Anorexia Nervosa: Outcome and Prognostic Factors after 20 Years

1991 ◽  
Vol 158 (4) ◽  
pp. 495-502 ◽  
Author(s):  
R. H. Ratnasuriya ◽  
I. Eisler ◽  
G. I. Szmukler ◽  
G. F. M. Russell

Forty-one patients with anorexia nervosa, admitted to the Maudsley Hospital between 1959 and 1966, were followed up after a mean of 20 years. An assessment of general outcome (based on the Morgan-Russell scales) yielded three outcome categories: ‘good’ (n = 12), ‘intermediate’ (n = 13) and ‘poor’ (n = 15). Six patients (15%) had died from causes related to anorexia nervosa; at least 15% had developed bulimia nervosa. There was a general consistency between the follow-up at 20 years and that previously conducted five years after admission, although with a few individual patients there were serious prognostic errors at the earlier follow-up. A poorer outcome was associated with a later age of onset, a history of neurotic and personality disturbances, disturbed relationships in the family and a longer duration of illness.

PEDIATRICS ◽  
1982 ◽  
Vol 70 (4) ◽  
pp. 525-525
Author(s):  
Robert J. Haggerty

Anorexia nervosa is a serious psychosomatic disorder which most typically begins between 16 and 18 years of age. Clinicians have often held that early onset (eg, ages 11 to 15) is associated with a better outcome. This paper reviews the long-term outcome studies on anorexia nervosa and concludes that this contention is not supported by available data. The methodologies of seven outcome studies that focus on an early onset population are critiqued, and it is concluded that two methodologies are strong. Because of the increasing prevalence of anorexia nervosa, this once rare disorder can now be more easily investigated, and consequently better follow-up studies, which examine potential prognostic factors including age of onset, should be forthcoming.


1990 ◽  
Vol 31 (2) ◽  
pp. 171-175 ◽  
Author(s):  
James E. Mitchell ◽  
Richard L. Pyle ◽  
Elke D. Eckert ◽  
Dorothy Hatsukami ◽  
Elizabeth Soll

2019 ◽  
Vol 28 (1) ◽  
pp. 34-45
Author(s):  
Robertas Strumila ◽  
Benedicte Nobile ◽  
Laurent Maimoun ◽  
Isabelle Jaussent ◽  
Maude Seneque ◽  
...  

Diagnostics ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 1089
Author(s):  
Soochul Park ◽  
Myeongjee Lee

A total of 472 epilepsy patients with a 4-year remission period were divided into 10-year age groups according to age of onset. The relapse patterns during at least 3 years of follow-up were classified as early relapse (ER), late relapse (LR), and seizure-free (SF). The remission probability and multiplicity of prognostic factors were evaluated using univariate and multivariate multinomial logistic analyses. The weighted risk score based on odd ratios (ORs) was used for comparisons of the relative risk of relapse between groups. The group with onset in their 20s had the lowest remission probability among the groups. The risks of relapse in the LR patients and the relative weighted risk score of ER patients in the group with onset in their 20s were 3.11 and 19.44, respectively, which was the highest risk among the age groups. Patients without remission within 1 year had the highest relapse risk, with an OR of 7.18 in ER patients. The OR of relapse in patients with >10 generalized tonic–clonic (GTC) seizures was the second most important prognostic factor in LR patients. The distinct risk and corresponding prognostic factors in LR and ER patients reflected inherent differences between these relapse patterns.


1986 ◽  
Vol 149 (6) ◽  
pp. 780-782 ◽  
Author(s):  
P. Sturmey ◽  
P. D. Slade

Anorexia nervosa is frequently associated with neurotic traits and symptoms. The symptomatology and history of a housebound 20-year-old woman with anorexia nervosa and dysmorphophobia are described. The role of the family In maintaining the problems, use of external cues to control behaviour, overvalued somatic ideas and the definition of dysmorphophobia are discussed.


2007 ◽  
Vol 38 (5) ◽  
pp. 737-746 ◽  
Author(s):  
C. González-Blanch ◽  
B. Crespo-Facorro ◽  
M. Álvarez-Jiménez ◽  
J. M. Rodríguez-Sánchez ◽  
J. M. Pelayo-Terán ◽  
...  

BackgroundPredicting cognitive deficits in early psychosis may well be crucial to identify those individuals most in need of receiving intensive intervention. As yet, however, the identification of potential pretreatment predictors for cognitive performance has been hampered by inconsistent findings across studies. We aimed to examine the associations of functional and clinical pretreatment variables with cognitive functioning after a first psychotic episode.MethodOne hundred and thirty-one patients experiencing first-episode psychosis were assessed for psychopathology, pre-morbid functioning, duration of illness, age of onset, and family history of psychosis and neurocognitive functioning. Multiple regression analyses were conducted for six basic cognitive dimensions known to be affected in this population: verbal learning, verbal memory, verbal comprehensive abilities, executive functioning, motor dexterity and sustained attention.ResultsPre-morbid functioning was the main predictor for five out of the six basic cognitive domains. Pre-morbid social adjustment difficulties were associated with worse performance in executive functioning, motor dexterity and sustained attention. Academic functioning was associated with verbal comprehension, and verbal learning and memory. Gender, age of onset, duration of untreated psychosis, and family history of psychosis had no or limited value as predictors of neurocognitive outcome.ConclusionsPoor pre-morbid functioning was related to a worse performance in the six basic cognitive dimensions evaluated; however, this accounted for only a small amount of the explained variance. Cognitive impairment is a prominent feature in patients with early psychosis regardless of favorable prognostic features such as short duration of illness, female gender, later age of onset, and non-family history of psychosis.


Author(s):  
Luca Errichiello ◽  
Davide Iodice ◽  
Dario Bruzzese ◽  
Marco Gherghi ◽  
Ignazio Senatore

2017 ◽  
Vol 86 (6) ◽  
pp. 376-378 ◽  
Author(s):  
Giovanni Castellini ◽  
Lorenzo Lelli ◽  
Elisa Corsi ◽  
Beatrice Campone ◽  
Eleonora Ciampi ◽  
...  

1995 ◽  
Vol 25 (5) ◽  
pp. 1019-1025 ◽  
Author(s):  
I. F. Dancyger ◽  
P. E. Garfinkel

SYNOPSISA variety of sociocultural, familial and individual features associated with the eating disorders were examined in subjects with full syndrome (FS) and partial syndrome (PS) eating disorders and in normal high school students. The EAT-26 was administered to 995 high school students. This was followed by individual interviews with those who scored in the symptomatic range. Fifty-one students with PS eating disorders, 57 students without eating disorders (normal controls) and 30 hospital patients with FS, anorexia nervosa or bulimia nervosa were compared on subscales of the Eating Disorder Inventory, the Diagnostic Survey for Eating Disorders and the Beck Depression Inventory. The three groups displayed statistically significant differences on dimensions of EDI subscales Ineffectiveness and Interoceptive Awareness and also with respect to depression, history of being overweight and past history of emotional problems, as well as having mothers with medical illnesses. On these characteristics, the FS subjects displayed higher levels than the PS subjects, who in turn were higher than the NC subjects. The PS subjects displayed elevations on Body Dissatisfaction (EDI subscale), past medical illnesses, and mother's over-concern with eating and weight. These data support a continuum model of the eating disorders, but a continuum of multiple associated features rather than of dieting.


Sign in / Sign up

Export Citation Format

Share Document