Social Support and Long-Term Lithium Outcome

1985 ◽  
Vol 147 (3) ◽  
pp. 272-275 ◽  
Author(s):  
Ralph A. O'Connell ◽  
Julia A. Mayo ◽  
Leonard K. Eng ◽  
J. Sidney Jones ◽  
Richard H. Gabel
Keyword(s):  
Social Support ◽  
Psychosocial Factors ◽  
Social Adjustment ◽  
Lithium Treatment ◽  
Bipolar Affective Disorder ◽  
Global Assessment Scale ◽  
Factors Affecting ◽  
One Year ◽  
Bipolar Patients

SummaryThe failure rate in long-term lithium treatment of bipolar affective disorder is in the range of 20 to 30%, even with rigorous diagnostic criteria and adequate serum lithium levels. This may be due to a variety of biologic and psychosocial factors. Psychosocial factors affecting treatment outcome were studied in 60 RDC diagnosed bipolar patients treated with lithium for one year. Outcome was measured using an affective episode score, a social adjustment scale and a global assessment scale. Social support was the factor most strongly correlated with a good outcome on all three measures.

Self-esteem in Recovered Bipolar and Unipolar Out-patients

1993 ◽  
Vol 163 (6) ◽  
pp. 755-762 ◽  
Author(s):  
D. Pardoen ◽  
F. Bauwens ◽  
A. Tracy ◽  
F. Martin ◽  
J. Mendlewicz
Keyword(s):  
Social Adjustment ◽  
Clinical Characteristics ◽  
Self Esteem ◽  
Normal Control Group ◽  
Basic Component ◽  
Control Group ◽  
Bipolar Patients ◽  
The Relationship ◽  
Depressive Patients

The hypothesis of a low self-esteem in depressive patients was tested using the Rosenberg Self-Esteem Scale in 24 recovered unipolar and 27 recovered bipolar patients, compared with a normal control group of 26 subjects matched for age and sex. The hypothesis was confirmed only for unipolars; bipolar patients presented a self-esteem score not significantly different from normal scores. Self-esteem was not related to clinical characteristics of the affective disorder, suggesting that low self-esteem may be a basic component of a depression-prone personality. The investigation of the relationship between self-esteem and social adjustment confirmed the presence of social conformism in bipolar patients and rigidly set low self-esteem in unipolar patients. These results should stimulate the evaluation of different psychotherapeutic treatments in the long-term psychosocial management of affectively ill patients.

scholarly journals Quality of life and Social Support Among Diagnose Bipolar Patients

2021 ◽  
Vol 15 (5) ◽  
pp. 932-935
Author(s):  
M Adnan ◽  
T Khan ◽  
B Razzaq ◽  
R Ghaffar ◽  
S Batool ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Social Support ◽  
Psychiatric Treatment ◽  
Bipolar Affective Disorder ◽  
Well Being ◽  
Recovery Phase ◽  
Cross Sectional ◽  
Quality Of Life Scale ◽  
Bipolar Patients

Aim: To ascertain the relationship between quality of life and social support in bipolar patients who have been diagnosed. STUDY DESIGN: cross-sectional research design Place and duration of the study: The research was performed impatiently on the Sheikh Zayed Medical College, Rahim Yar Khan at the Department of Psychiatry and Behavioral Sciences, which ran from January 2018 to July of 2019. Method: Data was retrieved from 100 patients, with diagnosed patients of bipolar affective disorder. Quality of life and social support were assessed by quality of life scale (QOLS) developed by Burckhardt and Berline social support scale (BSSS) developed by Berline. Results: Research claims a close relationship between the presence of such things as quality of life and social help for people with Bipolar Disorder. Conclusion: Bipolar is linked to inadequate health and quality of life and social isolation, mostly due to ineffective social skills. Social support is critical to emotional stability and quality of life. It may help patients deal with difficulties and reduce depression and help in both the recovery phase and positive results of psychiatric treatment. What is currently being sought to be learned is how social care has an impact on the level of well-being for bipolar patients. Keywords: Quality of life, bipolar, validation, generalization

