Speech and Language in First Onset Psychosis Differences Between People with Schizophrenia, Mania, and Controls

1996 ◽  
Vol 168 (3) ◽  
pp. 337-343 ◽  
Author(s):  
Philip Thomas ◽  
Gabby Kearney ◽  
Elizabeth Napier ◽  
Elin Ellis ◽  
Ivan Leudar ◽  
...  
Keyword(s):  
Working Memory ◽  
Psychiatric Patients ◽  
Evolutionary Model ◽  
Low Complexity ◽  
Syntactic Analysis ◽  
Group Differences ◽  
Psychotic Symptoms ◽  
Significant Group ◽  
Memory And Attention ◽  
First Onset

BackgroundSeveral studies have revealed linguistic differences between diagnostic groups. This study investigates the extent to which these differences are accounted for by factors such as chronicity, or disturbances in cognition associated with acute psychosis.MethodTranscripts of interviews with patients suffering from RDC schizophrenia (n=38), mania (n=11) and controls (n=16) were examined using the Brief Syntactic Analysis (BSA). Patients were within two years of first onset of psychotic symptoms, and received tests of working memory and attention.ResultsThe speech of patients with schizophrenia was syntactically less complex than that of controls. Patients with schizophrenia and mania made more errors than controls. These differences were, to some extent, related to group differences in social class, working memory and attention, although significant group differences in language persisted after the effects of covariates were removed.ConclusionsThe study confirms the existence of differences in the speech of psychiatric patients. Low complexity appears to be a particular feature of speech in schizophrenia, even in the earliest stages of the condition. The importance of this finding is discussed in relation to two recent theories of schizophrenia: Crow's evolutionary model, and Friths neuro-psychological model.

Comparison of Auditory, Language, Memory, and Attention Abilities in Children With and Without Listening Difficulties

2020 ◽  
Vol 29 (4) ◽  
pp. 710-727
Author(s):  
Beula M. Magimairaj ◽  
Naveen K. Nagaraj ◽  
Alexander V. Sergeev ◽  
Natalie J. Benafield
Keyword(s):  
Auditory Processing ◽  
Short Term Memory ◽  
Group Differences ◽  
Long Term Memory ◽  
Short Term ◽  
Significant Group ◽  
Term Memory ◽  
Memory And Attention ◽  
Speed And Accuracy

Objectives School-age children with and without parent-reported listening difficulties (LiD) were compared on auditory processing, language, memory, and attention abilities. The objective was to extend what is known so far in the literature about children with LiD by using multiple measures and selective novel measures across the above areas. Design Twenty-six children who were reported by their parents as having LiD and 26 age-matched typically developing children completed clinical tests of auditory processing and multiple measures of language, attention, and memory. All children had normal-range pure-tone hearing thresholds bilaterally. Group differences were examined. Results In addition to significantly poorer speech-perception-in-noise scores, children with LiD had reduced speed and accuracy of word retrieval from long-term memory, poorer short-term memory, sentence recall, and inferencing ability. Statistically significant group differences were of moderate effect size; however, standard test scores of children with LiD were not clinically poor. No statistically significant group differences were observed in attention, working memory capacity, vocabulary, and nonverbal IQ. Conclusions Mild signal-to-noise ratio loss, as reflected by the group mean of children with LiD, supported the children's functional listening problems. In addition, children's relative weakness in select areas of language performance, short-term memory, and long-term memory lexical retrieval speed and accuracy added to previous research on evidence-based areas that need to be evaluated in children with LiD who almost always have heterogenous profiles. Importantly, the functional difficulties faced by children with LiD in relation to their test results indicated, to some extent, that commonly used assessments may not be adequately capturing the children's listening challenges. Supplemental Material https://doi.org/10.23641/asha.12808607

Responsivity of Psychiatric Patients to Verbal Conditioning: “Success” and “Failure” Conditions and Pattern of Reinforced Trials

