The Significance of Stupor in the Long-Term Outcome of Chronic Schizophrenia

1989 ◽  
Vol 155 (3) ◽  
pp. 352-355 ◽  
Author(s):  
J. C. Rigby ◽  
S. M. Wood ◽  
R. H. S. Mindham
Keyword(s):  
Psychiatric Hospital ◽  
Mental State ◽  
Chronic Schizophrenia ◽  
Favourable Outcome ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Chronic Schizophrenic ◽  
Schizophrenic Patients ◽  
Similar Sample

The admission records of 271 long-stay chronic schizophrenic patients, resident in a large psychiatric hospital, were examined in order to identify those who had presented in stupor at the onset of their illness. Twelve patients were found (ten men and two women). When compared, in terms of current mental state and behaviour, with a similar sample of schizophrenics in whom stupor had been absent, significant differences between the two groups were detected, with those presenting in stupor demonstrating a less favourable outcome.

Geriatric Mental State-AGECAT: Prevalence, Incidence and Long-Term Outcome of Dementia and Organic Disorders in the Liverpool Study of Continuing Health in the Community

1992 ◽  
Vol 11 (1) ◽  
pp. 84-87 ◽  
Author(s):  
J.R.M. Copeland ◽  
M.E. Dewey ◽  
I.A. Davidson ◽  
P.A. Saunders ◽  
A. Scott
Keyword(s):  
Mental State ◽  
Term Outcome ◽  
Long Term Outcome

Prediction of outcome in neurotic disorder: a 5-year prospective study

1998 ◽  
Vol 28 (5) ◽  
pp. 1149-1157 ◽  
Author(s):  
H. SEIVEWRIGHT ◽  
P. TYRER ◽  
T. JOHNSON
Keyword(s):  
Initial Response ◽  
Favourable Outcome ◽  
Dysthymic Disorder ◽  
Response To Treatment ◽  
Behaviour Therapy ◽  
Neurotic Disorder ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Predicting Outcome

Background. There have been no previous studies of the outcome of different neurotic disorders in which a prospective group with original randomization to treatment have been followed up over a long period. Such studies are important in identifying the factors associated with good and poor outcome.Methods. A 5-year follow-up assessment was made of a cohort of 210 psychiatric out-patients seen in general practice psychiatric clinics with a DSM-III diagnosis of generalized anxiety disorder (71), panic disorder (74) or dysthymic disorder (65) and randomized to drug treatment, cognitive and behaviour therapy, and self-help. A total of 182 of the patients (87%) were assessed after 5 years by examination of hospital and GP records using a standardized procedure and outcome determined with a four-point outcome scale.Results. One hundred and seven (60%) of the patients had a favourable outcome but the remainder continued to be handicapped either intermittently or continuously throughout the 5-year period. Analysis of the value of initial data in predicting outcome using polychotomous step-wise logistic regression revealed that five variables were significant predictors of poor prognosis: older age; recurrent episodes; the presence of personality disorder at entry; general neurotic syndrome at entry; and symptom severity after 10 weeks. The initial DSM diagnosis and original treatment given, together with ten other variables, were of no predictive value.Conclusions. The long-term outcome of neurotic disorder is better predicted by age, personality and recency of onset than by other clinical variables with the exception of initial response to treatment.

scholarly journals Long-term outcome after tricuspid valvectomy in a neonate with Candida endocarditis: a case report

2019 ◽  
Vol 29 (4) ◽  
pp. 528-530
Author(s):  
Ellen S. I. Vanhie ◽  
Ad J. J. C. Bogers ◽  
Willem A. Helbing
Keyword(s):  
Case Report ◽  
Surgical Intervention ◽  
Pulmonary Regurgitation ◽  
Favourable Outcome ◽  
Early Infancy ◽  
Term Outcome ◽  
Long Term Outcome

AbstractTricuspid valvectomy is a rare surgical intervention, and knowledge regarding long-term outcome in children is lacking. We report a favourable outcome 11 years after tricuspid valvectomy in early infancy without subsequent surgery or other cardiac interventions. Specific criteria for timing of re-intervention are lacking. Application of adult tricuspid and pulmonary regurgitation recommendations is helpful but has limitations.

Long-term effect on outcome of clozapine in chronic therapy-resistant schizophrenic patients

1997 ◽  
Vol 12 (S5) ◽  
pp. 353s-355s ◽  
Author(s):  
LH Lindström ◽  
T Lundberg
Keyword(s):  
Duration Of Treatment ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Clozapine Treatment ◽  
Long Term Effect ◽  
Chronic Therapy ◽  
Schizophrenic Patients ◽  
The Mean

SummaryControlled clinical trials have shown that the atypical neuroleptic clozapine is highly effective in schizophrenic patients who are unresponsive to conventional neuroleptic agents. The long-term outcome of clozapine treatment was studied in 122 patients who were treated between 1974 and 1991. The mean duration of treatment was 5.2 years. At follow-up, 74 patients (61%) were still receiving clozapine. Only 11 patients discontinued treatment because of adverse events and eight because of poor compliance. Clinical improvement was seen in 87% of patients; 40% had resumed employment after 2 years' treatment. About one-third of patients who received clozapine for 5–10 years continued to improve during this time; this was probably because of a continuing process of socialisation. Thus, clozapine offers important advantages in schizophrenic patients resistant to conventional neuroleptics in terms of long-term efficacy and lack of extrapyramidal side-effects.

scholarly journals Study of the Long-Term Results of Decompressive Craniectomy after Severe Traumatic Brain Injury Based on a Series of 60 Consecutive Cases