Depression in Inpatients: Bipolar vs Unipolar

2003 ◽  
Vol 92 (3) ◽  
pp. 1031-1039 ◽  
Author(s):  
Stella Dorz ◽  
Giuseppe Borgherini ◽  
Donatella Conforti ◽  
Caterina Scarso ◽  
Guido Magni
Keyword(s):  
Social Support ◽  
Major Depression ◽  
Social Adjustment ◽  
Rating Scales ◽  
Rating Scale ◽  
Social Impairment ◽  
Symptom Checklist ◽  
Bipolar Patients ◽  
Hamilton Rating Scale ◽  
Social Adjustment Scale

162 depressed inpatients were divided into three diagnostic groups to compare patterns of sociodemographic characteristics, psychopathology, and psychosocial: 35 had a single episode of major depression, 96 had recurrent major depression, and 31 had a bipolar disorder. Psychopathology and psychosocial functioning were measured by clinician-rated scales, Montgomery-Asberg Depression Rating Scale, Hamilton Rating Scale for Depression, Clinical Global Impression, and self-rating scales, Symptom Checklist-90, Social Support Questionnaire, Social Adjustment Scale. The three groups were comparable on sociodemographic variables, with the exception of education. Univariate analyses showed a similar social impairment as measured by Social Support Questionnaire, Social Adjustment Scale, and no significant differences were recorded for the psychopathology when the total test scores (Montgomery-Asberg Depression Rating Scale, Hamilton Rating Scale for Depression, Clinical Global Index, Symptom Checklist-90) were evaluated. Some differences emerged for single items in the Montgomery-Asberg Depression Rating Scale and Symptom Checklist-90. These findings suggest a substantial similarity among the three groups. Results are discussed in terms of the clinical similarities between unipolar and bipolar patients during a depressive episode as well as the limitations of cross-sectional study implies.

scholarly journals A retrospective study of various factors affecting infertility in Rajasthan, India

2020 ◽  
Vol 9 (7) ◽  
pp. 2910
Author(s):  
Preksha T. Singh ◽  
Saroj Choudhary ◽  
Shreyans D. Singhvi
Keyword(s):  
Retrospective Study ◽  
Reproductive Organs ◽  
Factors Affecting ◽  
Sperm Abnormality ◽  
Ultrasound Sonography ◽  
Early Case ◽  
Psychological Impairment ◽  
One Year ◽  
Biochemical Examination

Background: Infertility is seen fairly common in these days and it cause not only reproductive but also psychological impairment of the parents. Infertility leads to multitude of personal as well as societal repercussions. There are various advances in technology which help the parents suffering from infertility. Infertility is defined as the failure to conceive after one year of regular intercourse in women <35 years not using contraception and after six months in women >35 years.Methods: A retrospective study of 400 females and their husbands’ coming to the department of gynecology, Umaid Hospital, Jodhpur, Rajasthan was undertaken from February 2020 to March 2020. A structural self-constructed questionnaire was used in the study. A well-informed verbal consent was taken by the participants of the study. It had open and closed ended questions. Further, an ultrasound sonography (USG) was performed to check the reproductive organs of the patient, to find the cause of infertility, as well as biochemical examination on male sperm, was performed to find out the sperm abnormality, ejection disorders and other long-term illness.Results: In our study, we found multiple factors affecting infertility issues in females. These factors were- menstrual cycle abnormally, bleeding abnormality and years of active married life. We also found Polycystic ovarian disorder as a major underlying cause of female infertility and sperm abnormality as a major cause of male infertility.Conclusions: Authors recommend frequent female routine checkups to asses early case of infertility and treat it as early as possible.

