Multiple Pathology in a Mentally Handicapped Individual

1986 ◽  
Vol 149 (3) ◽  
pp. 377-378 ◽  
Author(s):  
E. Akuffo ◽  
D. A. MacSweeney ◽  
A. K. Gajwani
Keyword(s):  
Disease Process ◽  
Single Individual ◽  
Mentally Handicapped ◽  
Multiple Pathology ◽  
Handicapped Individual

A doctor is trained, perhaps over-trained, to try to limit his diagnosis to a single disease process or entity. This may lead on occasion to a somewhat blinkered approach to the management of patients. The following case illustrates multiple and concomitant pathology in a single individual.

scholarly journals The development of a nursing assessment instrument for the mentally handicapped individual

1999 ◽  
Vol 4 (3) ◽  
pp. 59-72 ◽  
Author(s):  
Willem J Fourie ◽  
Lily Van Rhyn ◽  
Marlene J Viljoen
Keyword(s):  
Full Text ◽  
Assessment Instrument ◽  
Mentally Handicapped ◽  
Nursing Assessment ◽  
Mental Handicap ◽  
Handicapped Individual

Because mental handicap is a lifelong condition, mentally handicapped individuals and their families experience unique needs and problems, which require sound assessment by the nurse to enable her to intervene effectively.OpsommingVanwee die feit dat geestesgestremdheid 'n lewenslange toestand is, ervaar geestesgestremde persone en hul families unieke behoeftes en probleme wat deeglike beraming deur verpleegkundiges vereis, ten einde effektiewe ingn'ping te verseker. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

Ulcerogenic Tumors of the Pancreas

1968 ◽  
Vol 26 ◽  
pp. 186-187
Author(s):  
J. C. Garancis ◽  
J. F. Kuzma ◽  
S. D. Wilson ◽  
E. H. Ellison
Keyword(s):  
Endoplasmic Reticulum ◽  
Tumor Cells ◽  
Islet Cell ◽  
Disease Process ◽  
Central Core ◽  
Islet Cell Tumors ◽  
Opaque Zone ◽  
Granular Form ◽  
Zollinger Ellison Syndrome

It has been proposed that a gastrin-like hormone elaborated by non-beta islet tumors of the pancreas may be responsible for a fulminating ulcer diathesis. Subsequently, a potent gastric secretagogue was isolated from ulcerogenic tumors of the pancreas. This disease process is known now as “Zollinger-Ellison syndrome”.In our studies of two cases of Zollinger-Ellison syndrome, pancreatic lesions were identified as alpha islet cell tumors (Fig. 1). Tumor cells were fairly uniform. The sizes of the alpha granules were not significantly different, but their number and distribution varied greatly from one cell to another. Each granule consisted of a round, highly dense central core, separated from the limiting membrane by an opaque zone. The granular form of the endoplasmic reticulum was particularly prominent. Numerous mitochondria, round or elongated, were dispersed throughout the cytoplasm. Individual or clusters of lysosomes were observed in the majority of cells.

Electron microscopy analysis of degenerating pancreatic ß cells in transgenic mice expressing the MHC Class I antigen Dd

1990 ◽  
Vol 48 (3) ◽  
pp. 548-549
Author(s):  
T. A. Stewart ◽  
D. Liggitt ◽  
S. Pitts ◽  
L. Martin ◽  
M. Siegel ◽  
...  
Keyword(s):  
Type I Diabetes ◽  
Disease Process ◽  
Class Ii ◽  
Class I ◽  
Type I ◽  
Aberrant Expression ◽  
Mhc Molecules ◽  
Endogenous Insulin ◽  
Class Ii Mhc ◽  
Ifn Γ

Insulin-dependant (Type I) diabetes mellitus (IDDM) is a metabolic disorder resulting from the lack of endogenous insulin secretion. The disease is thought to result from the autoimmune mediated destruction of the insulin producing ß cells within the islets of Langerhans. The disease process is probably triggered by environmental agents, e.g. virus or chemical toxins on a background of genetic susceptibility associated with particular alleles within the major histocompatiblity complex (MHC). The relation between IDDM and the MHC locus has been reinforced by the demonstration of both class I and class II MHC proteins on the surface of ß cells from newly diagnosed patients as well as mounting evidence that IDDM has an autoimmune pathogenesis. In 1984, a series of observations were used to advance a hypothesis, in which it was suggested that aberrant expression of class II MHC molecules, perhaps induced by gamma-interferon (IFN γ) could present self antigens and initiate an autoimmune disease. We have tested some aspects of this model and demonstrated that expression of IFN γ by pancreatic ß cells can initiate an inflammatory destruction of both the islets and pancreas and does lead to IDDM.