1963 ◽  
Vol 12 (2) ◽  
pp. 423-426 ◽  
Author(s):  
Robert L. Weiss ◽  
Leonard Krasner ◽  
Leonard Ullmann
Keyword(s):  
College Students ◽  
Psychiatric Patients ◽  
Group Differences ◽  
Social Reinforcement ◽  
Verbal Conditioning ◽  
Significant Group ◽  
Emotional Words ◽  
Evaluation Of Performance ◽  
Failure Conditions

A sample of 64 psychiatric patients was used to study responsiveness to minimal social reinforcement by means of operant verbal conditioning procedures. As in previous work with college students the effects of two types of situational variation were studied: pattern of reinforced trials and examiner's evaluation of performance. Ss told TAT-like stories and on selected trials the use of emotional words was reinforced. Highly significant conditioning was found, indicating that psychiatric patients are responsive to minimal social reinforcement. Significant group differences were not found, however, for either the success-failure dimension of examiner evaluation of performance, or for reinforced vs extinction trials. The results for patients agree with those reported earlier for students only insofar as the initial conditioning is concerned. In general, patients show initial responsiveness to examiner reinforcement, but they are not readily influenced by situational variations occurring later in the session.

scholarly journals Baseline working memory activation deficits in dimensional anxious depression as detected by magnetoencephalography

2015 ◽  
Vol 27 (3) ◽  
pp. 143-152 ◽  
Author(s):  
Dawn F. Ionescu ◽  
Allison C. Nugent ◽  
David A. Luckenbaugh ◽  
Mark J. Niciu ◽  
Erica M. Richards ◽  
...  
Keyword(s):  
Working Memory ◽  
Memory Task ◽  
Task Demands ◽  
Group Differences ◽  
Brain Response ◽  
Beta Band ◽  
Significant Group ◽  
Band Frequency ◽  
Anxious Depression ◽  
Preliminary Study

ObjectiveAnxiety often co-occurs with major depressive disorder (MDD). This preliminary study sought to ascertain the extent to which anxious depression drives group neurobiological differences between patients with MDD and healthy volunteers (HVs).MethodsMagnetoencephalography beta-band frequency was used to compare differences in brain response during the N-back working memory task between 30 medication-free patients with treatment-resistant MDD (anxious depression=18; nonanxious depression=12) and 28 HVs.ResultsCompared to HVs, patients with anxious depression had significantly reduced desynchronisation (less activation) in the left precuneus, right cuneus, and left insula extending into the inferior and middle frontal cortex during the 2-back condition compared with the 1-back condition of the N-back working memory task – indicating less activation of these neural networks in patients with anxious depression during the condition with the highest level of task demands. No other significant group differences were found during the working memory conditions.ConclusionThis preliminary study suggests that a subset of patients – those with anxious depression – may be driving observed group differences between patients with MDD and HVs. Further neurobiological studies and replication experiments are necessary to determine the extent to which this subgroup has preferentially influenced our understanding of the underlying neurobiology of depression.

Spatial and Nonspatial Working Memory and Visual Search

2011 ◽  
Vol 108 (3) ◽  
pp. 893-907
Author(s):  
Junichi Takahashi ◽  
Takao Hatakeyama
Keyword(s):  
Working Memory ◽  
Individual Differences ◽  
Visual Search ◽  
Test Scores ◽  
Spatial Working Memory ◽  
Conjunction Search ◽  
Group Differences ◽  
Search Rate ◽  
Significant Group ◽  
The Individual

It has been indicated that visual search is interfered with in spatial working memory (WM), although not in nonspatial WM. In this study, the effects on visual search of individual differences in spatial and nonspatial WM were examined. Two visual search conditions were used: a conjunction search condition comprising two features (color and shape) and a disjunction condition comprising only one feature (color or shape). 96 participants (42 men, 54 women, M age = 20.9 yr., SD = 3.5) participated in this study. The participants were divided into high and low WM groups based on their spatial and nonspatial WM test scores. As a result, statistically significant group differences in the conjunction search rate were observed in spatial WM but not in nonspatial WM. These results suggest there is a relationship between visual search and the individual spatial WM ability, but this does not hold for nonspatial WM.

