Long-Term Mortality in Anorexia Nervosa

1992 ◽  
Vol 161 (1) ◽  
pp. 104-107 ◽  
Author(s):  
Arthur H. Crisp ◽  
John S. Callender ◽  
Christine Halek ◽  
L. K. George Hsu
Keyword(s):  
Anorexia Nervosa ◽  
Medical Treatment ◽  
Causes Of Death ◽  
Early Mortality ◽  
Psychotherapeutic Treatment ◽  
Late Mortality ◽  
Long Term Mortality

Two cohorts of anorexia nervosa patients were followed up for a mean of 20 years. All except 4% of each cohort was traced. The crude mortalities were: St George's, 4%; Aberdeen, 13%. The SMRs were: St George's, 136; Aberdeen, 471. If the untraced were assumed to be dead, crude mortalities were 7.6% and 15.9% respectively, and SMRs were 276 and 592 respectively. Causes of death were complications of the illness and suicide. Medical treatment may reduce early mortality, while comprehensive medical and psychotherapeutic treatment may reduce late mortality.

scholarly journals Long-Term Mortality after Histoplasma Infection in People with HIV

2021 ◽  
Vol 7 (5) ◽  
pp. 369
Author(s):  
Joseph Cherabie ◽  
Patrick Mazi ◽  
Adriana M. Rauseo ◽  
Chapelle Ayres ◽  
Lindsey Larson ◽  
...  
Keyword(s):  
Statistical Significance ◽  
Modern Art ◽  
Private Insurance ◽  
Early Mortality ◽  
Late Mortality ◽  
Significant Difference ◽  
Common Opportunistic Infection ◽  
Long Term Survivors ◽  
Long Term Mortality

Histoplasmosis is a common opportunistic infection in people with HIV (PWH); however, no study has looked at factors associated with the long-term mortality of histoplasmosis in PWH. We conducted a single-center retrospective study on the long-term mortality of PWH diagnosed with histoplasmosis between 2002 and 2017. Patients were categorized into three groups based on length of survival after diagnosis: early mortality (death < 90 days), late mortality (death ≥ 90 days), and long-term survivors. Patients diagnosed during or after 2008 were considered part of the modern antiretroviral therapy (ART) era. Insurance type (private vs. public) was a surrogate indicator of socioeconomic status. Out of 54 PWH infected with histoplasmosis, overall mortality was 37%; 14.8% early mortality and 22.2% late mortality. There was no statistically significant difference in survival based on the availability of modern ART (p = 0.60). Insurance status reached statistical significance with 38% of survivors having private insurance versus only 8% having private insurance in the late mortality group (p = 0.05). High mortality persists despite the advent of modern ART, implicating a contribution from social determinants of health, such as private insurance. Larger studies are needed to elucidate the role of these factors in the mortality of PWH.

scholarly journals Long-term mortality in young patients with spontaneous intracerebral haemorrhage: Predictors and causes of death

2021 ◽  
Vol 6 (2) ◽  
pp. 185-193
Author(s):  
Jamie I Verhoeven ◽  
Marco Pasi ◽  
Barbara Casolla ◽  
Hilde Hénon ◽  
Frank-Erik de Leeuw ◽  
...  
Keyword(s):  
Mortality Risk ◽  
Intracerebral Haemorrhage ◽  
Causes Of Death ◽  
Cox Regression ◽  
Young Patients ◽  
University Hospital ◽  
Standardized Mortality Ratio ◽  
Excessive Alcohol Consumption ◽  
Long Term Mortality

