Factors Related to Self-reporting of the Pre-menstrual Syndrome

1990 ◽  
Vol 157 (2) ◽  
pp. 249-260 ◽  
Author(s):  
Pamela Warner ◽  
John Bancroft

Menstrual health questionnaires were completed by a self-selected sample of the readership of a woman's magazine (n = 5457). Sixty-one per cent of subjects described themselves as suffering from pre-menstrual syndrome (PMS) and this was largely corroborated by ratings of symptoms pre-menstrually, menstrually and post-menstrually for the most recent cycle. Mood symptoms were more strongly implicated than physical ones. Self-report of PMS was found to be modestly associated with aspects of parity and oral contraceptive use, but strongly and positively related to the duration of ‘natural’ menstrual cycles (i.e. uninterrupted by pregnancy or steroidal contraception) and to psychosocial stress. There were interactions among psychosocial factors and between psychosocial load and duration of natural cycles.

2007 ◽  
Vol 53 (10) ◽  
pp. 1808-1813 ◽  
Author(s):  
Sylvain Clauser ◽  
Séverine Peyrard ◽  
Pascale Gaussem ◽  
Malvina Crespin ◽  
Joseph Emmerich ◽  
...  

Abstract Background: Gas6 is a vitamin K–dependent antiapoptotic protein that has been implicated in cardiovascular pathophysiology. We report the development and validation of an ELISA for Gas6, and the variation of plasma Gas6 with hormonal status in a study designed to evaluate the effect of oral contraception on plasma markers. Methods: After validation of the main stages of the ELISA assay, we measured plasma Gas6 concentrations in 94 male and 88 female healthy volunteers ages 18 to 38 years. Forty-five of the women then received an oral contraceptive, which contained ethinylestradiol and levonorgestrel, for 3 months before a new measurement was performed at the same time point in their menstrual cycles. Results: Interassay imprecision was 5.8%–11.8%, and the detection limit was 5.9 μg/L. Mean Gas6 plasma concentrations were significantly lower in men (52.0 μg/L) than in women not receiving oral contraceptives (63.8 μg/L, P <0.001). In the women who received oral contraceptives, Gas6 concentrations decreased after 3 months of therapy from 63.6 μg/L to 51.9 μg/L (P <0.001). Conclusions: We have developed a simple and reproducible ELISA assay for measuring plasma Gas6 concentrations, which vary with sex and are decreased by oral contraceptive use. These results suggest regulation of plasma Gas6 concentrations by sex hormones. Future clinical studies may require participants to be stratified by sex.


2015 ◽  
Vol 09 (02) ◽  
pp. 171-175
Author(s):  
Karina Helga Leal Turcio ◽  
Alício Rosalino Garcia ◽  
Paulo Renato Junqueira Zuim ◽  
Amália Moreno ◽  
Marcelo Coelho Goiato ◽  
...  

ABSTRACT Objective: The aim of this study was to evaluate the influence of oral contraceptive use on the silent period (SP) of anterior temporal and masseter muscles during the menstrual cycle. Materials and Methods: Totally, 28 women on reproductive age were selected including 15 nonusers of any hormone and 13 contraceptive users. All patients were dentate without muscular temporomandibular disorders. Electromyography (SP test) of the anterior temporal and masseter muscles was conducted every week during three consecutive menstrual cycles at 1st day of menstruation (P1), 7th day (P2), 14th day (P3) and 21st day (P4). Results: The SP values in the anterior temporal and masseter muscles were measured at both sides. The SP values of the right side (13.49 ms) at P2 were significantly different compared to the left side (12.28 ms). However, there was no significant difference on the interactions among the three factors. Conclusion: It can be concluded that the SP values in healthy women in reproductive age may not be influenced by the menstrual cycle with similar results for both muscles.


Author(s):  
Thomas J. Anderson ◽  
Sharon Battersby

SynopsisThe modifications that occur to breast tissue as a consequence of different physiological states of the female are considered with particular respect to oestrogen. Various tissue responses can be noted and the implications of modulation in cell proliferation, as a consequence of menstrual cycles, pregnancy, oophorectomy and oral contraceptive use, are considered. Assessment of oestrogen receptor by immuno-cytochemistry confirms the involvement of the steroid as a cell stimulant. Evidence from a variety of sources indicates the role in normal breast epithelium is more permissive than deterministic.


1978 ◽  
Vol 39 (03) ◽  
pp. 743-750 ◽  
Author(s):  
Anne M Hedlin ◽  
Susan Milojevic ◽  
Andrew Korey

SummaryThe effect of Demulen (ethinyl estradiol 0.05 mg and ethynodiol diacetate 1 mg) and exercise on the level of plasminogen activators was studied in 25 women (12 controls and 13 contraceptive users).Plasma plasminogen activator level was increased by the use of the oral contraceptive and further increased by exercise. Urine plasminogen activator level was unchanged by the use of Demulen but, in both groups of subjects, was decreased by exercise.


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