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Gaétane Gouello ◽  
Olivier Hamel ◽  
Karim Asehnoune ◽  
Eric Bord ◽  
Roger Robert ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Intracranial Hypertension ◽  
Decompressive Craniectomy ◽  
Severe Traumatic Brain Injury ◽  
Favourable Outcome ◽  
Long Term Results ◽  
Term Outcome ◽  
Long Term Outcome

Background. Decompressive craniectomy can be proposed in the management of severe traumatic brain injury. Current studies report mixed results, preventing any clear conclusions on the place of decompressive craniectomy in traumatology.Methods. The objective of this retrospective study was to evaluate the results of all decompressive craniectomies performed between 2005 and 2011 for refractory intracranial hypertension after severe traumatic brain injury. Sixty patients were included. Clinical parameters (Glasgow scale, pupillary examination) and radiological findings (Marshall CT scale) were analysed. Complications, clinical outcome, and early and long-term Glasgow Outcome Scale (GOS) were evaluated after surgery. Finally, the predictive value of preoperative parameters to guide the clinician’s decision to perform craniectomy was studied.Results. Craniectomy was unilateral in 58 cases and the mean bone flap area was 100 cm2. Surgical complications were observed in 6.7% of cases. Mean followup was 30 months and a favourable outcome was obtained in 50% of cases. The initial Glasgow Scale was the only statistically significant predictive factor for long-term outcome.Conclusion. Despite the discordant results in the literature, this study demonstrates that decompressive craniectomy is useful for the management of refractory intracranial hypertension after severe traumatic brain injury.

Are There Predictive Factors for Long-Term Outcome after Withdrawal in Drug-Induced Chronic Daily Headache?

Cephalalgia ◽  
2001 ◽  
Vol 21 (6) ◽  
pp. 691-696 ◽  
Author(s):  
GG Tribl ◽  
P Schnider ◽  
C Wöber ◽  
S Aull ◽  
A Auterith ◽  
...  
Keyword(s):  
Chronic Daily Headache ◽  
Favourable Outcome ◽  
Drug Induced ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Clear Cut ◽  
Standardized Interview ◽  
Daily Headache ◽  
Drug Overuse

Objectives To investigate prognostic factors for long-term outcome of patients after inpatient withdrawal because of drug-induced chronic daily headache. Procedures Fifty-five patients (36 females) were re-examined by means of a standardized interview after inpatient withdrawal. The mean observation period was 9.28 ± 2.85 years (mean ± sd; median 8.58; range 5.00–13.50). Results Five years after withdrawal, one-third of the patients (34.6%) had an overall favourable outcome, one-third (32.7%) had no recurrent drug overuse and reported a clear-cut improvement of headache, and one-third (32.7%) developed recurrent drug overuse. Most relapses occurred within 2 years, and a small percentage within 5 years. No predictors for long-term outcome after inpatient withdrawal were found. Conclusions All patients with drug-induced chronic daily headache should be considered as good candidates for inpatient withdrawal, and no patient should be excluded from that therapy.

Nutrition and Schizophrenia: An Epidemiological and Clinical Perspective

2003 ◽  
Vol 17 (3) ◽  
pp. 211-219 ◽  
Author(s):  
Malcolm Peet
Keyword(s):  
Industrial Revolution ◽  
Saturated Fat ◽  
Developed Countries ◽  
Indigenous Populations ◽  
New Paradigm ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Increased Risk ◽  
Schizophrenic Patients

There is well accepted evidence that the long-term outcome of schizophrenia is better in developing than in developed countries. Socio-cultural factors, which are as yet unidentified, have been postulated to explain this. There is also disputed evidence that schizophrenia was rare in indigenous populations and increased when they came into contact with Western or industrialised cultures, and that there was an increase in the rate of schizophrenia during the Industrial Revolution. These epidemiological and historical findings point to diet as a possible mediating factor in schizophrenia. Ecological studies have indicated that a worse outcome of schizophrenia is associated with higher consumption of saturated fat and sugar. It is also known that schizophrenic patients have increased insulin resistance and are at increased risk of developing diabetes and coronary heart disease. These findings suggest a new paradigm for our understanding of the causation and treatment of schizophrenia.

A 15-year follow-up study of patients with panic disorder

2003 ◽  
Vol 18 (8) ◽  
pp. 401-408 ◽  
Author(s):  
Sven Andersch ◽  
Jerker Hetta
Keyword(s):  
Panic Disorder ◽  
Favourable Outcome ◽  
Drug Trial ◽  
Panic Attacks ◽  
Daily Functioning ◽  
Short Term Treatment ◽  
Term Outcome ◽  
Long Term Outcome

AbstractBackgroundPanic disorder (PD) is generally regarded as a chronic condition with considerable variation in severity of symptoms.AimsTo describe the long-term outcome of naturalistically treated PD.MethodsFifty-five outpatients with PD, who participated in a placebo-controlled drug trial of the efficacy of alprazolam and imipramine 15 years ago were reassessed with the same instruments used in the original study.ResultsComplete recovery (no panic attacks and no longer on medication during the last 10 years) was seen in 18% of patients, and an additional 13% recovered but were still on medication. Fifty-one percent experienced recurrent anxiety attacks whereas 18% still met diagnostic criteria for PD. The incidence of agoraphobia decreased from 69% to 20%. Patients with agoraphobia at admission tended to have a poorer long-term outcome according to daily functioning compared with patients without agoraphobia at admission, although both groups reported improved daily functioning at follow-up. Maintenance medication was common. No benzodiazepine abuse was reported.ConclusionPD has a favourable outcome in a substantial proportion of patients. However, the illness is chronic and needs treatment. The short-term treatment given in the drug trial had no influence on the long-term outcome.

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