Introduction Intracerebral haemorrhage (ICH) in young adults is rare but has devastating consequences. We investigated long-term mortality rates, causes of death and predictors of long-term mortality in young spontaneous ICH survivors. Patients and methods We included consecutive patients aged 18–55 years from the Prognosis of Intracerebral Haemorrhage cohort (PITCH), a prospective observational cohort of patients admitted to Lille University Hospital (2004–2009), who survived at least 30 days after spontaneous ICH. We studied long-term mortality with Kaplan-Meier analyses, collected causes of death, performed uni-/multivariable Cox-regression analyses for the association of baseline characteristics with long-term mortality. Results Of 560 patients enrolled in the PITCH, 75 patients (75% men) met our inclusion criteria (median age 50 years, interquartile range [IQR] 44–53 years). During a median follow-up of 8.2 years (IQR 5.0–10.1), 26 patients died (35%), with a standardized mortality ratio of 13.0 (95% confidence interval [95% CI] 8.5–18.0) compared to peers from the general population. Causes of death were vascular in 7 (27%) patients, non-vascular in 13 (50%) and unknown in 6 (23%). Global cerebral atrophy (hazard ratio [HR] 3.0, 95% CI 1.1–8.6), modified Rankin Score >2 before ICH (HR 3.4, 95% CI 1.0–11.0), and excessive alcohol consumption (HR 3.3, 95% CI 1.1–10.2) were independently associated with long-term mortality. Discussion We found a 13-fold higher mortality risk for young ICH survivors compared to the general French population. Predictors of long-term mortality were pre-existing conditions, not ICH-characteristics. Conclusion Young ICH survivors remain at increased mortality risk of vascular and non-vascular death for years after ICH.

Long-term mortality and causes of death among patients with mild traumatic brain injury: a 5-year multicenter study

Brain Injury ◽  
2020 ◽  
Vol 34 (4) ◽  
pp. 556-566 ◽  
Author(s):  
Erica Sercy ◽  
Alessandro Orlando ◽  
Matthew Carrick ◽  
Mark Lieser ◽  
Robert Madayag ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Multicenter Study ◽  
Causes Of Death ◽  
Long Term Mortality

Short- and long-term mortality and causes of death after reconstruction of cancers of the head and neck with free flaps

2019 ◽  
Vol 57 (1) ◽  
pp. 21-28 ◽  
Author(s):  
S. Lahtinen ◽  
P. Koivunen ◽  
T. Ala-Kokko ◽  
O. Kaarela ◽  
P. Ohtonen ◽  
...  
Keyword(s):  
Head And Neck ◽  
Causes Of Death ◽  
Free Flaps ◽  
Short And Long Term ◽  
Long Term Mortality

scholarly journals Short- and long-term mortality and causes of death in HIV/tuberculosis patients in Europe

2013 ◽  
Vol 43 (1) ◽  
pp. 166-177 ◽  
Author(s):  
D. N. Podlekareva ◽  
A. M. Panteleev ◽  
D. Grint ◽  
F. A. Post ◽  
J. M. Miro ◽  
...  
Keyword(s):  
Causes Of Death ◽  
Tuberculosis Patients ◽  
Short And Long Term ◽  
Long Term Mortality

Predicting factors for early and long-term mortality after thoracotomy in patients with primary lung cancer.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. e18562-e18562
Author(s):  
Cynthia van Arkel ◽  
Daphne Dumoulin ◽  
Bart van Straten ◽  
Joost ter Woorst ◽  
Saskia Houterman ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Regression Analysis ◽  
Primary Lung Cancer ◽  
Early Mortality ◽  
Predicting Factors ◽  
Time Period ◽  
History Of ◽  
Long Term Mortality

