Investigation of the Acid-Base Balance in Mental Cases, with Special Reference to Epilepsy

1928 ◽  
Vol 74 (306) ◽  
pp. 454-459 ◽  
Author(s):  
Geoffrey Shera
Keyword(s):  
Sugar Content ◽  
Nitrogen Retention ◽  
Calcium Content ◽  
Blood Ammonia ◽  
Acid Base Balance ◽  
Acid Base ◽  
Ammonia Content ◽  
Blood Calcium ◽  
Negative Results ◽  
Base Balance

In the search for somatic disturbance in connection with the insane, either as a cause or as an effect of mental disorder, the acid-base balance has afforded a field of exploration from time to time. Epilepsy, in particular, has provided material for research on these lines. Bigwood (1) (1924) suggested that the epileptic seizure was preceded by an alkalosis, leading to a lowered blood-calcium content, which, in turn, induced the fit. Marrack and Thacker (2 and 3) (1926) disproved this theory, but found that a high blood-ammonia content obtained at times in epilepsy (4), but was not related to the fit. It was actually a starvation phenomenon. There has been biochemical work on other lines in epilepsy in regard to nitrogen retention (5) on the sugar content, but all with negative results.

THE SIGNIFICANCE OF PROTEIN SOLUBILITY IN BICARBONATE-INDUCED CHANGES IN NITROGEN UTILIZATION AND ACID-BASE BALANCE IN LAMBS

1986 ◽  
Vol 66 (3) ◽  
pp. 755-763
Author(s):  
M. V. ROGERS ◽  
L. E. PHILLIP
Keyword(s):  
Protein Solubility ◽  
Acid Stress ◽  
Latin Square ◽  
Nitrogen Retention ◽  
Acid Base Balance ◽  
Acid Base ◽  
N Retention ◽  
Base Balance ◽  
Induced Changes ◽  
Protein Diets

Six crossbred wether lambs were fed six isonitrogenous (15% protein) diets according to a 6 × 4 incomplete latin square with four 24-d periods. The diets were arranged as a 2 × 3 factorial and contained high moisture ear corn (HMEC), supplemented with either brewer's dried grains (BDG) or linseed meal (LSM), containing 18% and 46% soluble protein, respectively. To each of these diets, sodium (Na) was either not added or added as NaHCO3 (4% of DM) or NaCl (2.8% of DM). Voluntary intake of organic matter (OM) was significantly (P < 0.05) increased with both NaHCO3 and NaCl supplementation but the response was greater with NaHCO3 than with NaCl. Nitrogen retention tended to be reduced with NaHCO3 supplementation; the reduction was greater with the BDG diet than with the LSM diet. Compared to NaHCO3, NaCl caused a smaller reduction in nitrogen (N) retention when added to the BDG supplemented diet but improved N retention when added to the LSM diet. Blood bicarbonate and base excess (BE) values increased (P < 0.01) with NaHCO3 addition, but the increment in blood bicarbonate and BE tended to be higher with the BDG than the LSM diet. It is concluded that NaHCO3 could impair nitrogen retention by elevating blood bicarbonate in ruminants not suffering acid stress. Key words: Bicarbonate, nitrogen balance, protein solubility, acid-base balance, lambs

scholarly journals Effect of Intensive Fattening of Bulls Fed a High-grain Diet on Selected Health Indicators

2006 ◽  
Vol 75 (2) ◽  
pp. 209-218 ◽  
Author(s):  
E. Štercová ◽  
D. Haas ◽  
A. Krása ◽  
R. Lepková ◽  
J. Šterc
Keyword(s):  
Rumen Fluid ◽  
Health Indicators ◽  
Calcium Content ◽  
Treated Group ◽  
Rumen Fermentation ◽  
Control Group ◽  
Maize Silage ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance

