Clinical Notes on Haemorrhages in General Paralysis

1886 ◽  
Vol 31 (136) ◽  
pp. 504-507
Author(s):  
Geo. H. Savage

In so-called nervous disorders it is common to find changes occur in other of the bodily systems than the nervous. The pathology of nervous disease should be looked upon as a general pathology, and it is certain that we cannot look to the one system alone for causes of all the nervous disorders without greatly misunderstanding the whole subject. The more exact we become in limiting the causes, the more liable are we to error. We are all prepared to consider general paralysis of the insane as essentially a disease of the nervous system, a disease in which nearly every part of the nervous system may suffer sooner or later. But beside the essentially nervous symptoms which occur in the disease, we are constantly struck by the regular series of nutritional changes which occur in general paralysis, and this is so much the case that we are quite prepared to recognise as general paralysis a disorder in which any mental symptoms have been present, but have after a brief period of acuteness been followed by a state of fatness and weak-mindedness which again has been followed by a period of wasting and further mental weakness. We have here nervous symptoms related very directly with nutritional changes.

1859 ◽  
Vol 5 (28) ◽  
pp. 286-289
Author(s):  
Reicharz ◽  
Edward Palmer

la describing the relative sizes of unequal pupils in the diseases of the central organ of the nervous system (as in incomplete general paralysis) most observers make special mention of the dilated pupil, and, under precisely similar essential conditions, we more frequently find one pupil characterised as being larger than the other, than the converse. Were there no prejudice at the bottom of this custom, there might be nothing to advance against it; but I believe that the views on which it is founded, are, more or less, conjectural. It is apparently assumed, in the first place, that inequality of the pupils is always caused by lesion of one iris only; that dilatation of the pupil is more truly and more frequently a morbid condition, than contraction; and, finally, that dilatation is always dependent on relaxation, resulting from paralysis. The iris, with the dilatated pupil is, thus, more often pointed out as being affected, and that with paralysis, than the one in which the pupil is contracted; and we find, moreover, that it is quite usual to adduce, not perhaps, mere inequality, but dilatation of the pupils generally, as an absolute sign and example of paralysis of single muscles.


Author(s):  
В. А. Сальников ◽  
Е. М. Ревенко

В статье рассматривается соотношение возрастных и индивидуально-типологических особенностей в развитии двигательных способностей в системе физического воспитания и спортивной деятельности. Отмечается, что на рубеже 60 - 80-х гг. прошлого века получен обширный материал относительно развития двигательных способностей, где возраст выступал в качестве интегрального показателя. В исследованиях последующего периода явно обозначилось, что возрастной критерий не позволяет в полной мере раскрыть закономерности развития двигательных способностей, а возраст как таковой не может отражать какого бы то ни было стандартного процесса развития. Утверждается, что возрастные особенности наиболее полно могут быть представлены в контексте целостного процесса индивидуального развития человека. Результаты исследования показали, что в процессе взросления развитие двигательных способностей связано со свойствами нервной системы, при этом выявленные связи существенно различаются в различные возрастные периоды. Также существенно различаются связи, с одной стороны, исходных уровней проявлений двигательных способностей, с другой, - темпов их прироста с типологическими свойствами нервной системы в отдельно взятых возрастных периодах. Наличие устойчивых взаимосвязей уровней проявлений и темпов прироста двигательных способностей со свойствами нервной системы свидетельствует об индивидуальных траекториях развития двигательных проявлений в онтогенезе. Знание последних позволит индивидуализировать образовательный и тренировочный процессы. Динамика развития двигательных способностей определяется совокупностью типологических особенностей проявления свойств нервной системы - типологическим комплексом. The article deals with the correlation of age and individual typological features in the development of motor abilities in the system of physical education and sports activities. It is noted that at the turn of the 60 - 80s of the last century, extensive material was obtained on the development of motor abilities, where age was an integral indicator. In studies of the subsequent period, it was clearly indicated that the age criterion does not allow to fully reveal the laws of development of motor abilities, and age as such cannot reflect any standard development process. It is argued that age-related features can be most fully represented in the context of a holistic process of individual human development. The results of the study showed that in the process of growing up, the development of motor abilities is associated with the properties of the nervous system, while the revealed connections differ significantly in different age periods. There are also significant differences in the relationship, on the one hand, of the initial levels of motor abilities, and, on the other hand, the rate of their growth with the typological properties of the nervous system in individual age periods. The presence of stable relationships between the levels of manifestations and the rate of growth of motor abilities with the properties of the nervous system indicates individual trajectories of development of motor manifestations in ontogenesis. Knowledge of the latter will allow you to individualize the educational and training processes. Dynamics of development of motor abilities is determined by a set of typological features of the manifestation of the properties of the nervous system - a typological complex.


2018 ◽  
Vol 23 (1) ◽  
pp. 10-13
Author(s):  
James B. Talmage ◽  
Jay Blaisdell

Abstract Injuries that affect the central nervous system (CNS) can be catastrophic because they involve the brain or spinal cord, and determining the underlying clinical cause of impairment is essential in using the AMA Guides to the Evaluation of Permanent Impairment (AMA Guides), in part because the AMA Guides addresses neurological impairment in several chapters. Unlike the musculoskeletal chapters, Chapter 13, The Central and Peripheral Nervous System, does not use grades, grade modifiers, and a net adjustment formula; rather the chapter uses an approach that is similar to that in prior editions of the AMA Guides. The following steps can be used to perform a CNS rating: 1) evaluate all four major categories of cerebral impairment, and choose the one that is most severe; 2) rate the single most severe cerebral impairment of the four major categories; 3) rate all other impairments that are due to neurogenic problems; and 4) combine the rating of the single most severe category of cerebral impairment with the ratings of all other impairments. Because some neurological dysfunctions are rated elsewhere in the AMA Guides, Sixth Edition, the evaluator may consult Table 13-1 to verify the appropriate chapter to use.


Planta Medica ◽  
2015 ◽  
Vol 81 (11) ◽  
Author(s):  
J Zhang ◽  
Z Yang ◽  
Y Zhu ◽  
L Wang ◽  
J Wang ◽  
...  

1985 ◽  
Vol 53 (01) ◽  
pp. 122-125 ◽  
Author(s):  
B Åstedt ◽  
Ingegerd Lecander ◽  
T Brodin ◽  
A Lundblad ◽  
Karin Löw

SummaryA monoclonal antibody of IgG2a-type was obtained against a specific fast acting plasminogen activator inhibitor found in placenta. The placental inhibitor was purified by affinity chromatography using the monoclonal antibody and additionally in a FPLC-system. A strong complex formation was found between the inhibitor and urokinase and also with the two-chain form of plasminogen activator of the tissue-type. A weaker complex was found between the placental inhibitor and the one- chain form of the tissue-type activator.


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