Interrelations of Psychiatric Diagnosis, Psychological Profile and Ethnic Background

1978 ◽  
Vol 43 (1) ◽  
pp. 55-61 ◽  
Author(s):  
Barry A. Schneider ◽  
Ellen L. Schneider ◽  
Anne S. Hardesty ◽  
Eugene I. Burdock
Keyword(s):  
Analysis Of Variance ◽  
Psychiatric Diagnosis ◽  
Social Influences ◽  
Psychiatric Patients ◽  
Severity Of Illness ◽  
Group Differences ◽  
Psychological Profile ◽  
Chi Square ◽  
Significant Group

200 psychiatric patients, who had been classified as black, white, or Hispanic at the admitting office, were divided into broad diagnostic groups according to the psychiatrist's diagnosis at termination. Chi-square analyses comparing ethnicity and diagnosis yielded no significant differences. A psychologist administered the Structured Clinical Interview in the admitting office prior to determination of precipitating events and assignment of diagnosis. When scores were compared by analysis of variance, no significant group differences were found on over-all severity of illness, but three of the 10 subareas showed significant differences. The results may reflect cultural and social influences.

Behavioral and emotional differences between children of divorce and children from intact families: Clinical significance and mediating processes *This study is part of a dissertation () supported from the German research community.

2002 ◽  
Vol 61 (1) ◽  
pp. 5-14 ◽  
Author(s):  
Andreas Schick
Keyword(s):  
Self Esteem ◽  
Research Community ◽  
Children Of Divorce ◽  
Group Differences ◽  
Significant Group ◽  
Intact Families ◽  
Divorce Adjustment ◽  
Theoretical Assumptions ◽  
German Research ◽  
Clinically Significant

The following study is based on a sample of 241 9-13-year-old children (66 children from divorced parents, 175 children from non divorced parents). They were examined for differences regarding anxiety, self-esteem, different areas of competence, and degree of behavior problems. With a focus on the children’s experiences, the clinically significant differences were examined. Clinically significant differences, revealing more negative outcomes for the children of divorce, were only found for social anxiety and unstable performance. The frequency of clinical significant differences was independent of the length of time the parents had been separated. The perceived destructiveness of conflict between the parents one of four facets of interparental conflict in this study functioned as a central mediator of the statistically significant group differences. The children’s perception of the father’s social support was a less reliable indicator of variance. Further studies should try to make underlying theoretical assumptions about the effects of divorce more explicit, to distinguish clearly between mediating variables, and to investigate them with respect to specific divorce adjustment indicators.

scholarly journals Effects of aging on emotion recognition from dynamic multimodal expressions and vocalizations

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Diana S. Cortes ◽  
Christina Tornberg ◽  
Tanja Bänziger ◽  
Hillary Anger Elfenbein ◽  
Håkan Fischer ◽  
...  
Keyword(s):  
Older Adults ◽  
Emotion Recognition ◽  
Positive Emotions ◽  
Negative Emotions ◽  
Group Differences ◽  
Significant Group ◽  
Positivity Effect ◽  
Video Recordings ◽  
Age Related ◽  
Effects Of Aging

AbstractAge-related differences in emotion recognition have predominantly been investigated using static pictures of facial expressions, and positive emotions beyond happiness have rarely been included. The current study instead used dynamic facial and vocal stimuli, and included a wider than usual range of positive emotions. In Task 1, younger and older adults were tested for their abilities to recognize 12 emotions from brief video recordings presented in visual, auditory, and multimodal blocks. Task 2 assessed recognition of 18 emotions conveyed by non-linguistic vocalizations (e.g., laughter, sobs, and sighs). Results from both tasks showed that younger adults had significantly higher overall recognition rates than older adults. In Task 1, significant group differences (younger > older) were only observed for the auditory block (across all emotions), and for expressions of anger, irritation, and relief (across all presentation blocks). In Task 2, significant group differences were observed for 6 out of 9 positive, and 8 out of 9 negative emotions. Overall, results indicate that recognition of both positive and negative emotions show age-related differences. This suggests that the age-related positivity effect in emotion recognition may become less evident when dynamic emotional stimuli are used and happiness is not the only positive emotion under study.