The aim of the study was to investigate the effect of intensive fattening of bulls with a high-grain diet on selected health parameters. Metabolic indicators under study were compared with those in bulls receiving a traditional diet based on maize silage. The trial included 18 Czech pied bulls that were fed a diet containing from 75.0% to 83.6% concentrate on dry matter basis. As a control, 18 Czech pied bulls were used, given total mixed ration based on maize silage. The experiment was started after weaning when the treated group averaged 114 days of age and the control group 115 days of age. Bulls were slaughtered at an average age of 473 days in the treated group and 474 days in the control group. The experiment lasted 359 days. In the fattening period, blood and rumen fluid samples were withdrawn to evaluate rumen fermentation, acid-base balance and selected biochemical indicators. After the slaughter, samples of tuber coxae cancellous tissue were collected for the bone metabolism assessment. Among indicators under study, the rumen fermentation ones were the most affected by feeding the high-grain diet. Bulls fed the high-grain diet showed (P < 0.05) lower rumen fluid pH and a higher total titration activity, a higher (P < 0.01) total level of VFA and propionate proportion, and a lower (P < 0.01) acetate proportion than the control bulls. Counts of infusoria were also lower (P < 0.01). Acid-base balance was not significantly influenced by feeding the high-grain diet. The high-grain diet fed bulls showed increased serum levels of AST and phosphorus, but the differences from the control group were non-significant in most cases. In 1 g bone ash of the samples of tuber coxae cancellous tissue in the treated group calcium content was significantly (P < 0.05) lower than in the control group; no significant differences were observed between other indicators under investigation.

Higher Dietary Acidity is Associated with Lower Bone Mineral Density in Postmenopausal Iranian Women, Independent of Dietary Calcium Intake

2014 ◽  
Vol 84 (3-4) ◽  
pp. 0206-0217 ◽  
Author(s):  
Seyedeh-Elaheh Shariati-Bafghi ◽  
Elaheh Nosrat-Mirshekarlou ◽  
Mohsen Karamati ◽  
Bahram Rashidkhani
Keyword(s):  
Calcium Intake ◽  
Dietary Calcium ◽  
Dietary Calcium Intake ◽  
Dietary Intakes ◽  
Iranian Women ◽  
Acid Base Balance ◽  
Mineral Density ◽  
Acid Base ◽  
Base Balance ◽  
Dietary Acid

Findings of studies on the link between dietary acid-base balance and bone mass are relatively mixed. We examined the association between dietary acid-base balance and bone mineral density (BMD) in a sample of Iranian women, hypothesizing that a higher dietary acidity would be inversely associated with BMD, even when dietary calcium intake is adequate. In this cross-sectional study, lumbar spine and femoral neck BMDs of 151 postmenopausal women aged 50 - 85 years were measured using dual-energy x-ray absorptiometry. Dietary intakes were assessed using a validated food frequency questionnaire. Renal net acid excretion (RNAE), an estimate of acid-base balance, was then calculated indirectly from the diet using the formulae of Remer (based on dietary intakes of protein, phosphorus, potassium, and magnesium; RNAERemer) and Frassetto (based on dietary intakes of protein and potassium; RNAEFrassetto), and was energy adjusted by the residual method. After adjusting for potential confounders, multivariable adjusted means of the lumbar spine BMD of women in the highest tertiles of RNAERemer and RNAEFrassetto were significantly lower than those in the lowest tertiles (for RNAERemer: mean difference -0.084 g/cm2; P=0.007 and for RNAEFrassetto: mean difference - 0.088 g/cm2; P=0.004). Similar results were observed in a subgroup analysis of subjects with dietary calcium intake of >800 mg/day. In conclusion, a higher RNAE (i. e. more dietary acidity), which is associated with greater intake of acid-generating foods and lower intake of alkali-generating foods, may be involved in deteriorating the bone health of postmenopausal Iranian women, even in the context of adequate dietary calcium intake.

The Effect of Long-term Topiramate Treatment on Acid-base Balance in Children with Epilepsy

2016 ◽  
Vol 24 (3) ◽  
pp. 116-121
Author(s):  
김지용 ◽  
남상욱 ◽  
김영미 ◽  
이윤진 ◽  
이훈상 ◽  
...  
Keyword(s):  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance

scholarly journals THE ACID-BASE BALANCE DISTURBANCE OF PREGNANCY

1932 ◽  
Vol 98 (1) ◽  
pp. 253-260 ◽  
Author(s):  
Victor C. Myers ◽  
Edward Muntwyler ◽  
Arthur H. Bill
Keyword(s):  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance
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