The Treatment of General Paralysis by Malaria; The Use of Speech Inscriptions for Early Diagnosis

1923 ◽  
Vol 69 (284) ◽  
pp. 77-83 ◽  
Author(s):  
E. W. Scripture

The history of general paralysis records undoubted cases where the disease has for some reason or other seemed for a time actually cured so that the patients could return to work. Although such cases after a short time showed relapse whereby the disease then followed its usual course, this fact is sufficient to indicate the possi bility of stopping the progressive paralysis in some way.

1998 ◽  
Vol 11 (1) ◽  
pp. 396-396
Author(s):  
I. Pustylnik

We study the short-time evolutionary history of the well-known contact binary VW Cep. Our analysis is based partly on the numerous UBV lightcurves obtained at Tartu Observatory, IUE spectra, and samples from the published data. Special attention is given to the effects of asymmetry of the light curves. A higher degree of asymmetry outside the eclipses along with the significant displacements of the brightness maxima in respect to the elongation phase is interpreted as evidence that a considerable portion of the flaring source is concentrated close to the neck connecting the components. We discuss the nature of asymmetry in terms of possible mass exchange and the flare activity and compare the results of our model computations with the record of orbital period variations over the last 60 years.


1888 ◽  
Vol 34 (146) ◽  
pp. 167-176
Author(s):  
G. T. Revington

I think that the foregoing statistics, and those which follow, together with the large number of cases which I quote, and which connect general paralysis with almost every form of neurotic manifestation, will prove conclusively that neurotic inheritance is a striking feature in the causation of general paralysis. I question whether a distinction between “the cerebral and the insane element” in general paralysis can be maintained. If general paralysis is not a degeneration of the mind-tissue, then the pathology of insanity has no existence, and I would say that the subtle influence for evil, which is transmitted from parents, whose brains are deteriorated by neurotic outbursts, or soaked in alcohol, or wrecked by physiological immorality, tends strongly towards such degeneration. If insanity is, as Dr. Savage says, a perversion of the ego, then a general paralytic is the in-sanest of the insane. We know that the children of a melancholic parent, for example, may develop any form of neurosis—in other words, it is not that melancholia or general paralysis, or any other definite disease, is transmitted, but that a certain tendency to deviate from normal development is transmitted. This tendency to deviate is the neurotic diathesis, and the form of its development is determined by collateral circumstances, and a certain series of collateral circumstances determine the development of general paralysis. Perhaps neurotic inheritance may mean in some cases a limited capital of nervous energy, and if this is wasted recklessly the individual breaks down suddenly and pathologically, as we all do slowly and physiologically. I would also point out that considering the number of histories of insanity which owing to ignorance or reticence we, do not receive, and considering that we never receive information as to the existence of the slighter neuroses, it is marvellous that we get so high a percentage as 51. Of the 145 general paralytics with a reliable history, 38 had a family history of insanity, 28 a family history of drink, 8 of both, 43 had a personal history of drink, 8 of a previous attack too remote to be considered, at least, according to our present ideas, as part of the disease, and the vast majority had a history of some physiological irregularity which must be considered as conducive to the creation of an acquired neurosis. We may now pass to some further statistics.


1995 ◽  
Vol 16 (3) ◽  
pp. 117-119
Author(s):  
Randy Cron ◽  
Laurette Ho ◽  
Bradley Bradford

This section of Pediatrics in Review reminds clinicians of those conditions that can present in a misleading fashion and require suspicion for early diagnosis. Emphasis has been placed on conditions in which early diagnosis is important and that the general pediatrician might be expected to encounter, at least once in a while. The reader is encouraged to write possible diagnoses for each case before turning to the discussion, which is on the following page. We invite readers to contribute case presentations and discussions. Case 1 Presentation A previously healthy 6-month-old girl is seen at the office for evaluation of fussiness and infrequent urination. The child has not voided in the past 9 hours despite her usual fluid intake. She is afebrile, with no focus of infection found on careful physical examination. A palpable mass is felt in the suprapubic area. Her external genitalia are normal. Renal and pelvic ultrasonography reveal an echo-free area superior to a normal lower renal ureteral segment on the left side, with a circular echo free area at the lower end of the ureter extending into and taking up about one quarter of the space within a distended bladder. Case 2 Presentation A 4-year-old boy is seen in your office with a 4-day history of sore throat and low-grade fever.


Author(s):  
Megan Rodrigues ◽  
Pratibha Rana ◽  
Gene Lee ◽  
Chaitali Mahajan ◽  
Michael Nyp ◽  
...  

