without aura (female 1.8%; male 0.9%); and 3.6% reported migraine with aura (female 5.2%, male 1.6%). The peak prevalence was found in female persons in the fourth (11.1%), in male persons in the third decade of life (3.8%). Compared with other African surveys, the prevalence rate of migraine headache in South Tanzania is slightly higher than among Ethiopian and Zimbabwean Africans.

Immunisation of sheep against Schistosoma mattheei using either irradiated cercariae or irradiated schistosomula

1976 ◽  
Vol 50 (1) ◽  
pp. 1-9 ◽  
Author(s):  
M. G. Taylor ◽  
E. R. James ◽  
G. S. Nelson ◽  
Q. Bickle ◽  
D. W. Dunne ◽  
...  
Keyword(s):  
Adult Worm ◽  
Intravenous Injection ◽  
Worm Burden ◽  
Intramuscular Injection ◽  
Challenge Infection ◽  
Pathological Changes ◽  
Degree Of Protection ◽  
The Third ◽  
Small Intestines ◽  
And Control

AbstractIrradiated cercariae, irradiated schistosomula, or hcterologous infections were used to vaccinate sheep against Schistosoma mattheei infection. In the first experiment four doses of I04 S. mattheei cercariae irradiated at 6Kr were administered to sheep by percutaneous infection at 4 week intervals. This induced a 74% reduction in a challenge infection compared to control sheep while only 13% protection was achieved in a third group of sheep immunised with normal cercariae of the heterologous parasite S. mansoni. No significant differences were seen in histopathology of the liver of any of the sheep but the pathological changes were more severe in the large and small intestines of sheep vaccinated with the heterologous parasite. In the second experiment with irradiated cercariae only one or two immunising exposures were used. The degree of protection in the adult worm load (9–11%) was not significant and no significant differences were noticed in the pathology of the vaccinated and control animals. In the third experiment four doses of irradiated organisms were used to vaccinate five groups of sheep: 3Kr or 6Kr cercariae were administered by percutaneous infection; 6Kr skin-transformed scbistosomula were administered by intramuscular injection; the same 6Kr skin-transformed schistosomula were given by intravenous injection and 6Kr syringe transformed schistosomula were administered by intramuscular injection. The degree of protection (determined as the reduction in worm burden) achieved by these different procedures was respectively 72%, 61%, 77%, 56% and 78%. These results indicate the possibility of making a live vaccine against ovine schistosomiasis and show that effective immunisation is not dependent on the presence of a mature worm infection or on cercarial penetration of the skin by the immunising infection.

scholarly journals A case of late-onset sporadic hemiplegic migraine

2019 ◽  
Vol 47 (10) ◽  
pp. 5278-5280
Author(s):  
Xiu-Yan Yang ◽  
Hua-Ping Du ◽  
Yuan Xu
Keyword(s):  
Migraine Headache ◽  
Late Onset ◽  
Hemiplegic Migraine ◽  
Rare Form ◽  
Cerebrospinal Fluid Analysis ◽  
Blurred Vision ◽  
Motor Weakness ◽  
Recurrent Headache ◽  
Fluid Analysis ◽  
Inflammatory Drugs

Sporadic hemiplegic migraine is a rare form of migraine headache with aura. We herein report a case of visual impairment, dizziness, and motor weakness in a patient who had experienced recurrent headache attacks with aura including flickering spots and blurred vision for 20 years, Electroencephalography, cerebrospinal fluid analysis, and brain imaging findings were normal. The patient gradually recovered after treatment with nonsteroidal anti-inflammatory drugs and flunarizine.

The Efficacy of Hypnotic and Nonhypnotic Response-Based Imagery for Self-Managing Recurrent Headache

1995 ◽  
Vol 14 (3) ◽  
pp. 183-201 ◽  
Author(s):  
Robert P. Nolan ◽  
Nicholas P. Spanos ◽  
Amber A. Hayward ◽  
Heather A. Scott
Keyword(s):  
Group Treatment ◽  
Migraine Headache ◽  
Tension Headache ◽  
Post Treatment ◽  
Control Group ◽  
Recurrent Headache ◽  
Imagery Training ◽  
Imagery Group ◽  
Medication Consumption

Two experiments investigated the use of hypnotic and nonhypnotic response-based imagery training for recurrent headache. In Experiment 1, subjects with symptoms of chronic migraine headache (CMH), or chronic mixed migraine/tension headache (Mixed CMH/CTH) were assigned to a Hypnotic or Nonhypnotic Imagery group, or to a Monitoring Control group. Treatment efficacy was assessed over two-week intervals, at Baseline, Post-treatment, and three successive follow-up periods. In Experiment 2, subjects with symptoms of chronic tension headache (CTH) were assigned to four conditions (Hypnotic Imagery/Nonhypnotic Imagery/Placebo/Monitoring Control), and studied across two-week intervals at Baseline, Post-treatment, and eight-week Follow-up. Hypnotic and Nonhypnotic Imagery conditions did not differ in demonstrating efficacy in reducing headache activity in both experiments. Treatment outcome was not associated with medication consumption, or actual changes in physiologic processes (cardiovascular functioning and frontalis EMG). Headache reduction was not correlated with hypnotizability or the trait propensity to engage in vivid imagery. These results replicate and extend previous findings, and support the use of imagery strategies as a treatment component in pain management programs.

Sign in / Sign up

Export Citation Format

Share Document