Decreased leukocyte telomere length in male patients with chronic bipolar disorder: lack of effect of long-term lithium-treatment

2021 ◽  
pp. 1-25
Author(s):  
Ewa Ferensztajn-Rochowiak ◽  
Ewa Kurczewska ◽  
Błażej Rubiś ◽  
Michalina Lulkiewicz ◽  
Hanna Hołysz ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Telomere Length ◽  
Lithium Treatment ◽  
Quantitative Polymerase Chain Reaction ◽  
Accelerated Aging ◽  
Control Group ◽  
Duration Of Treatment ◽  
Control Male ◽  
Bipolar Patients

Abstract Objectives: Bipolar disorder (BD) may be connected with accelerated aging, the marker of this can be shorter telomere length (TL). Some data suggest that lithium may exert a protective effect against telomere shortening. The study aimed to compare the telomere length between patients with bipolar disorder and control subjects. The effect of long-term lithium treatment was also assessed. Methods: The study group comprised 41 patients with BD, including 29 patients treated longitudinally with lithium (mean 16.5 years) and 20 healthy people. Telomere length was assessed by the quantitative polymerase chain reaction (qPCR). Results: In the control group, the TL was significantly longer in males than in females. Male bipolar patients had significantly shorter TL compared with the control male group. In bipolar patients, there was no correlation between TL and duration of treatment. The TL was negatively correlated with age in male bipolar patients. Conclusion: The study did not confirm the lithium effect on TL in bipolar patients. TL showed gender differences, being shorter in BD males, compared to control males, and longer in healthy males, compared to control females.

Psychosocial Factors and Impact Of Cancer In British Long-Term Haematological Cancer Survivors

Blood ◽  
2013 ◽  
Vol 122 (21) ◽  
pp. 2943-2943
Author(s):  
Ania Korszun ◽  
Shah-Jalal Sarker ◽  
Kashfia Chowdhury ◽  
Charlotte Clark ◽  
Paul Greaves ◽  
...  
Keyword(s):  
Social Support ◽  
Psychological Distress ◽  
Cancer Survivors ◽  
Psychosocial Factors ◽  
Positive Impact ◽  
Medical Comorbidity ◽  
Haematological Cancer ◽  
High Level ◽  
Haematological Cancer Survivors

Abstract Background Long-term cancer survivors can experience a variety of adverse physical late effects of cancer therapy. However, psychological, e.g. depression and anxiety, and social problems can also have profoundly adverse effects on patients’ quality of life (QOL) that may not be adequately addressed in the management of long-term survivors. This study examines the effect and interaction of several disease-related, social and psychological factors on QOL in 718 British long-term haematological cancer survivors (5-40 years), who had all been treated at a single centre over 50 years. Objectives (1) to measure the prevalence of psychological distress (depression, anxiety), functioning, and fatigue in this survivor group compared to rates in the UK population and other survivor groups, (2) to investigate the effect of cancer and cancer treatment on QOL and psychological and social functioning, (3) to identify psychosocial factors associated with poorer QOL outcome. Patients and Methods Ethical approval obtained from the National Research Ethics Service Ref: 11/NE/0095 All patients, aged ≥18 years at time of entry into study, with a confirmed diagnosis of haematological malignancy and alive ≥5 years since initial diagnosis, and who had received treatment at St. Bartholomew’s Hospital, London (n=1,279) were sent a questionnaire comprising questions on physical health and validated psychosocial, functional and QOL scales, including negative and positive impact of cancer (IOC). Responses were received from 718 (response rate = 56%) patients (280 Hodgkin’s Lymphoma (HL), 326 Non-Hodgkin’s lymphoma (NHL) [109 Diffuse Large B- Lymphoma (DLBCL), 128 Follicular Lymphoma (FL), 89 other NHL (ONHL)], and 112 Acute Leukaemia (AL)). Statistical Analysis QOL measures were compared to normal population and other cancer survivor groups. Two separate hierarchical regression analyses were conducted to examine the combined association of the disease type, socio-demographics, psychological and other factors, including cancer recurrence, on negative and positive IOC scores respectively. Results Survivors had poorer QOL than the general population and 15% had levels of psychological distress indicative of a clinical depressive disorder, 18% high levels of fatigue and 10% moderate to severe impairment in functioning; all these groups showed poorer QOL. There were no statistically significant differences in psychological distress (P=0.76), fatigue levels (P=0.23) or levels of functioning (P=0.74) across different cancer diagnostic groups. Higher Negative IOC scores were significantly associated (P<0.001) with the presence of medical comorbidity, depression, low or medium level of social support, a high level of fatigue and functional impairment. Greater age at diagnosis and number of years since diagnosis were significantly (P<0.001) associated with less negative IOC. Higher positive impact scores were associated with an AL diagnosis (P=0.01) ; lower positive IOC scores were associated with white ethnicity (P<0.001), a high level of education (P=0.003), not having a partner (P=0.01), depression(P=0.04), and a low level of social support (P=0.01). Conclusion The impact of cancer on survivors’ lives is influenced by a variety of factors. By using a simple means of screening for medical comorbidity, depression and fatigue the group that needs most support could be identified early, allowing appropriate interventions to improve QOL-related measures and promote well-being by addressing both negative and positive impact of cancer. Acknowledgments We are grateful for the support of Macmillan Cancer Support Greg Woolf Foundation Cancer Research UK Barts and The London NHS Trust Disclosures: No relevant conflicts of interest to declare.