Standardised ginseng extract G115® potentiates the antidepressant-like properties of fluoxetine in the forced swim test

2021 ◽  
pp. 1-7
Author(s):  
Dylan J. Terstege ◽  
Debra S. MacDonald ◽  
R. Andrew Tasker
Keyword(s):  
Prefrontal Cortex ◽  
Forced Swim Test ◽  
Ginseng Root ◽  
Group Differences ◽  
Post Mortem ◽  
Ginseng Extract ◽  
Significant Group ◽  
Swim Test ◽  
Forced Swim ◽  
Plus Maze

Abstract Objective: Ginsenosides, biologically active components of the root of Panax ginseng, have been reported to have therapeutic benefits in a number of disease states including psychiatric conditions such as major depressive disorder. Our objective was to determine if a standardised commercial ginseng extract, G115®, could reduce the signs of behavioural despair commonly observed in animal models of depression either alone or in combination with the selective serotonin reuptake inhibitor (SSRI) fluoxetine. Methods: Male Sprague-Dawley (SD) rats (N = 51) were divided into four groups: vehicle control, G115® ginseng root extract, fluoxetine and fluoxetine plus G115®. Rats were trained to voluntarily consume treatments twice daily for 14 days and were then tested in an open field (OF), elevated plus maze (EPM) and forced swim test (FST). Post-mortem hippocampal and prefrontal cortex tissue was analysed for expression of brain-derived neurotrophic factor (BDNF) and tropomyosin receptor kinase B (TrkB) by western blot. Results: One-way Analysis of Variance revealed no significant group differences in the OF or plus-maze performance on any variable examined. In the FST, fluoxetine significantly reduced immobility time and increased latency to immobility. The effects of fluoxetine were further significantly potentiated by co-administration of G115®. Post-mortem tissue analysis revealed significant group differences in BDNF expression in the left hippocampus and left prefrontal cortex without any accompanying changes in TrkB expression. Conclusions: We conclude that oral G115® significantly potentiates the antidepressant-like effect of fluoxetine in the FST in the absence of potentially confounding effects on locomotion and anxiety.

scholarly journals Behavioural Measures of Infant Activity but Not Attention Associate with Later Preschool ADHD Traits

2021 ◽  
Vol 11 (5) ◽  
pp. 524
Author(s):  
Amy Goodwin ◽  
Alexandra Hendry ◽  
Luke Mason ◽  
Tessel Bazelmans ◽  
Jannath Begum Ali ◽  
...  
Keyword(s):  
Family History ◽  
Child Behaviour ◽  
Activity Level ◽  
Group Differences ◽  
Early Interventions ◽  
Significant Group ◽  
Assessment Protocol ◽  
History Of ◽  
Observer Ratings ◽  
Infant Attention

Mapping infant neurocognitive differences that precede later ADHD-related behaviours is critical for designing early interventions. In this study, we investigated (1) group differences in a battery of measures assessing aspects of attention and activity level in infants with and without a family history of ADHD or related conditions (ASD), and (2) longitudinal associations between the infant measures and preschool ADHD traits at 3 years. Participants (N = 151) were infants with or without an elevated likelihood for ADHD (due to a family history of ADHD and/or ASD). A multi-method assessment protocol was used to assess infant attention and activity level at 10 months of age that included behavioural, cognitive, physiological and neural measures. Preschool ADHD traits were measured at 3 years of age using the Child Behaviour Checklist (CBCL) and the Child Behaviour Questionnaire (CBQ). Across a broad range of measures, we found no significant group differences in attention or activity level at 10 months between infants with and without a family history of ADHD or ASD. However, parent and observer ratings of infant activity level at 10 months were positively associated with later preschool ADHD traits at 3 years. Observable behavioural differences in activity level (but not attention) may be apparent from infancy in children who later develop elevated preschool ADHD traits.

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