The Relationship between Parkinson's Disease and Dementia: A study using Proton NMR Imaging Parameters

1985 ◽  
Vol 147 (4) ◽  
pp. 380-382 ◽  
Author(s):  
J. A. O. Besson ◽  
W. J. Mutch ◽  
F. W. Smith ◽  
F. M. Corrigan

The value of the spin lattice relaxation time (T1) obtained during nuclear magnetic resonance imaging of the brain was studied in patients with idiopathic Parkinson's disease, with and without dementia. T1 increases significantly in the basal ganglia and cerebral white matter of the demented and non-demented groups. T1 of the cerebral white matter correlates with the severity of dementia.

1985 ◽  
Vol 146 (1) ◽  
pp. 31-35 ◽  
Author(s):  
J. A. O. Besson ◽  
F. M. Corrigan ◽  
E. Iljon Foreman ◽  
L. M. Eastwood ◽  
F. W. Smith ◽  
...  

SummaryProton NMR imaging of the brain is rapidly becoming established as a useful investigative tool in medicine. This paper examines the usefulness of the NMR parameters—spin-lattice relaxation time (T1) and proton density (PD)—in differentiating groups of patients with senile dementia of Alzheimer type (SDAT) and multi-infarct dementia (MID) from each other, and from elderly controls. T1 values increase with severity of dementia. NMR parameters may also be of use in localising regions of brain damage.


1978 ◽  
Vol 39 (C6) ◽  
pp. C6-1215-C6-1216
Author(s):  
H. Ahola ◽  
G.J. Ehnholm ◽  
S.T. Islander ◽  
B. Rantala

1988 ◽  
Vol 11 (2) ◽  
pp. 97-102 ◽  
Author(s):  
Kiichiro Matsumura ◽  
Imaharu Nakano ◽  
Nobuo Fukuda ◽  
Hiroo Ikehira ◽  
Yukio Tateno ◽  
...  

2020 ◽  
Vol 44 (44) ◽  
pp. 19393-19403
Author(s):  
Krishna Kishor Dey ◽  
Manasi Ghosh

The correlation between the structure and dynamics of omeprazole is portrayed by extracting CSA parameters through the 13C 2DPASS CP-MAS SSNMR experiment, site specific spin–lattice relaxation time by Torchia CP experiment, and calculation of the molecular correlation time.


1985 ◽  
Vol 40 (11) ◽  
pp. 1075-1084
Author(s):  
W. T. Sobol ◽  
K.R. Sridharan ◽  
I. G. Cameron ◽  
M. M. Pintar

The frequency dependence of the spin-lattice relaxation time T1 was measured at three temperatures near one of the Zeeman-tunneling level matching resonances for pentamethylbenzene. These measurements are correlated with 71 temperature dependence data from the literature. It is shown that the frequency dependence of the Zeeman-torsion coupling time cannot be explained in terms of the semiclassical perturbation theory using time correlation functions. A three bath polarization transfer model is also employed and the applicability of both models discussed. Zeeman-torsion coupling is further investigated using a saturation sequence and the results are compared with the predictions of the three bath polarization transfer model.


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