The Phosphorus and Calcium Content of the Blood-plasma and Cerebro-spinal Fluid in the Psychoses

1926 ◽  
Vol 72 (296) ◽  
pp. 51-58 ◽  
Author(s):  
H. A. Scholberg ◽  
Edwin Goodall
Keyword(s):  
Blood Plasma ◽  
Medical Research ◽  
Research Laboratory ◽  
Mental Hospital ◽  
Research Council ◽  
Medical Research Council ◽  
Calcium Content ◽  
Spinal Fluid ◽  
Financial Assistance ◽  
The Subject

This work was carried out mainly with financial assistance from the Medical Research Council, to whom the results have been com municated, and to whom our thanks are due.Having regard to the paucity of information on the subject of the phosphorus and calcium-content of blood and cerebro-spinal fluid in the psychoses, and to the consideration that at this mental hospital a research laboratory in chemistry is available, it seemed desirable to investigate these matters.

Clinical Research upon Mentally Ill Subjects Who Cannot Give Informed Consent

1978 ◽  
Vol 133 (4) ◽  
pp. 366-369 ◽  
Author(s):  
I. G. Pryce
Keyword(s):  
Informed Consent ◽  
Clinical Research ◽  
Medical Research ◽  
Mentally Ill ◽  
Research Council ◽  
Medical Research Council ◽  
Research Project ◽  
Direct Benefit ◽  
Proper Understanding ◽  
The Subject

The ProblemOver the last two decades increasing attention has been paid to the rights and safety of the subjects of clinical research. A key safeguard against any abuse has been the requirement to obtain the subject's informed, valid or true consent, which has been defined by the Medical Research Council as ‘consent freely given with proper understanding of the nature and consequences of what is proposed’ (M.R.C., 1962–3). However, it has been recognized by the M.R.C. that it may not be possible to obtain such consent from, among others, some subjects who are mentally ill. Whether or not a research project should be carried out on such subjects should depend, they say, on whether or not ‘there are reasonable grounds for believing that a particular new procedure will contribute to the benefit of that particular patient…’, and further, ‘when true consent cannot be obtained, procedures which are of no direct benefit and which might carry a risk of harm to the subject should not be undertaken’ (M.R.C., 1962–3).

The Effect of Sodium Evipan on the Cerebro-Spinal Fluid Pressure

1936 ◽  
Vol 82 (337) ◽  
pp. 131-135 ◽  
Author(s):  
E. N. Butler
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Medical Research ◽  
Experimental Work ◽  
Research Council ◽  
Medical Research Council ◽  
Fluid Pressure ◽  
Spinal Fluid ◽  
Intravenous Sodium

In view of the increasing use of intravenous sodium evipan as an anaesthetic, any contribution to the knowledge of its pharmacology would seem to be of value. It is known from experimental work and from clinical reports that injection of this drug causes a depression of both respiration and blood-pressure, and that jactitations or twitchings are often present during induction. The report of the Anaesthetics Committee of the Medical Research Council (1) states that there is generally a decrease in the rate of respiration, and that there is a transient fall in systolic blood-pressure of 20–30 mm. Hg. Weese (2) observed a decrease in rate and amplitude of respiration, and a fall of blood-pressure of not more than 20 mm. Hg. Jarman (3) found a fall of 20 mm. or more.

scholarly journals Some Aspects of Meningococcal Virulence: A Report to The Medical Research Council on Work Carried Out at the University of Cambridge Field Laboratories

1923 ◽  
Vol 22 (2) ◽  
pp. 175-207 ◽  
Author(s):  
E. G. D. Murray
Keyword(s):  
Medical Research ◽  
Research Council ◽  
Medical Research Council ◽  
Point Of View ◽  
Common Basis ◽  
University Of Cambridge ◽  
The Subject ◽  
The University

“Virulence” is an ill-defined term and its use frequently gives rise to disputes, which remain unresolved because the disputants have no common basis other than that the term applies to organisms which cause disease. Thus it is imperative that the writer clearly defines the meaning of the term virulence as used in this paper, that the issue may not be confused by the reader approaching the subject from a different point of view.

The Health Legacy of the Emigration: The Irish in Britain and Elsewhere, 1845–1995

1996 ◽  
Vol 6 (1) ◽  
pp. 56-78
Author(s):  
Rory Williams
Keyword(s):  
Medical Research ◽  
High Mortality ◽  
Research Council ◽  
Medical Research Council ◽  
Medical Sociology ◽  
Research Programme ◽  
Historical Background ◽  
Life Chances ◽  
The Subject

Arguing that the life chances of the Irish emigration in different countries of destination are a highly significant topic for sociologists, this article examines aspects of the health of people of Irish descent born in Britain. This is the subject of a research programme in the Medical Sociology Unit in Glasgow, funded by the UK's Medical Research Council. This historical background to this venture lies in the discovery of a health disadvantage among the Irish in Britain, and the establishment of links between the Irish emigration and high mortality in British cities, despite low mortality in Ireland when the migration was at its height. Theoretical accounts which have guided investigation of this issue include the possibility of prolonged effects from early capitalism in Britain, or that of entrenched effects from cultural exclusion, whether derived from competition for jobs and housing, or from political and religious divisions. These varying accounts lead to competing predictions, and the paper concludes by reviewing progress in testing these predictions, and by suggesting implications for research in other countries of destination.

Correlação entre a frequência respiratória e escalas de avaliação de dispneia

2016 ◽  
Vol 13 (6) ◽  
Author(s):  
Ivete Alonso Bredda Saad ◽  
Mariana De Moraes ◽  
Vinicius Minatel ◽  
Bruna Alonso Saad
Keyword(s):  
Medical Research ◽  
Research Council ◽  
Medical Research Council

A avaliação da dispneia tem sido feita por meio de instrumentos como escala de Borg modificada, a escala de cores e a escala do Medical Research Council modificada (mMRC). O objetivo deste estudo foi correlacionar a frequência respiratória com a sensação de dispneia, através das escalas citadas, correlacioná-las entre si e verificar se o grau de alfabetização influenciou na resposta do paciente sobre a sensação de dispneia. Para avaliar o esforço físico utilizou-se o teste de caminhada de seis minutos. Este foi um estudo prospectivo, transversal e analítico-descritivo composto por 124 voluntários com diagnóstico de doença pulmonar. Para comparar as variáveis categóricas entre os grupos foram utilizados os testes Qui-Quadrado e exato de Fisher. Para comparar as variáveis contínuas foi utilizado o teste Kruskal-Wallis e para análise de correlação foi utilizado o coeficiente de correlação de Spearman. A idade média foi de 55,9 (± 13,08 anos), 14% eram analfabetos. Nos tempos de análise houve correlação positiva entre as escalas mMRC e Borg, r = 0,43, r = 0,61 e r = 0,55. Entre as escalas mMRC e Cores, observou-se correlação negativa. Concluiu-se que a frequência respiratória correlacionou-se com as três escalas. O grau de alfabetização não modificou a resposta do paciente em relação à sensação de dispneia.Palavras-chave: dispneia, fisioterapia, avaliação.

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