Auditory Dysfunction in Alzheimer's Disease

2010 ◽  
Vol 15 (1) ◽  
pp. 4-11 ◽  
Author(s):  
Sridhar Krishnamurti
Keyword(s):  
Alzheimer’S Disease ◽  
Older Adults ◽  
Alzheimer's Disease ◽  
Health Care ◽  
Care Setting ◽  
Neurodegenerative Disorder ◽  
Disease Process ◽  
Clinical Protocols ◽  
Speech Language Pathologist ◽  
Auditory Dysfunction

Alzheimer's disease is neurodegenerative disorder which affects a growing number of older adults every year. With an understanding of auditory dysfunction in Alzheimer's disease, the speech-language pathologist working in the health care setting can provide better service to these individuals. The pathophysiology of the disease process in Alzheimer's disease increases the likelihood of specific types of auditory deficits as opposed to others. This article will discuss the auditory deficits in Alzheimer's disease, their implications, and the value of clinical protocols for individuals with this disease.

Drug-Induced Movement Disorders

2015 ◽  
Vol 25 (2) ◽  
pp. 70-77
Author(s):  
Amy Lustig ◽  
Cesar Ruiz
Keyword(s):  
Movement Disorders ◽  
Medical Management ◽  
Disease Process ◽  
Underlying Disease ◽  
Extrapyramidal Symptoms ◽  
Drug Induced ◽  
General Overview ◽  
Management Approaches ◽  
Broad Understanding ◽  
Underlying Disease Process

The purpose of this article is to present a general overview of the features of drug-induced movement disorders (DIMDs) comprised by Parkinsonism and extrapyramidal symptoms. Speech-language pathologists (SLPs) who work with patients presenting with these issues must have a broad understanding of the underlying disease process. This article will provide a brief introduction to the neuropathophysiology of DIMDs, a discussion of the associated symptomatology, the pharmacology implicated in causing DIMDs, and the medical management approaches currently in use.

The Concepts of Prevalence and Incidence as Applied to the Study of Development and Duration of Disease

1968 ◽  
Vol 7 (02) ◽  
pp. 111-117 ◽  
Author(s):  
M. Kashgahian
Keyword(s):  
Mass Screening ◽  
Disease Process ◽  
Incidence Data ◽  
Disease States ◽  
History Of ◽  
Duration Of Disease ◽  
Process Methodology

The proper use of prevalence and incidence data can result in an effective way to study the history of the disease process. Methodology is given whereby the progression, duration and transition of diseases can be elucidated. Prevalence and incidence have been redefined and used in an unconventional way in view of new types of data which are being generated by mass screening projects for disease which are able to discover presymptomatic and preclinical disease states.

LIVING WITH HEPATITIS: THE EFFECT OF INFECTED SUBJECTS ON EVERYDAY LIFE

2020 ◽  
Vol 4 (12) ◽  
Author(s):  
Khaled Hassan
Keyword(s):  
Hepatitis B ◽  
Everyday Life ◽  
Disease Process ◽  
Analysis Data ◽  
Structured Interview ◽  
Lifestyle Changes ◽  
Life Change Events ◽  
Life Change ◽  
The Everyday ◽  
Content Review

To identify changes in the everyday life of hepatitis subjects, we conducted a descriptive, exploratory, and qualitative analysis. Data from 12 hepatitis B and/or C patients were collected in October 2011 through a semi-structured interview and subjected to thematic content review. Most subjects have been diagnosed with hepatitis B. The diagnosis period ranged from less than 6 months to 12 years, and the diagnosis was made predominantly through the donation of blood. Interferon was used in only two patients. The findings were divided into two groups that define the interviewees' feelings and responses, as well as some lifestyle changes. It was concluded that the magnitude of phenomena about the disease process and life with hepatitis must be understood to health professionals. Keywords: Hepatitis; Nursing; Communicable diseases; Diagnosis; Life change events; Nursing care.

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