The Clinical Value and Significance of Leucocytosis in Mental Disease

1914 ◽  
Vol 60 (248) ◽  
pp. 56-72 ◽  
Author(s):  
D. J. Jackson

The problem of leucocytosis has been the subject of much discussion in recent years. Amongst the earlier workers on the subject Virchow stands prominent, and he first gave the name of leucocytosis to a temporary increase in the number of leucocytes in the blood, this occurring both in physiological and pathological conditions. During the past twenty years special attention has been paid to this phenomenon, bringing to light some very important information. Amongst later workers Metchnikoff has done more to enlighten us as to the problem than any other worker. To briefly recapitulate his doctrine. The leucocytes protect the organism against harmful germs by catching them up in their pseudopods, by investing them, and thus robbing them of the possibility of exerting their deleterious action externally. The termination of an infective process would therefore depend alone on whether leucocytes possessing this function are present in the blood in sufficient numbers to overcome the invasion of the germs. The doctrine of Metchnikoff has been modified and also extended by other workers, notably Denys, Löwy, and Richter, who have proved that the value of the leucocytes does not depend on their pseudopods, but that their chemical products yield the strongest protection to the organism. The leucocytes are able by means of the bactericidal or antitoxic substances which they give off to paralyse the toxins produced by the bacteria, and in this way render the microbes harmless by depriving them of the weapons of attack, even if they cannot destroy them.

1913 ◽  
Vol 59 (247) ◽  
pp. 596-605 ◽  
Author(s):  
E. Barton White

The occurrence of micro-organisms in the urine is well known to be associated with a variety of pathological conditions, among which mental diseases have been included. A definite connection between urinary bacteria and insanity, however, does not seem to have been made out, the subject being even more obscure than the relation of the intestinal flora to mental disease, which has been much more frequently investigated.


1911 ◽  
Vol 57 (236) ◽  
pp. 55-63
Author(s):  
T. E. K. Stansfield
Keyword(s):  
The Past ◽  

The subject of heredity in relation to the mental evolution of the race and to mental disease is of such supreme importance that I plead no excuse for making it the subject of my paper. It is a subject which has not in the past received that amount of attention from us as alienists which its momentous-ness demands. But the work of Galton, the revivified monumental experiments of Mendel, and the investigations of the school of biometricians, headed by Karl Pearson, have latterly given a great impetus to this line of study.


1863 ◽  
Vol 9 (46) ◽  
pp. 173-196 ◽  
Author(s):  
W. H. O. Sankey

During the past few years there have been published, both in this country and on the continent, several comprehensive treatises on the subject of insanity, as well as new editions of older works. In England there has been issued a new edition of the volume by Drs. Bucknill and Tuke, a volume on ‘Obscure Mental Disease,’ &c., by Dr. Forbes Winslow. In Germany, a new edition of the work of Griesinger, ‘Die Pathologie und Therapie der Psychischen Krankheiten;’ and in 1859, ‘Lehrbuch der Psychiatre,’ by Neumann, and ‘Allgemeine Pathologie der Seele,’ by Wachsmuth, each of which enjoys an extensive reputation. In France, a ‘Traité Elémentaire et Pratique des Maladies Mentales,’ par Dr. Dagonet, of Strasbourg; ‘Traité Pratique des Maladies Mentales,’ par Dr. L. V. Marcé, of Paris. In 1860, ‘Traité des Maladies Mentales,’ par Dr. B. A. Morel, of Rouen; in 1859, ‘Traité des Maladies Inflammatoires du Cerveau,’ par le Dr. L. F. Calmeil. It is the aim of the present article to examine into views entertained by the authors of the above works on the subject of melancholia, and to compare them with those contained in the writings of older writers, as well as with opinions to be found scattered in the periodical literature of insanity. It is true, that the aim of the different writers named was different while writing their works. One class of them have had for their object to produce digested handbooks, others original and scientific treatises. While the one avoid discussion on disputed points, the others make such discussion an important part of their works.


MedAlliance ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. 87-95

Cardiovascular diseases are the main cause of death in developed and developing countries, so the issues of their earliest diagnosis are the subject of many scientific studies and discussions. Over the past decade, there have been many significant discoveries in the field of preven-tive cardiology. The target values of the majority of risk factors that directly contribute to the development of cardiac diseases and form an unfavorable prognosis for the patient are determined. Meanwhile, questions about methods of early diagnosis of pathological conditions and strategies for influencing risk factors in different groups of patients remain open.


1997 ◽  
Vol 36 (4I) ◽  
pp. 321-331
Author(s):  
Sarfraz Khan Qureshi

It is an honour for me as President of the Pakistan Society of Development Economists to welcome you to the 13th Annual General Meeting and Conference of the Society. I consider it a great privilege to do so as this Meeting coincides with the Golden Jubilee celebrations of the state of Pakistan, a state which emerged on the map of the postwar world as a result of the Muslim freedom movement in the Indian Subcontinent. Fifty years to the date, we have been jubilant about it, and both as citizens of Pakistan and professionals in the social sciences we have also been thoughtful about it. We are trying to see what development has meant in Pakistan in the past half century. As there are so many dimensions that the subject has now come to have since its rather simplistic beginnings, we thought the Golden Jubilee of Pakistan to be an appropriate occasion for such stock-taking.