Abstract Objectives Describe clinical characteristics, course, and risk factors for hyper-insulinemic hypoglycemia (HIH) in preterm infants and identify impediments to early diagnosis. Methods Electronic records of infant–mother dyads were used to describe clinical characteristics, lab parameters, and course of HIH. Results All eight patients (gestational ages 26w0d–29w3d) had intrauterine growth restriction (IUGR) due to placental insufficiency, (4/8) were small for gestational age. All maintained normal glucose levels with glucose infusion during the first 48 h six of eight patients had cholestasis despite being on parenteral nutrition for short time (average 17 days). Four of eight patients were treated with diazoxide (average 22 days). Four of eight patients who recovered spontaneously (average 49 days after diagnosis) responded to continuous feeds and hydrocortisone for other clinical indications. Conclusions In IUGR preterms, HIH is asymptomatic, may be prolonged, requiring diazoxide treatment. Transient cholestasis is seen in majority of patients. Euglycemia should be demonstrated on bolus gavage feeds, off glucocorticoids before discontinuing blood glucose monitoring.


1992 ◽  
Vol 13 (11) ◽  
pp. 435-437
Author(s):  
Summer Smith ◽  
John L. Green ◽  
Susan K Lynch ◽  
Mark J. Polak

This section of Pediatrics in Review reminds clinicians of those conditions that can present in a misleading fashion and require suspicion for early diagnosis. Emphasis has been placed on conditions in which early diagnosis is important and that the general pediatrician might be expected to encounter, at least once in a while. The reader is encouraged to write possible diagnoses for each case before turning to the discussion, which is on the following page. We invite readers to contribute case presentations and discussions. Case 1 Presentation A 17-year-old boy is admitted to the hospital for evaluation and management of recently diagnosed diabetes mellitus. His mother expresses concern about his acting-out behavior and about frequent difficulties in drinking from a glass due to tremors. On examination he is found to be 68.5 inches tall, and he has a mild scoliosis. Evaluation of sexual development reveals axillary hair at Tanner stage III, pubic hair at stage V, penile length of 8 cm, left testicular volume of 3.0 x 1.8 cm, and an undescended right testicle. No breast tissue is palpable. Case 2 Presentation A 16-year-old girl is seen at your office with a history of prolonged fatigue and weakness. She has missed school frequently over the past 4 to 5 months, having had many vague complaints of "no energy," headaches, sore throats, aching knees, and the feeling that she will almost "pass out" if she does gymnastics or physical exertion of any kind.


Anthropos ◽  
2021 ◽  
Vol 116 (2) ◽  
pp. 367-378
Author(s):  
Carlos Nogueira

In this article I address the problem of the definition, manifestations, characteristics, and causes of catastrophic evil (one that leads hundreds or thousands of people to exclusion, suffering and death in a short time). To this end, I start from a set of George Steiner’s theses on the nature of evil that José Saramago’s thought and literary discourse confirm and support with an eloquence and depth that is rare in both the history of ideas and and in universal literature.


1893 ◽  
Vol 39 (165) ◽  
pp. 217-224
Author(s):  
M. J. Nolan

At the present time, when our fin de siècle knowledge of “general paralysis” enables us to recognize under that generic term many types of the disorder, and when the relation between it and syphilis continues a rather vexed question, little apology is needed for introducing to notice the following cases. They illustrate unmistakably some of the instances in which syphilis is solely responsible for what. Is termed by Dr. Savage” A process of degeneration which ultimately produces the ruin we recognize as general paralysis.”∗ Whatever may be hereafter formulated from the present evolutionary crisis in the history of the disorder there can be but little doubt that syphilis will be one of its most intimate and important relations. The story of its methods is briefly sketched in the following two short life-histories—in one asserting itself in the offspring of its victims by right of impure heredity, in the other carrying death direct into the vital centres by the force of its malignant virus.


2021 ◽  
Vol 76 (1) ◽  
pp. 85-101
Author(s):  
Luca Dei Cas ◽  
Maria Luisa Pastore ◽  
Andrea Pavan ◽  
Nicola Petrella

Abstract. In areas located near large rock cliffs, risk reduction by early warning monitoring systems highligts potentiality but also critical issues and limits. The paper examines two rock slope failures that occurred in a short time from each other near inhabited areas in the Italian Alps. The viscous behavior of the rock mass was reconstructed through data processing from ground-based Synthetic Aperture Radar Interferometry (InSAR), and elaboration of acceleration and speed curves. Landslides types and underlying complexity associated with rock detachment mechanisms suggest the identification of precautionary alarm thresholds for collapse forecasting. The analysis of financial outlay, both for mitigation works and for monitoring activities, highlight the adequacy and the opportunity to combine passive systems, like embankments or rockfall drapery meshes, with a reliable monitoring network for early warning.


2013 ◽  
pp. 779-788
Author(s):  
Anatolij Turilov

The article is devoted to filling gaps in the history of Byzantine ecclesiastical hierarchy mid - late XIV-XV centuries. It consists of two parts. In the first one the author succeeds in using little known or forgotten Slavic written sources set the name of the Ohrid Archbishop of late XIV - early XV centuries, set the name of the Ohrid Archbishop of late XIV - early XV centuries, and a suggestion about the name of another Chapter of this Department first half of the XV century. The second part is devoted to the unknown until now Metropolitan of Heraclea Thracian a short time took this Department in 1410?s and carrying out probably important diplomatic missions.


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