The familial aggregation of common psychiatric and substance use disorders in the National Comorbidity Survey: A family history study

1997 ◽  
Vol 170 (6) ◽  
pp. 541-548 ◽  
Author(s):  
Kenneth S. Kendler ◽  
Christopher G. Davis ◽  
Ronald C. Kessler
Keyword(s):  
Substance Use ◽  
Psychiatric Disorders ◽  
Substance Use Disorders ◽  
Antisocial Personality Disorder ◽  
Familial Aggregation ◽  
Generalised Anxiety Disorder ◽  
Familial Transmission ◽  
National Comorbidity Survey ◽  
Externalising Disorders ◽  
History Of

BackgroundMost family studies of psychiatric disorders examine one syndrome at a time, and identify probands in clinical rather than epidemiological settings.MethodIn the National Comorbidity Survey, 5877 respondents were asked about the history of five psychiatric disorders in their parents: major depression (MD), generalised anxiety disorder (GAD), antisocial personality disorder (ASP), alcohol abuse/dependence (AAD) and drug abuse/dependence (DAD).ResultsSignificant familial aggregation was seen for all disorders. Controlling for other disorders produced only modest reductions in the odds ratios for MD. GAD and AAD and larger reductions for ASP and DAD. The familial transmission of these disorders can be explained by underlying vulnerabilities to internalising and to externalising disorders transmitted across generations with moderate fidelity.ConclusionsFamilial aggregation of common psychiatric and substance use disorders is substantial in epidemiologic samples. The examined environmental adversities account for little of the observed parent-offspring transmission of these conditions.

Neurobiology of Comorbid Substance Use Disorders and Psychiatric Disorders

2017 ◽  
Vol 28 (1) ◽  
pp. 11-26 ◽  
Author(s):  
Yatan Pal Singh Balhara ◽  
Pooja Patnaik Kuppili ◽  
Rishab Gupta
Keyword(s):  
Substance Use ◽  
Psychiatric Disorders ◽  
Substance Use Disorders

scholarly journals Substance Use Disorders in Men Presenting to a Psychosexual Clinic

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Ravi Philip Rajkumar
Keyword(s):  
Substance Use ◽  
Family History ◽  
Sexual Dysfunction ◽  
Substance Use Disorders ◽  
Substance Dependence ◽  
Causal Relation ◽  
Alcohol Use Disorders ◽  
Community Based ◽  
History Of ◽  
A Current

Introduction. Substance use disorders (SUDs) are commonly associated with a variety of psychiatric disorders. Community-based studies have found a significant association between SUDs and sexual dysfunction in men, with a possible causal relation in the case of nicotine. Methods. The case records of 105 men presenting to a clinic for patients with psychosexual disorders were reviewed. Men with and without comorbid SUDs were compared in terms of demographic, clinical, and familial variables. Results. 25 of the 105 men (23.8%) had a lifetime diagnosis of SUD, and 19 (18.1%) had a current SUD. The commonest substances involved were nicotine (n = 21, 20%) and alcohol (n = 9, 9.5%). Men with comorbid SUDs were more likely to report a family history of substance dependence, particularly alcoholism. Single men with SUDs were more likely to have a comorbid mood disorder. Conclusion. SUDs, particularly nicotine and alcohol use disorders, are common comorbidities in patients with psychosexual disorders. Identifying and treating these disorders in this population are important aspects of management.

Comorbidity of Severe Psychiatric Disorders and Substance Use Disorders Among Women in Jail

2003 ◽  
Vol 160 (5) ◽  
pp. 1007-1010 ◽  
Author(s):  
Karen M. Abram ◽  
Linda A. Teplin ◽  
Gary M. McClelland
Keyword(s):  
Substance Use ◽  
Psychiatric Disorders ◽  
Substance Use Disorders

scholarly journals Seasonal Allergies and Psychiatric Disorders in the United States

2018 ◽  
Vol 15 (9) ◽  
pp. 1965 ◽  
Author(s):  
Hans Oh ◽  
Ai Koyanagi ◽  
Jordan DeVylder ◽  
Andrew Stickley
Keyword(s):  
Mental Health ◽  
United States ◽  
Eating Disorders ◽  
Substance Use ◽  
Psychiatric Disorders ◽  
Mood Disorders ◽  
Substance Use Disorders ◽  
Mental Health Problems ◽  
The United States ◽  
Seasonal Allergies

Seasonal allergies have been associated with mental health problems, though the evidence is still emergent, particularly in the United States. We analyzed data from the National Comorbidity Survey Replication and the National Latino and Asian American Survey (years 2001–2003). Multivariable logistic regression models were used to examine the relations between lifetime allergies and lifetime psychiatric disorders (each disorder in a separate model), adjusting for socio-demographic variables (including region of residence) and tobacco use. Analyses were also stratified to test for effect modification by race and sex. A history of seasonal allergies was associated with greater odds of mood disorders, anxiety disorders, and eating disorders, but not alcohol or substance use disorders, after adjusting for socio-demographic characteristics and tobacco use. The associations between seasonal allergies and mood disorders, substance use disorders, and alcohol use disorders were particularly strong for Latino Americans. The association between seasonal allergies and eating disorders was stronger for men than women. Seasonal allergies are a risk factor for psychiatric disorders. Individuals complaining of seasonal allergies should be screened for early signs of mental health problems and referred to specialized services accordingly.