e18562 Background: To determine factors predicting early and long term mortality in patients who underwent a thoracotomy because of primary lung cancer. Methods: Data of patients who underwent a thoracotomy in the Catharina Hospital Eindhoven between 1 January 1995 and 1 January 2011 have been collected retrospectively from the medical files. Early mortality was defined as mortality <30 days after surgery. Last date of follow up was 1 January 2013. Patients were divided in three periods according to date of surgery (1: 1995-1999, 2: 2000-2004 and 3: 2005-2010). Predicting factors for early mortality were assessed with uni- and multivariate logistic regression analysis. For long term mortality and survival predicting factors were assessed using the Cox proportional hazards model and Kaplan-Meier survival curves. Results: In total 501 patients underwent a thoracotomy due to primary lung cancer. Overall 30 day mortality was 5.8% (n=29). Early mortality was 3.0% for lobectomy (n=289), 0.2% for bilobectomy (n=29) and 11% for pneumonectomy (n=109). Multivariate analysis showed that age over 70 (p=0.002), pneumonectomy (p=0.008) and a pre-operative VO2max of <15 ml/kg/min (p=0.02) were significant predictors of early mortality. With respect to long term survival, 308 (62%) patients had died at the end of the follow-up period. Median survival time was 44 months, with an overall 5- and 10- year survival of 45% and 27% respectively. The 5- and 10-year survival for stage I, II and III-IV was 61% and 37%; 46% and 30%;16% and 6.6%, respectively (p<0.0001, log rank test). Finally Cox regression analysis showed that stage (stage I (HR 0.30; 95% CI 0.22-0.42), stage II (HR 0.38; 95% CI 0.26-0.57) compared to stage III-IV, FEV1% ≤70% (HR 1.57; 95% CI 1.61-2.11), a history of cerebrovascular disease (CVD) (HR 1.97; 95% CI 1.20-3.23) and surgery in an earlier time period (1 (HR 1.50; 95% CI 1.04-2.17); 2 (HR 1.46; 95% CI 1.05-2.02) compared to 3) were significant predictors of long term mortality. Conclusions: In this cohort age, pneumonectomy and pre-operative VO2max are significant predictors of early mortality. Significant predictors of long term mortality are disease stage, FEV1%, a history of CVD and surgery in an earlier time period.

scholarly journals Late Mortality and Causes of Death among Long-Term Survivors after Allogeneic Stem Cell Transplantation

2016 ◽  
Vol 22 (9) ◽  
pp. 1702-1709 ◽  
Author(s):  
Yoshiko Atsuta ◽  
Akihiro Hirakawa ◽  
Hideki Nakasone ◽  
Saiko Kurosawa ◽  
Kumi Oshima ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Allogeneic Stem Cell Transplantation ◽  
Causes Of Death ◽  
Late Mortality ◽  
Long Term Survivors

Seventeen-Year Mortality following the Acute Coronary Syndrome: Gender-Specific Baseline Variables and Impact on Outcome

Cardiology ◽  
2019 ◽  
Vol 143 (1-2) ◽  
pp. 22-31
Author(s):  
Annica Ravn-Fischer ◽  
Elisabeth Perers ◽  
Thomas Karlsson ◽  
Kenneth Caidahl ◽  
Marianne Hartford
Keyword(s):  
Acute Coronary Syndrome ◽  
Cardiogenic Shock ◽  
Cox Regression ◽  
Late Mortality ◽  
Killip Class ◽  
Coronary Syndrome ◽  
Gender Specific ◽  
Long Term Mortality

Background: Gender differences in outcome and its predictors in patients with acute coronary syndrome (ACS) continue to be debated. Objectives: To assess long-term mortality and explore its association with the baseline variables in women and men. Methods: We followed 2,176 consecutive patients (665 women and 1,511 men) with ACS admitted to a single hospital and still alive after 30 days for a median of 16 years 8 months. Results: At the end of the follow-up, 415 (62.4%) women and 849 (56.2%) men had died (unadjusted hazard ratio [HR] for women/men 1.18 (95% confidence interval [CI], 1.05–1.33, p =0.005). After adjustment for age, the HR was reversed to 0.88 (95% CI, 0.78–1.00, p =0.04). Additional adjustment for potential confounders yielded a HR of 0.86 (95% CI, 0.76–0.98, p = 0.02). Using multivariable Cox regression, previous heart failure, previous or new-onset atrial fibrillation, and psychotropic drugs at discharge were significantly associated with increased long-term mortality in men only. Known hypertension, elevated creatinine, and inhospital Killip class >1/cardiogenic shock were significantly associated with mortality only in women. For late mortality, hypertension and inhospital Killip class >1/cardiogenic shock interacted significantly with gender. Conclusion: For patients with ACS surviving the first 30 days, late mortality was lower in women than in men after adjusting for age. The effects of several baseline characteristics on late outcome differed between women and men. Gender-specific strategies for long-term follow-up of ACS patients should be considered.

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