A Long-term Retrospective Follow-up Study of Patients Treated with Prophylactic Lithium Carbonate

1987 ◽  
Vol 150 (2) ◽  
pp. 175-179 ◽  
Author(s):  
C. Page ◽  
S. Benaim ◽  
F. Lappin
Keyword(s):  
Side Effects ◽  
Complete Remission ◽  
Lithium Carbonate ◽  
Favourable Outcome ◽  
Lithium Level ◽  
Follow Up Study ◽  
High Incidence ◽  
Average Serum

Patients suffering from unipolar and bipolar affective illness, who began treatment with prophylactic lithium carbonate during a 5-year period, were followed up and 59 out of 101 interviewed. Most had been taking lithium for at least 13 years: 49% had a complete remission, 41% a partial but significant response, and 10% no response. No specific individual or illness factor was found to correlate with favourable outcome, and no correlation between average serum lithium level and outcome. No side-effects could be associated specifically with the long-term use of lithium, but there was a surprisingly high incidence of clinical hypothyroidism.

Does Mechanical Thrombectomy in Acute Embolic Stroke Have Long-term Side Effects on Intracranial Vessels? An Angiographic Follow-up Study

2012 ◽  
Vol 36 (3) ◽  
pp. 629-636 ◽  
Author(s):  
Wiebke Kurre ◽  
Marta Aguilar Pérez ◽  
Diana Horvath ◽  
Elisabeth Schmid ◽  
Hansjörg Bäzner ◽  
...  
Keyword(s):  
Side Effects ◽  
Mechanical Thrombectomy ◽  
Embolic Stroke ◽  
Follow Up Study

scholarly journals 0592 DENTAL SIDE EFFECTS OF LONG TERM OBSTRUCTIVE SLEEP APNEA THERAPY. A 10 YEAR FOLLOW UP STUDY

SLEEP ◽  
2017 ◽  
Vol 40 (suppl_1) ◽  
pp. A219-A220
Author(s):  
JA Uniken Venema ◽  
A Hoekema ◽  
M Doff
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Side Effects ◽  
Follow Up Study ◽  
Obstructive Sleep

scholarly journals Ten-year survival and late sequelae in testicular cancer patients treated with cisplatin, vinblastine, and bleomycin.

1989 ◽  
Vol 7 (8) ◽  
pp. 1099-1104 ◽  
Author(s):  
G Stoter ◽  
A Koopman ◽  
C P Vendrik ◽  
A Struyvenberg ◽  
D T Sleyfer ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Renal Function ◽  
Side Effects ◽  
Sexual Dysfunction ◽  
Maintenance Chemotherapy ◽  
Cure Rate ◽  
Late Sequelae ◽  
Follow Up Study

This 10-year follow-up study of 91 patients with disseminated testicular nonseminomatous cancer, treated with cisplatin, vinblastine, and bleomycin (PVB) induction chemotherapy and vinblastine plus bleomycin maintenance chemotherapy for a planned period of 2 years, shows a 63% cure rate. The predominant long-term sequelae are neurological and sexual dysfunction in 68% and 40% of patients, respectively. Two patients died of myocardial infarction. Sixteen percent of patients developed hypertension, 23% Raynaud's phenomenon, and 25% ototoxicity. Despite the long-term side effects, 90% of the patients who responded to a questionnaire are fully employed. This study shows that the maintenance chemotherapy has contributed to the incidence and/or degree of neurotoxicity, hypertension, and renal function disturbance.

A Short Weekly Chemotherapy Regimen (ACOP-B) Followed by Involved Field Radiotherapy in Limited Stage Aggressive Non-Hodgkin Lymphoma. Multicentric Analyses of Toxicity, Efficacy and Long Term Follow up.

Blood ◽  
2006 ◽  
Vol 108 (11) ◽  
pp. 2435-2435
Author(s):  
Maria Giuseppina Cabras ◽  
Roberto Freilone ◽  
Angela Mamusa ◽  
Paolo Dessalvi ◽  
Anna Tonso ◽  
...  
Keyword(s):  
Overall Survival ◽  
Side Effects ◽  
Complete Remission ◽  
Elderly Patients ◽  
Aggressive Lymphoma ◽  
Short And Long Term ◽  
Involved Field ◽  
Involved Field Radiotherapy

