Familial Aspects of Obsessive-Compulsive Neurosis

1987 ◽  
Vol 151 (4) ◽  
pp. 528-534 ◽  
Author(s):  
Patrick McKeon ◽  
Robin Murray

The first-degree relatives of 50 obsessive-compulsive patients and those of matched controls completed the General Health Questionnaire (GHQ) and the Leyton Obsessional Inventory (LOI). Relatives who were identified as possible ‘cases' by their high GHQ scores, or by their own or informant relatives' reports, were interviewed using the Schedule for Affective Disorders and Schizophrenia. Index relatives had a significantly higher lifetime prevalence of mental illness (36%) than had those of controls (17%), due mainly to an excess of depressive and neurotic disorders. However, only one relative from each group was diagnosed as having definite obsessive-compulsive neurosis. In addition, the LOI scores were similar for the index and control relatives.

2001 ◽  
Vol 35 (2) ◽  
pp. 231-235 ◽  
Author(s):  
Susan Donath

Objective: To investigate the specificity and sensitivity of three different scoring methods of the 12-item General Health Questionnaire (GHQ-12) and hence to determine the best GHQ-12 threshold score for the detection of mental illness in community settings in Australia. Method: Secondary data analysis of the 1997 Australian National Survey of Health and Wellbeing (n = 10 641), using the Composite International Diagnostic Interview as the gold standard for diagnosis of mental illness. Results: The area under the Receiver Operating Characteristic (ROC) curve for the C-GHQ scoring method was 0.84 (95% CI = 0.83–0.86) compared with the area for the standard scoring method of 0.78 (95% CI = 0.76–0.80). The best threshold with C-GHQ was 3/4, with sensitivity 82.9% (95% CI = 80.2–85.5%) and specificity 69.0% (95% CI = 68.6–69.4%). The best threshold score with the standard scoring method was 0/1, with sensitivity 75.4% (95% CI = 72.5–78.4%) and specificity 69.9% (95% CI = 69.5–70.3%). These were also the best thresholds for a subsample of the population who had consulted a health practitioner in the previous 4 weeks. Conclusion: In the Australian setting, the C-GHQ scoring method is preferable to the standard method of scoring the GHQ-12. In Australia the GHQ-12 appears to be a less useful instrument for detecting mental illness than in many other countries.


1994 ◽  
Vol 24 (2) ◽  
pp. 149-156 ◽  
Author(s):  
Toshinori Kitamura ◽  
Mari A. Toda ◽  
Satoru Shima ◽  
Masumi Sugawara

Objective: The authors examined the variability of the validity of the General Health Questionnaire (GHQ) on two different occasions. Method: The subjects were 120 pregnant women attending an antenatal clinic of a general hospital in Japan. The GHQ was distributed twice—in the first and third trimesters. They were then interviewed by a psychiatrist blind to the GHQ scores using the standard and the “change” version of the Schedule for Affective Disorders and Schizophrenia (SADS). Results: Of the 120 women, 108 and ninety-eight completed the GHQ and were successfully interviewed in the first and third trimesters, respectively. Seventeen percent (18/108) and 13 percent (13/98) women were given RDC diagnoses in the first and third trimesters, respectively: They were designated as cases. Despite a satisfactory discriminatory power of the GHQ on the first occasion [1], the validity measures of the GHQ on the second occasion were generally poor. Thus, the sensitivity was 39 percent and specificity 82 percent for the cut-off point of 7/8. Conclusions: The GHQ should be validated separately when distributed repeatedly to the same subjects.


2018 ◽  
Vol 6 ◽  
pp. 205031211878809 ◽  
Author(s):  
Salman Alahmed ◽  
Irfan Anjum ◽  
Emad Masuadi

Objectives: Cultural beliefs often affect people’s attitude toward mental illness and their help-seeking behavior. Belief in superstitious causes of mental illness can lead to seeking help from non-medical practitioners, which might hinder treatment. This study aimed to explore the perception of mental illness and help-seeking behavior among healthcare students. Methods: A cross-sectional study carried out on a sample of 400 randomly selected undergraduate health professional students in Riyadh. Data collection involved two self-administered questionnaires: the causes and treatment routes for a female vignette with psychosis and the General Health Questionnaire-28. Results: The mean age of participants was 20.9 years, and 68.2% were male. Although participants reported a lack of personal history of mental illness (81.9%), female participants were more likely to disclose psychological distress as measured by General Health Questionnaire-28 (67.6%). Mental illness (47.2%) was chosen as the main reason for the problem depicted by the female vignette. General Health Questionnaire-28 scores for “caseness” did not affect perception about psychosis versus non-caseness. Factor analysis produced four dimensions for causes of psychosis: “social,” “psychobiological,” “superstitious,” and “socially undesirable”; and two treatment routes: “clinical” versus “social interventions.” Male participants leaned toward social factors for the cause of psychosis and were more likely to endorse social interventions for treatment. Conclusion: Healthcare students in Riyadh remained supportive of a biomedical approach toward the causation and treatment of mental illness. The use of religious practices as an adjunct was apparent. Students, especially females, were prone to experience more psychological distress.


2011 ◽  
Vol 38 (S 01) ◽  
Author(s):  
F Friedrich ◽  
R Alexandrowicz ◽  
N Benda ◽  
G Cerny ◽  
J Wancata

2011 ◽  
Vol 21 (9) ◽  
pp. 954-961 ◽  
Author(s):  
Wei Gao ◽  
Daniel Stark ◽  
Michael I. Bennett ◽  
Richard J. Siegert ◽  
Scott Murray ◽  
...  

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