Author(s):  
Daiva Milinkevičiūtė

The Age of Enlightenment is defined as the period when the universal ideas of progress, deism, humanism, naturalism and others were materialized and became a golden age for freemasons. It is wrong to assume that old and conservative Christian ideas were rejected. Conversely, freemasons put them into new general shapes and expressed them with the help of symbols in their daily routine. Symbols of freemasons had close ties with the past and gave them, on the one hand, a visible instrument, such as rituals and ideas to sense the transcendental, and on the other, intense gnostic aspirations. Freemasons put in a great amount of effort to improve themselves and to create their identity with the help of myths and symbols. It traces its origins to the biblical builders of King Solomon’s Temple, the posterity of the Templar Knights, and associations of the medieval craft guilds, which were also symbolical and became their link not only to each other but also to the secular world. In this work we analysed codified masonic symbols used in their rituals. The subject of our research is the universal Masonic idea and its aspects through the symbols in the daily life of the freemasons in Vilnius. Thanks to freemasons’ signets, we could find continuity, reception, and transformation of universal masonic ideas in the Lithuanian freemasonry and national characteristics of lodges. Taking everything into account, our article shows how the universal idea of freemasonry spread among Lithuanian freemasonry, and which forms and meanings it incorporated in its symbols. The objective of this research is to find a universal Masonic idea throughout their visual and oral symbols and see its impact on the daily life of the masons in Vilnius. Keywords: Freemasonry, Bible, lodge, symbols, rituals, freemasons’ signets.


No other talent process has been the subject of such great debate and emotion as performance management (PM). For decades, different strategies have been tried to improve PM processes, yielding an endless cycle of reform to capture the next “flavor-of-the-day” PM trend. The past 5 years, however, have brought novel thinking that is different from past trends. Companies are reducing their formal processes, driving performance-based cultures, and embedding effective PM behavior into daily work rather than relying on annual reviews to drive these. Through case studies provided from leading organizations, this book illustrates the range of PM processes that companies are using today. These show a shift away from adopting someone else’s best practice; instead, companies are designing bespoke PM processes that fit their specific strategy, climate, and needs. Leading PM thought leaders offer their views about the state of PM today, what we have learned and where we need to focus future efforts, including provocative new research that shows what matters most in driving high performance. This book is a call to action for talent management professionals to go beyond traditional best practice and provide thought leadership in designing PM processes and systems that will enhance both individual and organizational performance.


Urban Science ◽  
2020 ◽  
Vol 4 (4) ◽  
pp. 70
Author(s):  
Till Koglin ◽  
Lucas Glasare

This paper evaluates the history and cycling accessibility of Nova, a shopping centre established in Lund, Sweden, in 2002. The current situation was also analysed through observation and a literature review. Moreover, the study conducted a closer analysis of the history and role of the municipality based on further literature study and interviews with officials. The conclusion of the analysis indicates poor and unsafe bikeways caused by conflicts of interest between politicians, officials, landowners and the general public. It also depicts a situation in which the municipality’s master plan has been ignored, and, in contrast to the local goals, cycling accessibility at Nova has seen no significant improvement since the shopping centre was first established. The reasons for this, arguably, are a relatively low budget for bikeway improvements in the municipality, as well as a situation in which decision-makers have stopped approaching the subject, as a result of the long and often boisterous conflicts it has created in the past. Lastly, it must be noted that it is easy to regard the whole process of Nova, from its establishment to the current situation, as being symptomatic of the power structures between drivers and cyclists that still affect decision-makers at all levels.


Universe ◽  
2021 ◽  
Vol 7 (6) ◽  
pp. 169
Author(s):  
Cristina Lazzeroni ◽  
Sandra Malvezzi ◽  
Andrea Quadri

The rapid changes in science and technology witnessed in recent decades have significantly contributed to the arousal of the awareness by decision-makers and the public as a whole of the need to strengthen the connection between outreach activities of universities and research institutes and the activities of educational institutions, with a central role played by schools. While the relevance of the problem is nowadays unquestioned, no unique and fully satisfactory solution has been identified. In the present paper we would like to contribute to the discussion on the subject by reporting on an ongoing project aimed to teach Particle Physics in primary schools. We will start from the past and currently planned activities in this project in order to establish a broader framework to describe the conditions for the fruitful interplay between researchers and teachers. We will also emphasize some aspects related to the dissemination of outreach materials by research institutions, in order to promote the access and distribution of scientific information in a way suited to the different age of the target students.


2020 ◽  
Author(s):  
Léon E Dijkman

Abstract Germany is one of few jurisdictions with a bifurcated patent system, under which infringement and validity of a patent are established in separate proceedings. Because validity proceedings normally take longer to conclude, it can occur that remedies for infringement are imposed before a decision on the patent’s validity is available. This phenomenon is colloquially known as the ‘injunction gap’ and has been the subject of increasing criticism over the past years. In this article, I examine the injunction gap from the perspective of the right to a fair trial enshrined in Art. 6 of the European Convention on Human Rights. I find that the case law of the European Court of Human Rights interpreting this provision supports criticism of the injunction gap, because imposing infringement remedies with potentially far-reaching consequences before the validity of a patent has been established by a court of law arguably violates defendants’ right to be heard. Such reliance on the patent office’s grant decision is no longer warranted in the light of contemporary invalidation rates. I conclude that the proliferation of the injunction gap should be curbed by an approach to a stay of proceedings which is in line with the test for stays as formulated by Germany’s Federal Supreme Court. Under this test, courts should stay infringement proceedings until the Federal Patent Court or the EPO’s Board of Appeal have ruled on the validity of a patent whenever it is more likely than not that it will be invalidated.


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