Abstract Patients with Ann Arbor stages I and II diffuse large cell lymphoma (DLCL) represent a significant proportion of patients with aggressive lymphoma. Recent clinical research are developing low intensity chemotherapy approach in order to minimize short and long term side effects while maintaining high success rate. Moreover very limited studies are available on elderly patients. Since 1993 we used a brief weekly (six weeks) chemotherapy scheme (Doxorubicin, Cyclophosphamide, Bleomycin, Vincristine and Prednisone = ACOP-B) followed by involved field radiotherapy in patients with localized stage aggressive lymphoma and examined long term results and side effects in a general haematology population without age limit. Two hundred and six consecutive patients (89 females) affected by localized aggressive lymphoma aged from 18 to 85 years old (median 57) treated between January 1st, 1993 and December 31st, 2004 were enrolled in this analysis. Minimum follow up was 18 months. Inclusion criteria was well documented nodal or extranodal stage IA (including bulky) or IIA disease. Bulky disease was defined as a 10 cm or more mass in maximal diameter. Treatment was completed as designed in 183 over 206 patients (88%). Three patients did not complete the six scheduled cycles of chemotherapy: one died during chemotherapy and two because of disease progression. Twenty additional patients did not receive radiotherapy: 12 patients had an initial site of disease totally resected (9 with gastric lymphoma and 3 with small or large bowel lymphoma). One hundred and ninety-seven patients (96%) achieved a complete remission, two patients obtained a partial response; three patients had no response (four patients were not valuable). At a median follow-up 66 months one hundred and seventy patients are alive (82 %) 168 of them free of disease. Twenty-nine patients (15%) experienced relapse after achieving a complete remission. The median time to relapse was 46 months with a very wide range (1–143 months). Among these twenty-nine patients eighteen (62%) are alive and free of lymphoma after second line therapy. Twenty-six (13%) patients have died, 13 (5%) by lymphoma progression, one for toxicity and 12 (6%) from other causes while in complete remission. After 13 years the Kaplan-Meier (K-M) probability of overall survival and disease free survival were 80% (95%CI 72–88%) and 55% (95% CI 33–76%), respectively. We specifically analyzed patients over 60 years: they were 93 (median age 70 years). In this group of elderly patients the treatment was completed as designed in 90% and the 12 years K-M probability of overall survival was 60%. Seven patients presented secondary malignancies which were diagnosed at a median of three years (range 2–8) after chemo-radio therapy. Four patients died by solid neoplasm. Overall incidence of secondary malignancy was 0.68/100/anno. The ACOP-B regimen plus involved field radiotherapy is a short and long term well tolerated and effective chemotherapy scheme for very well defined limited stage aggressive non-Hodgkin lymphomas in all age categories.

THE EMOTIONAL CORRELATES OF SYDENHAM'S CHOREA

PEDIATRICS ◽  
1965 ◽  
Vol 35 (1) ◽  
pp. 42-49
Author(s):  
John M. Freeman ◽  
Alan M. Aron ◽  
Jean E. Collard ◽  
Mary C. MacKay
Keyword(s):  
Psychological Factors ◽  
Psychiatric Disturbance ◽  
Psychological Disturbance ◽  
Follow Up Study ◽  
Sydenham’S Chorea ◽  
High Incidence ◽  
Long Term Follow Up ◽  
Sydenham's Chorea

1. During a long-term follow-up study of patients previously hospitalized with Sydenham's chorea, a high incidence of psychological disturbance was encountered prior to the onset of chorea, and at the time of current evaluation, an average of 29 years later. 2. Seventy-five per cent of patients with Sydenham's chorea were currently found to manifest evidence of psychiatric disturbance. 3. A control population similarly evaluated showed a 25% incidence of psychiatric disability—about the expected incidence for the general population. 4. This study emphasizes the need to consider psychological factors as part of the total evaluation of patients with Sydenham's chorea.

Dental side effects of long-term obstructive sleep apnea therapy: a 10-year follow-up study

2019 ◽  
Vol 24 (9) ◽  
pp. 3069-3076 ◽  
Author(s):  
Julia Anne Margarethe Uniken Venema ◽  
Michiel H. J. Doff ◽  
Dilyana S. Joffe-Sokolova ◽  
Peter J. Wijkstra ◽  
Johannes H. van der Hoeven ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Side Effects ◽  
Follow Up Study ◽  
Obstructive Sleep

Recurrent Brief Episodes with Psychotic Features in Adolescence: Periodic Psychosis of Puberty Revisited

1995 ◽  
Vol 167 (4) ◽  
pp. 507-513 ◽  
Author(s):  
Kazuhiko Abe ◽  
Mikio Ohta
Keyword(s):  
Complete Remission ◽  
Follow Up Study ◽  
Regular Menses ◽  
Icd 10 ◽  
First Onset ◽  
Long Term Prognosis ◽  
Psychotic Features ◽  
Depressive Episodes

BackgroundThere are many reports of adolescents with periodic episodes each followed by complete remission within 2 weeks, but the nosology and long-term prognosis of such cases have not been elucidated.MethodA prospective follow-up study on 11 cases (nine girls and two boys) meeting predetermined criteria is reported.ResultsThe first several episodes were found to meet ICD–10 symptomatic criteria for recurrent depressive disorder in all cases, and, except for two cases, showed psychotic features. The episodes were linked to one phase of the menstrual cycle in only two of six girls with regular menses. There were no recurrences while on lithium in eight of nine cases. Of eight patients followed up 5–14 years after the first onset, three had been well, three had become bipolar and two were still suffering from brief depressive episodes.ConclusionsRecurrent brief episodes in adolescence tend to show a near-monthly rhythm and psychotic features. Most of them appear to be manifestations of affective illness and may be treated and prevented as such.

733: The Prognostic Value of E-Cadherin, Alpha-, and Beta-Catenin in Invasive Bladder Cancer Patients: Long Term Follow-Up Study

2004 ◽  
Vol 171 (4S) ◽  
pp. 194-195
Author(s):  
Kyoichi Tomita ◽  
Haruki Kume ◽  
Keishi Kashibuchi ◽  
Satoru Muto ◽  
Shigeo Horie ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Patients ◽  
Prognostic Value ◽  
Invasive Bladder Cancer ◽  
Beta Catenin ◽  
Follow Up Study ◽  
Long Term Follow Up ◽  
E Cadherin
Sign in / Sign up

Export Citation Format

Share Document