Stem cells, pluripotency and glial cell markers in peripheral blood of bipolar patients on long-term lithium treatment

2018 ◽  
Vol 80 ◽  
pp. 28-33 ◽  
Author(s):  
Ewa Ferensztajn-Rochowiak ◽  
Jolanta Kucharska-Mazur ◽  
Maciej Tarnowski ◽  
Jerzy Samochowiec ◽  
Mariusz Z. Ratajczak ◽  
...  
Keyword(s):  
Stem Cells ◽  
Glial Cell ◽  
Peripheral Blood ◽  
Lithium Treatment ◽  
Cell Markers ◽  
Bipolar Patients ◽  
Glial Cell Markers

Kidney functioning during short and long-term lithium treatment in bipolar patients

1999 ◽  
Vol 9 ◽  
pp. 215-216 ◽  
Author(s):  
S. Sofuoǧlu ◽  
C. Utaş ◽  
S.S. Aslan ◽  
C. Yalçindaǧ ◽  
M. Baştürk ◽  
...  
Keyword(s):  
Lithium Treatment ◽  
Short And Long Term ◽  
Bipolar Patients

scholarly journals Standards of Lithium Treatment Monitoring In a Teaching Hospital in South India among Bipolar Affective Disorder

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Dr. Sureshkumar Ramasamy ◽  
Dr. Shilpa Srinivasan ◽  
Dr. Shree Aarthi Ramanathan
Keyword(s):  
Serum Creatinine ◽  
Affective Disorder ◽  
Lithium Treatment ◽  
Bipolar Affective Disorder ◽  
Tertiary Care ◽  
Thyroid Stimulating Hormone ◽  
Care Hospital ◽  
Retrospective Audit ◽  
Bipolar Patients

Background: Lithium is a commonly used drug with a narrow therapeutic index, it has significant adverse effects on kidney and thyroid, and is life threatening during intoxication. Maudsley guidelines on managing bipolar affective disorder patients (BPAD) with lithium recommends checking weight at baseline and every 3rd month, serum lithium after 7th day thereafter 3 months once, renal function test and serum thyroid stimulating hormone (TSH) at baseline and 6 months once. Aim: To evaluate whether Pre-Lithium workup and monitoring is done in Bipolar affective disorder (BPAD) patients initiated on Lithium as per Maudsley prescribing guidelines in psychiatry. Method: Retrospective audit conducted in a tertiary care hospital on lithium monitoring in BPAD patients treated with lithium atleast for six months compared against Maudsley prescribing guidelines. Results: Among medical records of 114 bipolar patients fulfilling study criteria, weight and serum lithium at baseline was checked in 100% of patients; serum creatinine and TSH at baseline along with lithium at 3rd month was done in 83.3%, 78.9% and 68.4% of patients respectively. Maudsley guidelines for serum creatinine, TSH and lithium level at 6th month were met only in 43.8%, 43.8% and 72.8% of patients respectively. Conclusion: The quality of lithium monitoring in bipolar patients falls well short of accepted standards; Hence addressing the issues in monitoring and following a standard protocol can improve the effectiveness of treatment and quality of life of patients.

Sign in / Sign up

Export Citation Format

Share Document