Substance Use Disorders

2018 ◽  
Author(s):  
F Gerard Moeller
Keyword(s):  
Substance Use ◽  
Substance Use Disorders ◽  
Channel Blockers ◽  
Medical Problems ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Life Threatening ◽  
History Of ◽  
Abused Drugs ◽  
Nmda Receptor Channel

There is a consistent body of evidence showing that substance abuse and dependence can worsen preexisting medical conditions, can temporarily mimic medical and psychiatric disorders, and can themselves cause medical problems, including life-threatening overdose. Substance use disorders are common in young and middle-aged persons: the lifetime prevalence of these syndromes, including alcoholism, is over 20% for men and about 15% for women. This chapter discusses dependence, abuse, substance use disorder, and substance-induced disorders involving depressants, stimulants, opioids, cannabinoids, hallucinogens, N-methyl-D-aspartate (NMDA) receptor channel blockers, and inhalants. Epidemiology, etiology, pathophysiology, diagnosis (including clinical assessment and laboratory tests), and treatment are reviewed. Treatment of intoxication, overdose, withdrawal, and rehabilitation is discussed. A figure illustrates the neurocircuitry of addiction. Tables describe the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) diagnostic criteria for abuse and dependence; frequently misused drugs; neural effects of commonly abused drugs; the natural history of drug dependence; conditions affecting the outcome of urinary drug tests; and pharmacologic options for treatment of drug overdose. This chapter contains 1 figure , 6 tables and 112 references

Mental Illness and Substance Use Disorders Among Homeless Veterans

2018 ◽  
pp. 35-60
Author(s):  
Sonya Gabrielian ◽  
Ashton M. Gores ◽  
Lillian Gelberg ◽  
Jack Tsai
Keyword(s):  
Mental Illness ◽  
Substance Use ◽  
Psychiatric Disorders ◽  
Substance Use Disorders ◽  
Supported Housing ◽  
United States Armed Forces ◽  
Homeless Veterans ◽  
Veteran Status ◽  
Epidemiology Data ◽  
Housing Outcomes

Mental illness and substance use disorders (SUDs) are strong risk factors for homelessness, regardless of Veteran status. This chapter describes the interplay between mental illness, SUDs, the co-occurrence of these disorders (CoD), and homelessness among Veterans; the authors consider military-specific experiences (e.g., combat) and factors associated with homelessness for both Veteran and non-Veteran adults (e.g., childhood adversity). They present epidemiology data on mental illness and SUDs among homeless Veterans, considering specific diagnoses (e.g., post-traumatic stress disorder) and experiences (e.g., military sexual trauma) that are highly prevalent within or unique to persons who served in the United States Armed Forces. In addition, the authors present qualitative and quantitative data on pathways to homelessness for Veterans with mental illness, SUDs, and/or CoD, considering distinct pathways seen in special populations (e.g., women Veterans, who have high rates of trauma, and the newest cohort of Veterans who served in Iraq or Afghanistan). Last, the authors discuss supported housing outcomes for homeless Veterans with psychiatric disorders and SUDs. They discuss the utility of these programs for homeless Veterans with mental health problems and explore the influence of psychiatric disorders and SUDs among Veterans with poor supported housing outcomes.

Young Adult Outcome of Attention Deficit Hyperactivity Disorder

2016 ◽  
Author(s):  
Mai Uchida ◽  
Joseph Biederman
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Substance Use ◽  
Psychiatric Disorders ◽  
Substance Use Disorders ◽  
Attention Deficit ◽  
Massachusetts General Hospital ◽  
Emotional Dysregulation ◽  
Neural Basis ◽  
Hyperactivity Disorder ◽  
Wide Range

The Massachusetts General Hospital (MGH) Longitudinal Studies of Attention Deficit Hyperactivity Disorder (ADHD) evaluated and followed a large sample of both boys and girls with ADHD and controls without ADHD, along with their families, ascertained from psychiatric and pediatric sources. These studies documented that ADHD in both sexes is associated with high levels of persistence onto adulthood; high levels of familiality with ADHD and other psychiatric disorders; a wide range of comorbid psychiatric and cognitive disorders including mood, anxiety, and substance use disorders; learning disabilities with reading and math; executive function deficits; emotional dysregulation and autistic traits; as well as educational, social, and occupational dysfunctions. The MGH studies also suggested that stimulant treatment significantly decreased the risk of developing comorbid psychiatric disorders, substance use disorders, and impaired functional outcomes. The studies also documented the neural basis of the persistence of ADHD using resting-state functional magnetic resonance imaging (fMRI).

Sign in / Sign up

Export Citation Format

Share Document